Gene Information

Name : safC (S0214)
Accession : NP_835942.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : outer membrane usher protein
Function : -
COG functional category : S : Function unknown
COG ID : COG3519
EC number : -
Position : 230785 - 232668 bp
Length : 1884 bp
Strand : -
Note : residues 1 to 627 of 627 are 91.54 pct identical to residues 1 to 627 of 627 from GenPept : >gb|AAL19224.1| (AE008707) cytoplasmic protein [Salmonella typhimurium LT2]

DNA sequence :
ATGGATCCACGGCTACTGGAATACTACAACCGCGAACTGAGCTATCTGCGGGAAACGGGAGCCGAATTTGCCGCCCGTCA
TCCCAAAGTCGCCGCCCGGCTGGGCATGCAGGGAACGGATATTGCCGATCCGTATGTAGAGCGAATGGTCGAGGCCTTCA
GCTTCCTGACCGCCCGCACGCAGCTAAAAATTGACGCTGAATTCCCCCGTTTCACCCAGCGCCTGCTGGAAGTGGTCAGC
CCCAATTACGTCACACCCACGCCCTCAATGAGCGTGGCGCAGTTGCATCCCGATACGGAAGAAGGCGATCTGGCGAAAGG
ATTTACCGTCCCGCGCGACACAGCCTTTTTCTCCGCCATTCCGGAAGGCGAAAGCACTGCCTGCCAGTTTCGCAGCAGCC
AGGATGTAACGCTGTGGCCGCTCGCCATCGAAGAGGCGCGACTGACCGCCGCGCCACCGGATATGCCTGCCCTGCACCGC
TACCTGCCGGCCAACATTCACGTCGCCGGGGCGCTGCGTATTACCCTGCGCACCTTTGGTGAACTAACGTTCAGTCAGCT
TGCCGGACTGGACAGGCTGCCGTTTTATCTCTGCGGCGAGGAGCGTACGGCCTCACACCTGTTAGAACTTCTACATACCA
GCGCCATCGCGCCCCTGGCTGGCATTCCGGGGCATTTTGACGGCGCGCTGGATGTGAATCTGCAACAGCCCGTTATGTAC
GAAGGCCTGGAGCCGGATCAGGGGCTGCTGCCGCTGGCGTGGAACGTGTTTCACGGTCATAACCTGCTGCATGAATATTT
TGCCTGTCCGGAACGCTTCTATTTTTTCACCCCGACAGGCCTGTCTGCCGGATTACAGAAAATTGACGGTGGCGTGGCGG
AGATTGTTATCCTGCTGAACCGCCTGCCGCCGGACTGGCTGATCCACCAGACAAATGCGGCACAGTTCAGCCTGTTCTGT
ACCCCGGTTATCAACCTGTTTCCCCGCGTCACCGCCCGGATCGATGTCACGCACAGCACGACGGAACAGCATCTGGTGGT
GGACAGAACCCATCCGCTGGATTATGAGGTGTTCTCGGTCCAGGAAGTGGAAGGGCTGGAAACCGACACCACACGGAAGA
TGGCCTTTCGCCCGCTCTACCACACCCGCAATAATGATGAAGGCAATCACGGACGTTATTTTTCCCTGCGCCGGGAGCCC
CGCCGCTTATCAGAAAACGCCCGCCGTTACGGCACCCGTACCCCCTATACGGGCTCGGAAGTGTTCCTGTCGCTGGTTGA
CCAGTATGAAGCGCCGTACCCGGAAAATCTGCGCCACATCACCATCACGGCCATGGTCACTAACCGCGATCTGCCCTGTC
TTATTGCCCGCAATGGCCGGGACGATCTAACCGTGGATGCAGCCATCCCGGTGGCGGGCGTAGGGCTTATCCGCCCGCCA
CGCTCGCCGCAGCCCCCGATGGCTGAACGTGAGATGGCATGGCGGTTGATCCGCCAGTTATCTTTTAATTATCTGCCGCT
GGCCGATCTGGATCACCGTACCGGCGGCCAGGCGTTGCGAGATCTGCTGAACCTGTTTATTCCTGCTCATGACAGTCCGC
AATCGCGCCAGGTGCGCAGCCTGATTGGTTGTAAAACGACCCCGGTCACCCGCCGTCTGCCCGGTTCCGGACTACTGGTC
TATGGGCGTGGCGTCAGTTGTGAACTGACGGTGGATGAAGAAGGTTTTTCCGGCATCAGTCCGTATCTGTTCGGCCTGGT
GCTGGAACACTATATCGCCCGCCATGTTTCCATTAATACCTTCTCGCAGATGACGCTGCACAGCATGCAGCGCGGCAAAA
TTATGACCTGGCCTGTCAGGGCGGGACAGCGGGGAAGCGTATGA

Protein sequence :
MDPRLLEYYNRELSYLRETGAEFAARHPKVAARLGMQGTDIADPYVERMVEAFSFLTARTQLKIDAEFPRFTQRLLEVVS
PNYVTPTPSMSVAQLHPDTEEGDLAKGFTVPRDTAFFSAIPEGESTACQFRSSQDVTLWPLAIEEARLTAAPPDMPALHR
YLPANIHVAGALRITLRTFGELTFSQLAGLDRLPFYLCGEERTASHLLELLHTSAIAPLAGIPGHFDGALDVNLQQPVMY
EGLEPDQGLLPLAWNVFHGHNLLHEYFACPERFYFFTPTGLSAGLQKIDGGVAEIVILLNRLPPDWLIHQTNAAQFSLFC
TPVINLFPRVTARIDVTHSTTEQHLVVDRTHPLDYEVFSVQEVEGLETDTTRKMAFRPLYHTRNNDEGNHGRYFSLRREP
RRLSENARRYGTRTPYTGSEVFLSLVDQYEAPYPENLRHITITAMVTNRDLPCLIARNGRDDLTVDAAIPVAGVGLIRPP
RSPQPPMAEREMAWRLIRQLSFNYLPLADLDHRTGGQALRDLLNLFIPAHDSPQSRQVRSLIGCKTTPVTRRLPGSGLLV
YGRGVSCELTVDEEGFSGISPYLFGLVLEHYIARHVSINTFSQMTLHSMQRGKIMTWPVRAGQRGSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0289 NP_454871.1 hypothetical protein Not tested SPI-6 Protein 0.0 92

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
safC NP_835942.1 outer membrane usher protein VFG2074 Protein 4e-121 42