Gene Information

Name : S2184 (S2184)
Accession : NP_837625.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : ISSfl3 orfC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG3436
EC number : -
Position : 2065084 - 2066685 bp
Length : 1602 bp
Strand : +
Note : residues 1 to 533 of 533 are 97.37 pct identical to residues 1 to 533 of 533 from GenPept : >gb|AAL72472.1| (AF386526) hypothetical protein [Shigella flexneri 2a]

DNA sequence :
ATGAACAATGAACTCCCCGATGATATTGAGCTGCTTAAAGCCATGTTGCGTAAGCAACAGAGTCGGCTTCGACAGTATGC
CTGTCAGGTCGCGGGCTATGAGCAGGAAATTGAACGGCTGAAAGCGCAACTCGACAGGTTGCGTCGTATGTTGTTCGGCC
AGAGTTCAGAGAAAAAGCGTCATAAGCTTGAAAATCAGATCCGACAGGCAGAAAAACGACTGTCGGAACTGGAAAACCGG
CTGAACACAGCCAGAAATCTTCTGGAAGATGCATCGTCAGTCACAGATTCACCTGACACCAGTCCCCCGTCAGAAAACCC
GATCGCCAGTAAGCCTGAATTCCCGGGACGAAAATCTTCACGAAAACCGCTGCCGGCAGAACTTCCCCGGGAGACACATC
GCCTTCTGCCTGCTGAAACCAGTTGCCCGGCCTGTGGAGGTGTTCTGAAAGAAATGGGGGAAACAATCTCAGAGCAACTG
GATATCATTAATACCGCCTTTAAAGTTATCGAAACCATACGTCCCAAACTGGCCTGTAGCCGGTGTGATGTCATCGTTCA
GGCACCACTTCCCCCTAAACCGATCGAACGCGGTTATGCCAGTGCAGGGTTACTTGCACGGATCCTGGTCAGCAAATATA
TGGAACATATCCCTTTATATCGCCAGTCAGAAATATACGCGCGACAGGGCGTGGAGCTGAGCCGTAATACCATGGTGCGC
TGGGTATCAGAAATGGCAGACAAACTCCGTCCTCTGTATATAGCGCTGAATGACTATGTTCTGGAGGCAGGAAAGGTGCA
CGCAGATGACACTCCGGTGAAAGTACTGGCCCCGGGGAACGGAAAGACGAAAACGGGTCGTCTGTGGGTATACGTCAGGG
ATGATCGTAATGCGGGTTCATCCCTGCCGGCAGCCGTCTGGTTCGCGTATTCGGCAGATCGCAAAGGAGAACATCCGCAG
CTCCACCTGGCAAAGTATCAGGGCGTACTGCAGGCTGATGCCTATGCAGGTTATAACGTACTGTACGAAACGGGCCGGGT
GAAGGAAGCCGGGTGCCTGGCCCACGCCCGCCGAAAAACCCATGACGAGGATGTGCGCCGTCCGACAGAAATGACTCAGG
AAGCGCTCAGACGGATAGCAGAGTTATACGACATAGAAGCGGAGATACGTGGCAGTCCGGCAGAGGAACGGCTTGCAGTC
AGAAAAGCCAGAAGCGTCCAGTTGATGCAATCGTTGTACGACTGGATACAGTTGCAGAGGAAAACGCTGTCGAAACATGC
GGAGATGGCGAAGGCGTTCGACTATATCCTGAATCACTGGAATGCGCTGAACGAGTTCTGTCGTGACGGCTGGGTGGAAA
TAGACAACAACATCGGTGAAAACGCGTTACGATCGGTGGCGGTTGGAAGAAAAAATTATCTCTTTTTCGGCTCAGACAAG
GGAGGAGAAAGTGCGGCGATCATCTACAGTCTGCTGGTCACCTGCAAACAGAACGAAGTGGAGCCGGAGGACTGGTTGCG
CGAAGTGATCGAGAAGCTCAATGACTGGCCGTCGAACCAAGTGCATGAACTGCTGCCCTGGAACTTCTCGTCTGTAAAAT
AA

Protein sequence :
MNNELPDDIELLKAMLRKQQSRLRQYACQVAGYEQEIERLKAQLDRLRRMLFGQSSEKKRHKLENQIRQAEKRLSELENR
LNTARNLLEDASSVTDSPDTSPPSENPIASKPEFPGRKSSRKPLPAELPRETHRLLPAETSCPACGGVLKEMGETISEQL
DIINTAFKVIETIRPKLACSRCDVIVQAPLPPKPIERGYASAGLLARILVSKYMEHIPLYRQSEIYARQGVELSRNTMVR
WVSEMADKLRPLYIALNDYVLEAGKVHADDTPVKVLAPGNGKTKTGRLWVYVRDDRNAGSSLPAAVWFAYSADRKGEHPQ
LHLAKYQGVLQADAYAGYNVLYETGRVKEAGCLAHARRKTHDEDVRRPTEMTQEALRRIAELYDIEAEIRGSPAEERLAV
RKARSVQLMQSLYDWIQLQRKTLSKHAEMAKAFDYILNHWNALNEFCRDGWVEIDNNIGENALRSVAVGRKNYLFFGSDK
GGESAAIIYSLLVTCKQNEVEPEDWLREVIEKLNDWPSNQVHELLPWNFSSVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Z4317 NP_289543.1 hypothetical protein Not tested OI-122 Protein 1e-149 64
ECO103_3554 YP_003223421.1 hypothetical protein Not tested LEE Protein 3e-150 64
st57 CAC81895.1 ST57 protein Not tested LEE II Protein 4e-128 62
aec53 AAW51736.1 Aec53 Not tested AGI-3 Protein 4e-149 59
unnamed AAL57570.1 unknown Not tested LEE Protein 3e-134 56
unnamed CAI43806.1 hypothetical protein Not tested LEE Protein 3e-134 56
Z4340 NP_289564.1 hypothetical protein Not tested OI-122 Protein 6e-116 56
Z4337 NP_289562.1 hypothetical protein Not tested OI-122 Protein 2e-134 55
Z5098 NP_290249.1 prophage-associated protein Not tested LEE Protein 2e-134 55
unnamed AAC31494.1 L0015 Not tested LEE Protein 1e-134 55
unnamed CAC39285.1 hypothetical protein Not tested LPA Protein 1e-134 55
tnp AEA34686.1 transposase Not tested Not named Protein 1e-135 55
Z1131 NP_286666.1 hypothetical protein Not tested TAI Protein 9e-134 55
Z1570 NP_287074.1 hypothetical protein Not tested TAI Protein 9e-134 55
unnamed ACU09439.1 IS66 family element transposase Not tested LEE Protein 3e-134 55
ECs4547 NP_312574.1 hypothetical protein Not tested LEE Protein 4e-134 55
unnamed AAL08460.1 unknown Not tested SRL Protein 3e-96 53
Z1161 NP_286696.1 hypothetical protein Not tested TAI Protein 1e-117 51
Z1600 NP_287104.1 hypothetical protein Not tested TAI Protein 1e-117 51
BCAM0248 YP_002232880.1 putative transposase Not tested BcenGI11 Protein 2e-120 50
tnp AEA34687.1 IS66 family transposase Not tested Not named Protein 1e-74 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S2184 NP_837625.1 ISSfl3 orfC VFG0793 Protein 7e-135 55
S2184 NP_837625.1 ISSfl3 orfC VFG1051 Protein 2e-96 53
S2184 NP_837625.1 ISSfl3 orfC VFG1736 Protein 2e-97 52