Gene Information

Name : sitD (S1967)
Accession : NP_837468.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : Iron transport protein, inner membrane component
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 1904666 - 1905523 bp
Length : 858 bp
Strand : +
Note : residues 2 to 263 of 285 are 64.50 pct identical to residues 3 to 264 of 282 from GenPept : >emb|CAD05971.1| (AL627276) Iron transport protein, inner membrane component [Salmonella enterica subsp. enterica serovar Typhi]

DNA sequence : 
ATGATGGCATTATTACTGGAGCCACTGCAGTTCACCTTTATGAGTCACGCACTGCTGATTTCACTGGTAGTTTCCATACC
CTGTGCGCTGCTGTCGGTCTTTCTGGTCCTGAAAGGTTGGGCACTGATGGGTGACGCGATGAGTCATGCGGTTTTTCCTG
GCATCGTGCTTACCTGGATTCTGGGGTTACCTCTGGCTACAGGGGCATTCGTCGCCGGAGTATTCTGCGCGGTGGCGACG
GGATACCTGAAAGACAACAGCCGAATCAAGCAAGATACAGTTATGGGGATTGTTTTTTCTGGCATGTTTGCCGCAGGTCT
GATCTTGTATATTGCAATTAAACCAGACGTACATCTTGACCATATTCTTTTCGGCGACATGCTCGGGATAACCATCGGCG
ACATAATCCAGACGGTGATTATTGCCGGGCTGGTTACACTTGTTATTAGCGTAAAATGGCGGGATTTTTTGCTGTTCAGC
TTTGATTATCAACAGGCGCAGGTAAGCGGTTTGCATACGAGATGGCTGCATTATGGGCTGCTGTGCATGGTTTCCCTGAC
CATTGTGGCGACGCTGAAAGCAGTAGGTATCATTCTCTCTATTTCTCTGCTCATTGCGCCTGGCGCCATTGCAGTACTCC
TGACACAACGCTTTCATATTGCGCTCCTACTGGCGACTGGCATATCGGTAATAGTGTCAATGACTGGTGTCTGGCTGTCC
TTTTTTATCGACAGCGCACCAGCTCCGACGATTGTCGTCTTATTCGCGGTCGTGTTCATCATGACGTTTACCGTTACCAG
CATCAACGCACGCACAAAGGGAAACGCCCATACACAGGATCTGTTATCACCCAATTAG

Protein sequence : 
MMALLLEPLQFTFMSHALLISLVVSIPCALLSVFLVLKGWALMGDAMSHAVFPGIVLTWILGLPLATGAFVAGVFCAVAT
GYLKDNSRIKQDTVMGIVFSGMFAAGLILYIAIKPDVHLDHILFGDMLGITIGDIIQTVIIAGLVTLVISVKWRDFLLFS
FDYQQAQVSGLHTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAIAVLLTQRFHIALLLATGISVIVSMTGVWLS
FFIDSAPAPTIVVLFAVVFIMTFTVTSINARTKGNAHTQDLLSPN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 4e-76 68
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 3e-76 68
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 3e-76 68
sitD NP_461785.1 permease Virulence SPI-1 Protein 2e-76 68
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 1e-76 68

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitD NP_837468.1 Iron transport protein, inner membrane component BAC0352 Protein 8e-77 68
sitD NP_837468.1 Iron transport protein, inner membrane component BAC0442 Protein 6e-56 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitD NP_837468.1 Iron transport protein, inner membrane component VFG0528 Protein 7e-77 68