Gene Information

Name : sitC (S1966)
Accession : NP_837467.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : Iron transport protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 1903812 - 1904669 bp
Length : 858 bp
Strand : +
Note : residues 1 to 277 of 285 are 75.45 pct identical to residues 1 to 277 of 286 from GenPept : >gb|AAL21743.1| (AE008830) Salmonella iron transporter: fur regulated [Salmonella typhimurium LT2]

DNA sequence : 
ATGAACGTGCTACTGGAACCCTTCAGCTATGAATATATGCTCAATGCGATGTGGGTCTCGGCAATGGTCGGCGGTCTCTG
CGCTTTCCTGTCATGCTATCTGATGCTAAAAGGCTGGTCGCTGATTGGCGATGCGCTGTCGCACTCTATTGTCCCGGGTG
TTGCGGGGGCATATATGCTGGGGCTTCCGTTTTCTCTGGGAGCCTTCTTTTCCGGCGGACTGGCAGCGGGCAGCATGCTG
TTTCTTAACCAACGCACCCGCTTAAAAGAAGATGCCATCATCGGCCTGATCTTCTCGTCCTTTTTTGGCCTGGGGCTGTT
TATGGTGTCATTGAACCCGACATCCGTGAACATTCAGACCATCGTCCTGGGCAATATTCTGGCAATCGATCCGGCGGATA
TCCTGCAACTCACTATCATTGGCATTCTCTCGATCATCGTGCTTTTTTTCAAATGGAAAGATCTTATGGTGACCTTTTTC
GACGAGAATCACGCCCGTGCTATTGGATTACATCCGGGCAGATTAAAAATCCTCTTCTTCACCCTGCTGTCGGTTTCGAC
CGTTGCGGCGCTGCAAACGGTTGGTGCCTTTCTGGTGATCTGTCTGGTGGTGACTCCCGGTGCAACAGCATGGTTGTTAA
CCGATCGTTTTCCCCGCCTGCTCATAATTGCTGTAACTATTGGCAGTGTAACCAGTTTCCTCGGCGCGTGGGTCAGTTAC
TTTCTGGACGGCGCGACAGGTGGAATCATCGTGGTGGCGCAGACACTGCTGTTTCTTTTAGCATTTGTATTTGCGCCCAC
CCATGGACTTTTGGCAAATCGTCGGCGTGCGCATAAAGCGCTGGAGGATCGCTCATGA

Protein sequence : 
MNVLLEPFSYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSML
FLNQRTRLKEDAIIGLIFSSFFGLGLFMVSLNPTSVNIQTIVLGNILAIDPADILQLTIIGILSIIVLFFKWKDLMVTFF
DENHARAIGLHPGRLKILFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLIIAVTIGSVTSFLGAWVSY
FLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRRRAHKALEDRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-90 87
sitC NP_461784.1 permease Virulence SPI-1 Protein 1e-90 87
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 1e-90 87
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 1e-90 87
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 1e-90 87

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC NP_837467.1 Iron transport protein BAC0351 Protein 7e-91 87
sitC NP_837467.1 Iron transport protein BAC0441 Protein 2e-66 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC NP_837467.1 Iron transport protein VFG0527 Protein 6e-91 87