Gene Information

Name : sitB (S1965)
Accession : NP_837466.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : Iron transport protein, ATP-binding component
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1121
EC number : -
Position : 1902988 - 1903815 bp
Length : 828 bp
Strand : +
Note : residues 2 to 266 of 275 are 77.73 pct identical to residues 1 to 265 of 273 from GenPept : >emb|CAD05969.1| (AL627276) Iron transport protein, ATP-binding component [Salmonella enterica subsp. enterica serovar Typhi]

DNA sequence : 
ATGATGCAATCTGCAGGCATTGTCGTTAATGATGTTACTGTCACCTGGCGTAACGGGCACACAGCACTGCGCGATGCATC
CTTCACAGTACCAAGTGGATCTATTGCCGCTCTGGTTGGGGTAAACGGTTCCGGAAAATCGACGTTGTTTAAAGCGATTA
TGGGATTTGTGCGTCTGACCAGCGGAAAGATATCTGTTCTGGGTATTCCCACGCGACAGGCGCTACAGAAAAACCTGGTT
GCCTACGTCCCTCAGTCAGAAGAGGTTGACTGGTCATTTCCTGTACTGGTGGAAGATGTGGTGATGATGGGCCGCTATGG
GCATATGGGTATGTTGCGTATAGCCAAAAAGAGGGATCGTCAGATTGTCACCGATGCGCTGGAACGTGTCGATATGGTGG
ATTTTCGCCATCGTCAAATCGGCGAGCTTTCCGGTGGACAAAAGAAACGCGTCTTTCTGGCGAGAGCAATTGCACAGCAG
GGTGATGTGATCCTGCTGGATGAACCTTTTACCGGCGTTGATGTGAAAACCGAAGCGAAAATCATCAGCCTGTTGAGGGA
GTTAGGGAGCGAAGGCAAAACGATGCTTGTCTCAACGCACAATCTCGGCTCAGTCACGACATTTTGCGATTATACGGTCA
TGGTCAAAGGCACCGTCCTGGCAAGCGGGCCGACAGACACCACTTTTACAGCCGAGAACCTGGAGCTGGCTTTTAGCGGC
GTACTGCGCCATGTCACACTTAACGGCTCGGAAGAAAGCATTATTACTGACGATGAACGCCCTTTTGTGGCACATCGACC
GTCAGCGGTGCAGAGGGAAGCAAGATGA

Protein sequence : 
MMQSAGIVVNDVTVTWRNGHTALRDASFTVPSGSIAALVGVNGSGKSTLFKAIMGFVRLTSGKISVLGIPTRQALQKNLV
AYVPQSEEVDWSFPVLVEDVVMMGRYGHMGMLRIAKKRDRQIVTDALERVDMVDFRHRQIGELSGGQKKRVFLARAIAQQ
GDVILLDEPFTGVDVKTEAKIISLLRELGSEGKTMLVSTHNLGSVTTFCDYTVMVKGTVLASGPTDTTFTAENLELAFSG
VLRHVTLNGSEESIITDDERPFVAHRPSAVQREAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitB NP_457256.1 Iron transport protein, ATP-binding component Virulence SPI-1 Protein 6e-101 76
sitB NP_806465.1 iron ABC transporter ATP-binding protein Virulence SPI-1 Protein 6e-101 76
sitB AAD41066.1 SitB Virulence centisome 63 pathogenicity island Protein 5e-100 75
sitB NP_461783.1 ATP-binding protein Virulence SPI-1 Protein 7e-100 75
sitB YP_217782.1 iron transporter: fur regulated Virulence SPI-1 Protein 5e-100 75

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitB NP_837466.1 Iron transport protein, ATP-binding component BAC0350 Protein 3e-100 75
sitB NP_837466.1 Iron transport protein, ATP-binding component BAC0440 Protein 1e-79 61
sitB NP_837466.1 Iron transport protein, ATP-binding component BAC0400 Protein 7e-45 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitB NP_837466.1 Iron transport protein, ATP-binding component VFG0526 Protein 3e-100 75