Gene Information

Name : sitA (S1964)
Accession : NP_837465.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Virulence
Product : Iron transport protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 1902098 - 1902988 bp
Length : 891 bp
Strand : +
Note : residues 16 to 296 of 296 are 79.35 pct identical to residues 24 to 304 of 305 from GenPept : >gb|AAL21741.1| (AE008830) Salmonella iron transporter: fur regulated [Salmonella typhimurium LT2]

DNA sequence : 
ATGCTCTTGGGGTGCCTCGCCCTCACCTGCTCGATCGCATTTCAGGCAAGTGCAACTGAAAAATTCAAGGTCATTACAAC
ATTTACCATCATCGCGGATATGGCCAAAAACGTGGCTGGAGATGCTGCAGAAGTCTCATCCATAACCAAGCCTGGTGCAG
AAATTCATGAGTATCAGCCTACCCCTGGCGATATTAAACGTGCGCAGGGGGCACAACTGATTCTCGCCAATGGTATGAAT
CTGGAATTGTGGTTCCAACGCTTTTACCAGCATCTCAATGGGGTTCCAGAAGTAATTGTCTCTTCGGGTGTGACGCCAGT
AGGGATCACCGAAGGACCCTATGAGGGCAAACCTAATCCCCATGCATGGATGTCGCCAGATAATGCTCTGATTTACGTCG
ATAATATTCGTGATGCGTTGATAAAATACGATCCGGCAAATGCACAAACCTACCAACGTAATGCCGATACTTATAAAGCC
AAGATTACCCAAACCCTTGCCCCCCTGCGTAAGCAGATTACGGAACTCCCTGAGAATCAGCGATGGATGGTCACCAGTGA
AGGGGCTTTTTCTTATCTCGCACGCGATTTGGGGCTAAAAGAGCTTTATCTGTGGCCGATTAATGCCGATCAACAAGGAA
CACCGCAGCAGGTACGTAAGGTTGTTGATATAGTTAAGAAAAATCATATCCCGGCAGTCTTTAGCGAGAGTACGATTTCC
GATAAACCAGCGCGTCAGGTTGCGCGTGAAACCGGCGCACACTACGGCGGTGTGCTCTATGTCGATTCCCTGAGCACAGA
AAACGGCCCGGTACCTACGTATATCGACCTTCTTAAGGTTACTACCAGTACGCTGGTACAGGGAATTAAAGCCGGGAAAA
GGGAGAAATAA

Protein sequence : 
MLLGCLALTCSIAFQASATEKFKVITTFTIIADMAKNVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGMN
LELWFQRFYQHLNGVPEVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAQTYQRNADTYKA
KITQTLAPLRKQITELPENQRWMVTSEGAFSYLARDLGLKELYLWPINADQQGTPQQVRKVVDIVKKNHIPAVFSESTIS
DKPARQVARETGAHYGGVLYVDSLSTENGPVPTYIDLLKVTTSTLVQGIKAGKREK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 1e-110 80
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 1e-110 80
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 8e-111 80
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-110 80
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 1e-110 80

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA NP_837465.1 Iron transport protein BAC0349 Protein 5e-111 80
sitA NP_837465.1 Iron transport protein BAC0439 Protein 8e-91 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitA NP_837465.1 Iron transport protein VFG0525 Protein 4e-111 80