Gene Information

Name : malX (S1778)
Accession : NP_837307.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : bifunctional maltose and glucose-specific PTS system components IICB
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG1263
EC number : -
Position : 1715709 - 1717301 bp
Length : 1593 bp
Strand : +
Note : phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC

DNA sequence :
ATGACGGCGAAAACAGCACCGAAAGTCACGCTGTGGGAGTTCTTCCAGCAGTTAGGCAAAACCTTCATGTTACCCGTGGC
ATTATTGTCGTTCTGCGGCATTATGCTCGGCATTGGTAGTTCTCTTAGCAGCCATGATGTCATAACCCTGATCCCGGTCC
TGGGCAACCCCGTGTTGCAGGCTATCTTTACCTGGATGAGTAAGATTGGCTCGTTTGCTTTTAGTTTCCTGCCTGTCATG
TTCTGTATCGCCATCCCGCTGGGCCTGGCACGCGAAAATAAAGGCGTAGCGGCATTCGCTGGCTTCGTCGGTTATGCGGT
AATGAACCTCGCGGTAAACTTCTGGTTGACCAATAAAGGCATTCTGCCAACCACAGATGCCGCCGTTCTGAAAGCCAATA
ACATCCAGAGCATTCTTGGGATCCAGTCGATCGATACCGGGATCCTCGGTGCGGTGATCGCCGGTATTATCGTCTGGATG
CTGCATGAGCGTTTCCATAATATCCGCCTGCCGGATGCGCTGGCATTCTTCGGCGGTACGCGCTTCGTACCAATTATCTC
CTCGCTGGTGATGGGCCTTGTCGGCCTGGTGATTCCATTAGTCTGGCCGATTTTCGCCATGGGTATTAGCGGCTTGGGCC
ATATGATAAACAGCGCGGGTGATTTCGGACCGATGCTGTTTGGTACCGGTGAACGTCTGCTGTTGCCGTTTGGTCTGCAT
CACATTCTGGTGGCATTAATTCGCTTTACCGACGCAGGCGGCACGCAGGAGGTCTGCGGTCAAACCGTCAGCGGCGCACT
GACCATCTTCCAGGCGCAATTGAGTTGCCCGACCACTCACGGTTTTTCTGAAAGCGTCACGCGTTTCCTTTCGCAAGGTA
AAATGCCTGCGTTTCTCGGCGGTCTACCAGGTGCAGCGTTAGCTATGTATCACTGCGCGCGCCCGGAAAATCGCCATAAA
ATTAAAGGTCTGCTGATTTCTGGCCTGATCGCCTGCGTCGTTGGCGGCACTACCGAACCGCTGGAATTCCTGTTCCTGTT
CGTAGCGCCAGTTCTGTATGTCATCCACGCGCTGTTAACCGGCCTCGGCTTCACCGTCATGTCTGTGCTCGGCGTCACCA
TCGGTAATACCGACGGCAATATCATCGACTTCGTGGTGTTCGGTATTTTGCATGGTCTGTCAACCAAGTGGTACATGGTG
CCAGTGGTGGCGGCAATCTGGTTTGTCGTTTACTACGTCATCTTCCGTTTCGCTATCACCCGCTTCAATCTGAAAACCCC
GGGGCGCGATAGCGAAGTTGCCAGCTCAATCGAAAAAGCCGTTGCCGGTGCGCCGGGTAAATCAGGTTACAACGTTCCTG
CAATCCTCGAAGCATTAGGCGGTGCCGACAATATTGTCAGCCTCGATAACTGCATTACCCGTCTGCGTTTGTCTGTGGAA
GATATGTCGCTTGTTAATGTGCAGGCGGTGAAGGACAATCGGGCAATTGGCGTAGTACAACTTAATCAACATAACCTGCA
GGTTGTTATCGGGCCACAAGTTCAGTCAGTAAAAGATGAAATGGCCGGTCTGATGCATACTGTCCAGGCATAA

Protein sequence :
MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVM
FCIAIPLGLARENKGVAAFAGFVGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGERLLLPFGLH
HILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESVTRFLSQGKMPAFLGGLPGAALAMYHCARPENRHK
IKGLLISGLIACVVGGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMV
PVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCITRLRLSVE
DMSLVNVQAVKDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61292.1 MalX homolog Not tested PAI I CFT073 Protein 1e-75 42
malX AAC61732.1 MalX Not tested PAI I CFT073 Protein 1e-75 42