Gene Information

Name : nadE (S1603)
Accession : NP_837164.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 1560542 - 1561369 bp
Length : 828 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
ATGACATTGCAACAACAAATAATAAAGGCGCTGGGCGCAAAACCGCAGATTAATGCTGAAGAGGAAATTCGTCGTAGTGT
CGATTTTCTGAAAAGCTACCTGCAAACTTATCCGTTCATTAAATCACTGGTGCTCGGGATCAGCGGCGGTCAGGACTCCA
CGCTTGCCGGAAAGCTGTGCCAGATGGCGATTAATGAGCTGCGCCAGGAAACTCGCAACGAATCACTGCAATTTATTGCC
GTACGCCTGCCCTATGGTGTTCAGGCTGACGAACAAGATTGCCAGGATGCCATTGCCTTTATTCAACCGGATCGCGTATT
AACCGTTAATATCAAGGGCGCGGTATTGGCTAGCGAGCAGGCATTGCGGGAAGCAGGCATTGAACTGAGCGATTTTGTCC
GTGGCAATGAAAAAGCGCGTGAGCGGATGAAAGCACAATATAGCATTGCGGGTATGACCAGCGGTGTCGTGGTGGGCACC
GATCATGCAGCAGAAGCCATTACCGGATTCTTCACTAAATATGGTGACGGCGGTACGGATATTAATCCGCTGTATCGTCT
CAACAAACGCCAGGGTAAACAGTTACTGACGGCATTAGGTTGCCCGGAACACCTTTATAAGAAAGCCCCAACTGCCGATC
TTGAAGATGATCGCCCTTCTCTGCCAGATGAAGTGGCACTCGGCGTGACCTATGACAATATCGACGACTATCTGGAAGGG
AAAAACCTACCTGAACAGGTCGCCAGAACAATAGAGAACTGGTATCTGAAAACCGAACATAAACGCCGTCCGCCAATTAA
CGTTTTCGATGATTTCTGGAAAAAGTAA

Protein sequence :
MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETRNESLQFIA
VRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLTALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEG
KNLPEQVARTIENWYLKTEHKRRPPINVFDDFWKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 1e-60 54