Gene Information

Name : S1127 (S1127)
Accession : NP_836753.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : IS911 orfB
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG2801
EC number : -
Position : 1099436 - 1100113 bp
Length : 678 bp
Strand : +
Note : residues 1 to 225 of 225 are 100.00 pct identical to residues 55 to 279 of 279 from GenPept : >gb|AAL72449.1| (AF386526) InsB [Shigella flexneri 2a]

DNA sequence :
ATGGCAACCCGGAGAGGCTACCAGATGGGACGCTGGCTTGCTGGCAGGCTCATGAAAGAGCTGGGGCTGGTCAGCTGTCA
GCAGCCGACTCACCGGTATAAACGTGGTGGTCATGAACATGTTGCTATCCCTAACTACCTTGAAAGGCAGTTCGCCGTGA
CCGAGCCAAATCAGGTGTGGTGCGGTGATGTGACCTATATCTGGACGGGTAAGCGCTGGGCGTACCTCGCCGTTGTTCTC
GACCTGTTCGCAAGAAAACCAGTGGGCTGGGCCATGTCGTTCTCGCCGGACAGCAGGCTCACCATGAAAGCGCTGGAAAT
GGCATGGGAAACCCGTGGTAAGCCCGGCGGGGTGATGTTCCACAGCGATCAGGGCAGTCATTATACGAGCAGGCAGTTCC
GGCAGTTATTGTGGCGATACCAGATCAGACAGAGTATGAGCCGGCGCGGAAACTGCTGGGATAACAGCCCAATGGAACGC
TTCTTCAGGAGTCTGAAGAACGAATGGATGCCGGTGGTGGGTTACGTAAGCTTCAGCGAGGCAGCTCACGCCATAACGGA
CTATATCGTTGGATATTACAGTGCACTAAGACCGCACGAATATAACGGTGGGTTACCCCCAAACGAATCGGAAAATCGAT
ACTGGAAAAACTCTAACTCGGTGGCCAGTTTTTGTTGA

Protein sequence :
MATRRGYQMGRWLAGRLMKELGLVSCQQPTHRYKRGGHEHVAIPNYLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVL
DLFARKPVGWAMSFSPDSRLTMKALEMAWETRGKPGGVMFHSDQGSHYTSRQFRQLLWRYQIRQSMSRRGNCWDNSPMER
FFRSLKNEWMPVVGYVSFSEAAHAITDYIVGYYSALRPHEYNGGLPPNESENRYWKNSNSVASFC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
l7094 CAD33743.1 ORF B protein Not tested PAI I 536 Protein 1e-97 90
orfB CAE85178.1 OrfB protein, IS911 Not tested PAI V 536 Protein 1e-97 90
orfB AGK06910.1 IS1359 transposase; OrfB Not tested SGI1 Protein 1e-80 70
overlap with orfA characteristic of IS3 family members AGK06947.1 IS1359 transposase; OrfB Not tested SGI1 Protein 1e-80 70
orfB AGK06993.1 IS1359 transposase; OrfB Not tested SGI1 Protein 1e-80 70
orfB AGK07051.1 IS1359 transposase; OrfB Not tested SGI1 Protein 1e-80 70
VC1789 NP_231424.1 transposase OrfAB subunit B Not tested VPI-2 Protein 2e-80 70
orfB ACX47958.1 IS1359 transposase; OrfB Not tested SGI1 Protein 1e-80 70
orfB YP_001217329.1 transposase OrfAB subunit B Not tested VPI-2 Protein 2e-80 70
VPI2_0008c ACA01825.1 transposase OrfAB subunit B Not tested VPI-2 Protein 1e-80 70
unnamed CAI43898.1 putative transposase Not tested LEE Protein 6e-66 63
aec65 AAW51748.1 Aec65 Not tested AGI-3 Protein 6e-66 63
ECO111_3779 YP_003236114.1 putative IS602 transposase OrfB Not tested LEE Protein 5e-66 63
ECs4537 NP_312564.1 hypothetical protein Not tested LEE Protein 3e-65 62
unnamed AAC31485.1 L0006 Not tested LEE Protein 2e-65 62
Z5089 NP_290241.1 transposase Not tested LEE Protein 3e-66 61
unnamed ACU09432.1 IS911 transposase orfB Not tested LEE Protein 2e-66 61
RS04 AAP82949.1 putative transposase Not tested PAPI-2 Protein 5e-56 57
tnpB CAB61574.1 transposase B Not tested HPI Protein 4e-36 45
trp1329B CAB46576.1 IS1329 transposase B Not tested HPI Protein 3e-35 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S1127 NP_836753.1 IS911 orfB VFG1484 Protein 7e-98 90
S1127 NP_836753.1 IS911 orfB VFG1122 Protein 6e-81 70
S1127 NP_836753.1 IS911 orfB VFG0785 Protein 9e-67 61