Gene Information

Name : BC5227 (BC5227)
Accession : NP_834890.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 5130203 - 5131963 bp
Length : 1761 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAAACAATCTGTTTCAGCTGAGCAAATTGAATTGAAATCGAGTTTACCAGGGAGTAAGAAAGTATATGTGGATGGACC
ACGAGAAGGCATGAAAGTACCGATGCGTGAGATTGAACAAAGCGAAACGAATGGCGTTCCAAATCCGCCAATTCGTGTGT
ATGATACGAGCGGCCCTTATACGGATCCTGAGTATAAAGTGGAGTTAGAAAAGGGGATTCCAACGCCGCGCCATTCTTGG
ATTCTGGGGCGTGGTGATGTAGAAGCATACGAAGGGCGTGAAGTGAAACCAGAGGATGACGGTGTGAAAGTGGCTTCGAA
ACATACACCTGTTTTCCCGCAGATGGATCGCAAGCCACTTAGAGCAAAGCAAGGTGCAAACGTTACGCAAATGCACTATG
CACGTAATGGCATTATTACGTCTGAGATGGAGTATGTTGCGATTCGTGAAGGGGTAGAGCCGGAGTTTGTTCGTAAGGAA
ATCGCAGAAGGCCGCGCTATTTTACCAGCGAATATTAATCATCCAGAAGCTGAACCGATGATCATCGGGCGTAATTTCCA
TGTGAAGGTAAACGCGAATATCGGAAACTCAGCTGTATCTTCTTCGATTGCAGAAGAAGTAGAGAAGATGACATGGGCAA
CGCGCTGGGGTGCAGATACGATTATGGATTTATCTACAGGTAAAAATATTCATACGACGCGTGAGTGGATTATTCGTAAC
GCGCCTGTACCAGTTGGAACTGTACCGATTTATCAAGCGCTGGAAAAAGTAAACGGAATTGCAGAAGATTTAACGTGGGA
AGTATATCGTGATACGTTAATTGAGCAGGCGGAGCAAGGCGTTGATTACTTTACAATTCACGCTGGTGTATTGCTTCGTT
ACATTCCAATCACGGCAAAGCGTACGACAGGTATCGTTTCGCGCGGTGGTTCGATTATGGCGCAGTGGTGTTTATTCCAT
CATAAAGAAAACTTCCTATATACTCATTTTGAAGAGATTTGTGAAATTATGAAGCAGTACGATGTTTCGTTCTCTCTTGG
AGATGGATTACGTCCAGGATCGATTGCAGATGCAAATGACGAAGCACAATTCTCTGAGCTTGAAACACTTGGTGAATTAA
CCAAAATTGCTTGGAAACATGATGTGCAAGTTATGATCGAAGGACCTGGACACGTACCGATGCACTTAATTAAAGAGAAT
ATGGAGAAAGAGCTTGATATTTGTCAGGGCGCGCCGTTTTATACACTTGGGCCACTAACGACAGATATTGCACCAGGTTA
TGACCATATTACATCGGCGATTGGAGCTGCTATGATTGGCTGGTTTGGAACAGCGATGCTTTGTTATGTAACGCCGAAAG
AACATTTAGGTTTGCCAAACAAAGATGATGTACGCACGGGTGTTATTACGTACAAAATTGCAGCGCATGCGGCTGATCTT
GCGAAAGGACATAAAACGGCTCATCAGCGTGATGATGCACTTTCAAAAGCACGCTTCGAATTCCGTTGGCGCGATCAATT
TAATTTATCTTTAGATCCTGAACGTGCGATGGAATATCATGATGAAACGTTGCCTGCAGAAGGGGCAAAGACAGCTCACT
TCTGTTCAATGTGTGGACCGAAGTTTTGTAGTATGAGAATTTCACATGATATTCGTGAGTATGCAAAAGAAAATGATTTA
GAAACGACAGAAGCAATTGAAAAAGGAATGAAAGAGAAAGCAGAAGAATTTAAAGAAGCTGGTAGTCATTTATATCAATA
A

Protein sequence :
MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSETNGVPNPPIRVYDTSGPYTDPEYKVELEKGIPTPRHSW
ILGRGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKE
IAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRN
APVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFH
HKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKEN
MEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVRTGVITYKIAAHAADL
AKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDL
ETTEAIEKGMKEKAEEFKEAGSHLYQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 66