Gene Information

Name : smpB (BC5128)
Accession : NP_834796.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 5030784 - 5031251 bp
Length : 468 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGCCAAAGGGTACAGGTAAGGTTATTGCACAGAACAAAAAAGCATTTCATGATTATTTCATCGAAGAAACATACGAAGC
AGGGCTTGTCCTTCAAGGAACGGAAATTAAGTCGATTCGCGCTGGACGCGTAAACTTGAAAGATGCGTTTGCACGTGTAC
ATAATGGTGAAGTATGGGTTCATAATATGCACATTAATACGTACGAACAAGGGAATCGTTTCAACCATGATCCACTTCGT
ACGAGAAAATTACTTCTGCATAAAAAAGAAATTGATAAACTAGCGGGCGCTGCGAAAGAAACAGGTTACGCATTAGTTCC
ACTTAGAATTTATTTGAAAAATGGATTTGCAAAGATGGCACTTGGTTTAGCAAAAGGTAAGAAGCAATACGATAAACGTC
ACGATTTAAAAGAGAAAGAAGCTAAACGTGAAATTGCACGCGCGTTCCGTGATCGCCAAAAGATGTAA

Protein sequence :
MPKGTGKVIAQNKKAFHDYFIEETYEAGLVLQGTEIKSIRAGRVNLKDAFARVHNGEVWVHNMHINTYEQGNRFNHDPLR
TRKLLLHKKEIDKLAGAAKETGYALVPLRIYLKNGFAKMALGLAKGKKQYDKRHDLKEKEAKREIARAFRDRQKM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 4e-38 64
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-29 50
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 3e-19 42