Gene Information

Name : leuS (BC4737)
Accession : NP_834441.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 4670353 - 4672761 bp
Length : 2409 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCTTTAATCATCAAGAAATTGAGAAGAAGTGGCAAGGGTACTGGGAAGAGAATAAAACATTCCGTACGCCAGATGA
GACAGAAAAACCAAAATTTTATGCACTAGATATGTTCCCATATCCATCAGGTGCAGGCTTACACGTAGGACATCCAGAAG
GTTATACAGCGACAGATATTTTATCTCGTATGAAGCGTATGCAAGGATATAACGTTCTGCATCCAATGGGATGGGATGCA
TTTGGTCTTCCAGCAGAGCAATATGCACTTGATACTGGAAACAGCCCAGCTGAATTTACAGAGCATAATATTAATACATT
CCGTAACCAAATTAAATCATTAGGTTTCTCTTACGATTGGGACCGTGAAGTAAATACAACAGATCCAAACTACTATAAGT
GGACGCAATGGATCTTCCTAAAACTATTTGAAAAAGGCTTAGCTTACGTTGATGAAGTACCTGTAAACTGGTGCCCAGCA
CTTGGTACAGTACTTGCAAACGAAGAAATCATTGACGGTAAGAGTGAGCGTGGTGGACATCCAGTTGAGCGTCGTCCGAT
GAGACAGTGGATGTTAAAAATTACAGCTTACGGAGATCGTCTATTAGAAGATCTAGATGAGCTTGATTGGCCTGAAAGCT
TAAAAGATATGCAACGTAACTGGATCGGTCGTTCTGAAGGTGCAGAAGTACACTTCAACATCGATGGTACAGACGAGAAA
TTCACAGTTTTCACAACGCGCCCTGATACATTATTTGGTGCAACATACTGTGTACTAGCTCCAGAACATGCACTTGTTGC
AGAAATTACAACAGCAGAACAAAAAGAAGCGGTAGAAGCTTACATTAACGCTGTAAAAATGAAGAGTGACCTAGAGCGTA
CAGAACTTGCGAAAGAGAAAACTGGTGTATTCACTGGTGCTTACGCAGTTAACCCAGTAAACGGTGAGAAATTACCAATC
TGGATCGCTGACTATGTTCTTGCAACTTACGGAACAGGTGCTGTAATGGCAGTTCCAGCTCACGATGAGCGTGACTATGA
ATTCGCATCAGTATTTAATCTTCCAATGAAGGAAGTTGTAAAAGGCGGAGATATTACGAAAGAAGTGTACACAGGTGATG
GTGCACACGTAAACTCAGCATTCCTTGATGGATTAAATAAAGAAGAAGCAATCGCAAAAATGATTGAATGGCTTGAAGCA
ACGAGCGCAGGAAATCAAAAAGTAACGTACCGTCTACGTGACTGGTTATTCAGCCGTCAACGTTACTGGGGTGAACCAAT
TCCAGTAATTCACTGGGAAGATGGTACAATGACAGCTGTGAAAGAAGAGGAATTACCATTAGTTCTTCCGAAAACAGAAA
ACATCCGTCCTTCAGGTACAGGTGAATCACCACTTGCTAACATTGACGAGTGGGTAAATGTTGTTGATCCTGAGACTGGT
AAAAAAGGTCGTCGTGAAACGAACACAATGCCGCAATGGGCTGGTAGCTGCTGGTACTACCTACGTTACATCGATCCAAA
CAATAGCGAAGCACTTGTAGATCCTGAAAAAGTAAAACAATGGCTTCCAGTTGATATTTATATCGGTGGTGCAGAACATG
CCGTACTTCACTTACTATATGCTCGTTTCTGGCATAAAGTATTATACGATATCGGTGTAGTTCCAACGAAAGAGCCATTC
CAACAATTATTCAACCAAGGTATGATTCTAGGTGAAAACAACGAGAAAATGAGTAAATCAAAAGGTAACGTTGTAAATCC
TGATGATATCGTAGCAAGCCACGGTGCAGATACACTTCGTCTATACGAAATGTTCATGGGACCATTAGATGCTTCAATTG
CTTGGTCTGAAAATGGTCTTGACGGAGCTCGTCGTTTCCTAGACCGCGTATGGCGTCTATTCGTTCAAGATAACGGTGAA
TTAAGTGAGAAAATTACTGACGCACCAAATAAAGAGCTTGAAAAAGCTTACCATCAAACAGTGAAGAAAGTAACAGAAGA
CTATGCAGAGCTTCGCTTCAACACAGCGATTTCTCAAATGATGGTATTCATCAACGATGCATACAAAGCTGAAACACTTC
CGAGAGAATATGTAGAAGGTTTCGTAAAAATGATTGCACCAGTTGCACCTCATATCGGGGAAGAGCTATGGAGCAAACTT
GGATACAATGAAACAATCACATATGCAAGCTGGCCAACATTTGATGAGTCTAAACTTGTAGAAGATGAAGTTGAAATTGT
TGTTCAAGTTATGGGTAAAGTTCGTGCAAAACTAACAATGAGTAAAGACGCATCAAAAGAAGAAATGGAACAACTTGCAC
TTGAAGCAATTCAAGACCAAATTGAAGGGAAAACAGTTCGTAAAGTAATTGTTGTTCCTGGAAAACTTGTTAATGTTGTT
GCAAATTAA

Protein sequence :
MSFNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPA
LGTVLANEEIIDGKSERGGHPVERRPMRQWMLKITAYGDRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDEK
FTVFTTRPDTLFGATYCVLAPEHALVAEITTAEQKEAVEAYINAVKMKSDLERTELAKEKTGVFTGAYAVNPVNGEKLPI
WIADYVLATYGTGAVMAVPAHDERDYEFASVFNLPMKEVVKGGDITKEVYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEA
TSAGNQKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETG
KKGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPF
QQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQDNGE
LSEKITDAPNKELEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAYKAETLPREYVEGFVKMIAPVAPHIGEELWSKL
GYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLTMSKDASKEEMEQLALEAIQDQIEGKTVRKVIVVPGKLVNVV
AN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 67