Gene Information

Name : BC4654 (BC4654)
Accession : NP_834360.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 4595394 - 4596569 bp
Length : 1176 bp
Strand : -
Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine

DNA sequence : 
ATGAAAAAGAAGCATATGGAGACAGCGTTAATTCATCACGGTTATAAACCTGAGGAATATAAAGGAAGTTTAACACCACC
TTTATTTCAAACTTCTACATTTACATTTGAGACTGCGCAGCAAGGAGAGGCGAGTTTTGCGGGAGTGGATCCATCTTATA
TTTACTCACGGCTTGGAAATCCAACTGTGAAATTATTTGAAGAACGTATGGCGGTGTTAGAAGGAGGAGAAGAGGCACTT
GCCTTCGGGTCTGGTATGGCAGCTATTTCAGCGACTTTAATCGGTTTTTTAAAGGCTGGAGATCATATTATTTGTTCAAA
TGGATTATACGGATGCACGTACGGTTTTTTAGAAGTGTTAGAAGAAAAATTTATGATTACGCATTCGTTTTGTGATATGG
AGACAGAGGCTGATATTGAAAATAAAATTCGCTCAAATACAAAGCTTATTTTCGTTGAAACACCAATTAATCCAACGATG
AAATTAATTGATTTAAAACAAGTGATTCGGGTTGCGAAGCGAAAAGGCTTACTTGTTATTGTTGATAATACATTTTGTTC
ACCTTATTTACAAAGACCGCTTGAGCTTGGCTGTGACGCTGTTGTGCATAGTGCGACAAAATATATTGGTGGTCACGGTG
ACGTTGTAGCGGGCGTAACAATTTGTAAAACGAAAGCATTAGCTGAAAAGATTCGCCCGATGCGAAAGGATATCGGCGGT
ATTATGGCACCGTTTGATGCGTGGTTATTATTACGCGGGTTAAAGACGTTAGCAGTAAGAATGGATCGTCATTGTGATAA
TGCAGAAAAAATTGTATCGTTCTTAAGAAAACATGATGCGGTAGAAGGTGTTTGGTATCCAGAAGGAGAGTTAGCATCTC
GTCAAATGAAACGCGGGGGCGGTGTTATTTCTTTTTCAGTAAAAGGCGGAAAAGAAGAGACGCAAGCGTTTATTAATGAT
CTTCACTTTATTACAATTGCGGTGAGTTTAGGAGATACAGAAACGTTAATTCAGCATCCAGCAACGATGACGCACGCTGC
GATTCCAGCTGAACTAAGAAAAGAAATGGGCATTTTCGATAATTTAATACGCTTATCAGTCGGTTTAGAATCGTGGGAGG
ATATCGTTTCTGATTTAGAGCAGGCATTAAAGAAAATATCTACTGTTAATCAATAA

Protein sequence : 
MKKKHMETALIHHGYKPEEYKGSLTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEAL
AFGSGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRSNTKLIFVETPINPTM
KLIDLKQVIRVAKRKGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTKALAEKIRPMRKDIGG
IMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLRKHDAVEGVWYPEGELASRQMKRGGGVISFSVKGGKEETQAFIND
LHFITIAVSLGDTETLIQHPATMTHAAIPAELRKEMGIFDNLIRLSVGLESWEDIVSDLEQALKKISTVNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-66 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-67 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BC4654 NP_834360.1 methionine gamma-lyase BAC0207 Protein 4e-89 48