Gene Information

Name : BC4599 (BC4599)
Accession : NP_834305.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 4545226 - 4546983 bp
Length : 1758 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGCGTAAAACTAAAATTGTATGTACTATAGGTCCTGCTAGTGAAAGTATTGAAAAATTAGAGCAATTAATCGAAGCAGG
TATGAACGTTGCTCGTTTAAACTTCTCTCATGGTAGCCATGAAGAGCACGGAGCTCGTATTAAAAACATTCGTGAAGCTT
CAAAGAAAACTGGTAAAACAGTTGGTATCTTACTTGATACAAAAGGTCCAGAAATCCGTACTCACGACTTCGTAGACGGA
CAAGCTGAGCTTGTAACAGGTGCAGAAGTAGTTCTTTCTACTGAGCAAGTATTAGGTACTGCAGAGAAGTTCTCTGTATC
TTATGCTGGTCTTTATGACGATGTAGACCCAGGTTCTCGTATTCTAATCGATGACGGTCTTATCGAACTAGAAGTAATCG
AAAAAGCTGATGGAAACATCCGTACAAAAGTTCTTAACAGCGGAACTGTAAAAAATAAAAAAGGTGTTAACGTACCAAAC
GTAAGCATTAAGCTTCCTGGTATCACTGAAAAAGACGTAAAAGATATCATCTTCGGTATCGAGCAAAAAGTTGATTTCAT
TGCAGCTTCATTCGTACGTAAAGCGTCTGACGTATTAGAAATCCGTGAATTATTAGAAGAGCATAACGCTCAATACATCC
AAATCGTACCAAAAATCGAGAACCAAGAAGGTATCGACAACATCGATTCAATCTTAGAAGTTTCTGACGGTTTAATGGTA
GCTCGTGGTGACATGGGTGTAGAAATTCCACCAGAAGAAGTACCGTTAGTACAAAAACGTCTAATTAAAAAATGTAACGT
GTTAGGTAAACCAGTTATTACTGCAACACAAATGTTAGATTCTATGCAACGTAACCCACGTCCAACTCGTGCGGAAGCAA
GTGACGTAGCTAACGCAATCTTCGATGGTACAGATGCAATCATGCTTTCAGGTGAAACAGCTGCTGGACAATACCCAGTA
GAAGCAGTAACAATGATGGCTAACATTGCGGTACGTGTTGAAAAATCATTACAATATGAAGATATGTTCAAAAAACGTAT
TAAAGAGTTCACTCCAACAATTACAGATGCAATTAGCCAATCTGTTGCACATACAGCACTTGCTCTTGATGTAGCTGCAA
TCGTAGCTCCAACAGAAAGTGGATATACTGCGAAAATGATCTCTAAATACCGTCCAAAATCTCCAATCGTAGCTGTAACA
TCTGACGAGCAAGTAGGACGTCGTCTTGCACTTGTTTGGGGTGTACAAGCATTTATGGCTGAGAAGCGCGCAGCTTCAAC
TGACGAAATGTTAGATACAGCAATTCAAACAGGTATGGATGCAGGTCTAATCGGACTTGGAGATACTGTAGTGATTACTG
CTGGTGTTCCAGTTGCTGAAACTGGTACAACAAACTTAATGAAAATCCACGTTGTTGGTGAAGAAATTGCTAAAGGACAA
GGAATCGGTCGTAAAGCTGCAAAAGGTAAAGTAGTTGTAGCAAAAACAGCTGCTGAAGCTGTAGCGAACGTAAACGAAGG
TGATATCCTTGTTACAACAAGCACTGATAAAGATATGATTCCTGCAATCGAAAAAGCTGCAGCTTTAGTTGTAGAAGAAG
GTGGCTTAACAAGCCATGCAGCTGTTGTAGGTGTATCAATCGGTATTCCTGTTATCGTTGGTGTAAACGGCGTAACAGCA
ACTTTAAAAAATGGCCAAGAAGTAACAGTTGATGCAGCACGCGGAATTGTTTATAATGGACATGCGGAAGTGCTATAA

Protein sequence :
MRKTKIVCTIGPASESIEKLEQLIEAGMNVARLNFSHGSHEEHGARIKNIREASKKTGKTVGILLDTKGPEIRTHDFVDG
QAELVTGAEVVLSTEQVLGTAEKFSVSYAGLYDDVDPGSRILIDDGLIELEVIEKADGNIRTKVLNSGTVKNKKGVNVPN
VSIKLPGITEKDVKDIIFGIEQKVDFIAASFVRKASDVLEIRELLEEHNAQYIQIVPKIENQEGIDNIDSILEVSDGLMV
ARGDMGVEIPPEEVPLVQKRLIKKCNVLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGQYPV
EAVTMMANIAVRVEKSLQYEDMFKKRIKEFTPTITDAISQSVAHTALALDVAAIVAPTESGYTAKMISKYRPKSPIVAVT
SDEQVGRRLALVWGVQAFMAEKRAASTDEMLDTAIQTGMDAGLIGLGDTVVITAGVPVAETGTTNLMKIHVVGEEIAKGQ
GIGRKAAKGKVVVAKTAAEAVANVNEGDILVTTSTDKDMIPAIEKAAALVVEEGGLTSHAAVVGVSIGIPVIVGVNGVTA
TLKNGQEVTVDAARGIVYNGHAEVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-98 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-98 51
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-98 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-98 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BC4599 NP_834305.1 pyruvate kinase VFG0479 Protein 6e-99 51