Gene Information

Name : hemC (BC4471)
Accession : NP_834183.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4417681 - 4418610 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGCGCAAAATTATTGTAGGGTCACGAAAGAGTAAACTAGCATTAACGCAAACAAACTGGTTTATTGATCAGTTAAAAGC
CCTAGGTCTACCATATGAATTTGAAGTGAAAGAAATTGTCACAAAAGGTGATGTTATTTTAGATGTTACTCTTTCAAAAG
TAGGCGGAAAAGGCTTGTTCGTTAAAGAAATTGAGCATGCGTTACTTACGAAAGAAATCGATATGGCTGTACATAGTATG
AAAGATATGCCAGCCGTACTTCCAGAAGGTTTAATGATTGGCTGTACACCAAAGCGTGTTGACCCTCGTGATGCTTTTAT
CTCAAAAAATGGAGCATCGTTTAAAGAGTTAGCGGAAGGTGCTATTTTAGGTACGAGTAGTTTAAGACGTAGTGCACAGC
TACTCGCTGCGAGACCAGATTTACAAGTGAAGTGGATTCGCGGGAATATCGATACACGTTTACGTAAATTAAAAGAAGAA
GATTACGATGCGATTATTTTAGCGACAGCTGGATTACAAAGAATGGGCTGGGATAATGATGTTATTACAGAACATTTAGA
TGATACGTTATGTGTACCTGCTGTAGGACAAGGTGCATTAGCGATTGAGTGTCGTGAGGATGATAAGGATTTATTGCAGT
TGTTAGCGCATATTAATGATACGATAACAGAAAGAACAGTGGCAGCGGAGCGAGTATTTCTTCATAAACTTGAAGGTGGA
TGCCAAGTTCCAATTGCTGGATATGCAACCCTTACAGAAAACGATGCAATCGAATTAACAGCTCTTGTCGGCTCTATGGA
TGGCTCTGTTTTATTAAAAGAGACAGTAGTGGGTACTAACCCTGAGGAAGTAGGGTTAGAGGCCGCGGACCGTTTAATTA
AACAAGGCGCCAAAGAACTCATTCTTGCTGCAAATAAGGAGCAACAATAA

Protein sequence : 
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSM
KDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEE
DYDAIILATAGLQRMGWDNDVITEHLDDTLCVPAVGQGALAIECREDDKDLLQLLAHINDTITERTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTNPEEVGLEAADRLIKQGAKELILAANKEQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-58 48
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-58 48