Gene Information

Name : BC4366 (BC4366)
Accession : NP_834078.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 4306293 - 4307426 bp
Length : 1134 bp
Strand : -
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAGAGCAAAGACAAAGTTAATTCATGGTATTCGCATAGGAGAACCTTCAACTGGATCTGTAAACGTACCGATTTATCA
AACAAGTACGTACAAACAAGAAGCAGTTGGTAAGCATCAAGGATATGAATATTCACGTACAGGTAACCCAACACGTGCAG
CTTTAGAAGAAATGATTGCTGTATTAGAAAATGGGCATGCTGGATTTGCATTTGGTTCAGGAATGGCTGCTATTACAGCG
ACAATTATGTTGTTCTCAAAAGGTGACCACGTTATTTTAACAGATGATGTGTATGGCGGAACATACCGCGTTATTACGAA
AGTATTAAACCGTTTCGGTATTGAGCATACATTTGTAGATACAACAAACTTAGAGGAAGTTGAAGAAGCGATTCGTCCAA
ATACGAAAGCAATTTATGTAGAAACACCAACGAACCCACTACTAAAAATTACTGATATTAAGAAAATATCTACTCTTGCT
AAAGAGAAAGACTTATTAACAATTATCGATAACACATTCATGACGCCATATTGGCAGTCGCCGATTTCTTTAGGAGCAGA
TATTGTGCTTCATAGTGCAACGAAATATTTAGGAGGTCATAGTGACGTAGTTGCAGGTCTAGTAGTTGTAAATAGCCCAC
AACTAGCAGAAGATCTTCACTTTGTACAAAACTCAACAGGCGGTATTCTTGGACCACAAGATAGCTTCTTACTACTTCGT
GGTTTAAAAACGTTAGGAATTCGTATGGAAGAACATGAAACGAATTCACGCGCTATTGCTGAGTTCTTAAATAATCATCC
AAAAGTAAATAAAGTATATTACCCAGGTCTTGAATCACATCAAAACCACGAATTAGCAACAGAACAAGCAAATGGATTTG
GTGCTATTATCTCATTTGATGTAGATAGTGAAGAGACATTAAATAAAGTACTTGAGAAATTGCAGTACTTTACACTTGCT
GAAAGTTTAGGAGCAGTAGAAAGTTTAATTTCTATTCCATCTCAAATGACACATGCATCAATCCCAGCTGATCGCCGCAA
AGAATTAGGAATTACAGATACATTAATTCGTATTTCTGTCGGTATTGAAGATGGTGAAGATTTAATTGAAGATTTAGCAC
AAGCGTTAGCATAA

Protein sequence :
MRAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKHQGYEYSRTGNPTRAALEEMIAVLENGHAGFAFGSGMAAITA
TIMLFSKGDHVILTDDVYGGTYRVITKVLNRFGIEHTFVDTTNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTLA
KEKDLLTIIDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNSTGGILGPQDSFLLLR
GLKTLGIRMEEHETNSRAIAEFLNNHPKVNKVYYPGLESHQNHELATEQANGFGAIISFDVDSEETLNKVLEKLQYFTLA
ESLGAVESLISIPSQMTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-114 61
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-115 61
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-82 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BC4366 NP_834078.1 cystathionine beta-lyase BAC0207 Protein 3e-65 41