Gene Information

Name : BC4254 (BC4254)
Accession : NP_833968.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 4201028 - 4202191 bp
Length : 1164 bp
Strand : +
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAGCTATTCTATAGATACACTCTTACTACACAACCAATATAAACACGACTCGCAAACAGGCGCTGTGAACGTTCCTAT
TTATAATACATCAACTTTTCACCAGTTTGATGTAGATACGTTCGGAAAATATGACTATAGCAGGTCAGGAAATCCAACTC
GTGAAGCTCTTGAAGATATCATTGCTTTATTAGAAGGCGGAACAAAAGGATTCGCCTTTGCATCAGGCATTGCAGCGATT
TCCACTGCATTCCTCCTTCTTTCACAAGGTGATCACGTACTCATTTCAGAAGATGTGTACGGAGGCACTTACCGAGTGAT
AACTGAGGTACTCTCCCGTTACGGTGTTTCACATACATTTGTTGATATGACCAATTTAGAAGAAATAAAACAAAACATTA
AACCAAATACAAAGCTCTTTTATGTAGAAACACCTTCTAACCCACTTTTAAAAGTGACAGATATTCGCGAGGTTTCTAAA
CTCGCAAAATCTATTGGCGCTCTTACTTTTGTTGATAATACATTTTTGACACCACTATTCCAAAAACCACTTGAACTTGG
AGCTGATGTCGTTCTTCATAGTGCTACAAAATTTATTGCTGGTCATAGTGATGTTACTGCCGGATTAGCAGTAGTAAAAG
ATTCAGAACTCGCTCAAAAGCTTGGATTTTTACAAAATGCATTCGGTGCTATTTTAGGACCTCAAGATTGTTCTCTCGTA
CTTCGCGGTCTAAAAACATTGCATGTACGCCTCGAACATTCAGCTAAAAATGCCAATAAAATCGCACATTATTTACAAGA
GCACTCTAAAGTAAAAAATGTCTATTATCCGGGATTACAAACTCATCTCGGATTTGATATTCAACAATCTCAAGCAACAT
CAGCTGGAGCGGTCTTATCGTTTACTTTGCAGTCAGAAGATGCACTCCGCAAATTTTTATCAAAAGTAAAATTACCTGTT
TTTGCAGTTAGTTTAGGAGCTGTAGAGTCAATTCTTTCTTATCCAGCAAAAATGTCACATGCAGCACTGTCGCAAGAAGC
TCGTGATAAAAGAGGAATCTCTAATTCATTACTTCGGTTATCAGTCGGTCTTGAAAATGTTAACGATTTAATATCCGATT
TTGAAAATGCCCTTTCTTATGTAGAAGAACCTGTAAATGCATAG

Protein sequence :
MSYSIDTLLLHNQYKHDSQTGAVNVPIYNTSTFHQFDVDTFGKYDYSRSGNPTREALEDIIALLEGGTKGFAFASGIAAI
STAFLLLSQGDHVLISEDVYGGTYRVITEVLSRYGVSHTFVDMTNLEEIKQNIKPNTKLFYVETPSNPLLKVTDIREVSK
LAKSIGALTFVDNTFLTPLFQKPLELGADVVLHSATKFIAGHSDVTAGLAVVKDSELAQKLGFLQNAFGAILGPQDCSLV
LRGLKTLHVRLEHSAKNANKIAHYLQEHSKVKNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSEDALRKFLSKVKLPV
FAVSLGAVESILSYPAKMSHAALSQEARDKRGISNSLLRLSVGLENVNDLISDFENALSYVEEPVNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-89 52
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-88 47
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-87 47