Gene Information

Name : BC4253 (BC4253)
Accession : NP_833967.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4199919 - 4201031 bp
Length : 1113 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGTCAACAATCGAAACAAAACTAGCACAAATCGGAAATCGCAGTGAAACTACAACTGGAACGGTTAATCCACCAGTTTA
TTTCTCAACCGCTTATCGTCACGAAGGAATTGGTAAATCTACTGGCTTTGACTATTCACGAACTGGCAATCCAACTCGCG
GTCTTTTAGAACAGGCGATTGCAGACTTAGAATATGGCGAACAAGGTTATGCCTGTAGTTCAGGGATGGCGGCTGTTCTC
CTCGTCCTTTCTCTATTCCGCTCTGGAGACGAACTTATTGTATCTGAAGATTTATACGGGGGAACGTATCGATTATTTTC
TGAGCATGAAAAAAAGTGGAATGTTCGATGTAGATACGTAAATACACAGTCTATTAAACAAATTGAGCAAGCTATCACAA
CTGAAACGAAGGCTATTTTCATAGAAACTCCAACTAATCCATTAATGCAAGTTACTGATATTGCTGCTGTCGCAACTGTA
GCGAAAAGGAACGGACTACTTCTTATTGTAGACAACACTTTCTACACACCTTATATACAGCAACCATTAACAGAAGGTGC
TGACATTGTACTTCATAGCGCAACGAAATATTTAGGGGGACATAACGATGTACTAAGCGGGCTTGTAGTTGCAAAAGGAA
AGGAACTTTGCGAGGAAATCGCTCATTATCATAATGCATCAGGTGCAGTTTTAAGCCCATTTGACTCATGGTTATTAATT
CGCGGTATGAAAACGTTAGCGCTTCGCATGAGGCAACATGAAGAAAATGCGAAAGCAGTTGTTGCGTATTTAAATGATGA
GGACGGGGTGACAGATGTATTTTATCCAGGAAGAGGTGGCATGATCTCATTCCGCCTTAAAGATGAAGCTTGGATTAATC
CATTCTTACAATCTTTATCCTTAATTACATTTGCCGAAAGTCTTGGTGGTGTAGAAAGTTTAATGACTTATCCAGCAACG
CAAACACATGCTGATATTCCTGAAGAAATTAGAACAGCAAACGGCGTATGCAATCGTCTTCTTCGATTCTCAGTTGGCAT
TGAAAATAGTAACGATTTAATTCAAGACTTAAAGCAAGCCATTAAACTCGTAAAAGAAGGTGTAAGAATATGA

Protein sequence :
MSTIETKLAQIGNRSETTTGTVNPPVYFSTAYRHEGIGKSTGFDYSRTGNPTRGLLEQAIADLEYGEQGYACSSGMAAVL
LVLSLFRSGDELIVSEDLYGGTYRLFSEHEKKWNVRCRYVNTQSIKQIEQAITTETKAIFIETPTNPLMQVTDIAAVATV
AKRNGLLLIVDNTFYTPYIQQPLTEGADIVLHSATKYLGGHNDVLSGLVVAKGKELCEEIAHYHNASGAVLSPFDSWLLI
RGMKTLALRMRQHEENAKAVVAYLNDEDGVTDVFYPGRGGMISFRLKDEAWINPFLQSLSLITFAESLGGVESLMTYPAT
QTHADIPEEIRTANGVCNRLLRFSVGIENSNDLIQDLKQAIKLVKEGVRI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-72 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-73 45