Gene Information

Name : guaA (BC0296)
Accession : NP_830147.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 259858 - 261405 bp
Length : 1548 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGATTATTTTGAAGAAACAACACGATACAATTATCGTTTTAGATTTTGGAAGTCAATACAATCAGTTAATAGCACGTCG
AATTCGTGAGTTCGGTGTATACAGTGAACTTCATCCACATACAATTACTGCAGAAGAAATTAAAGCAATGAACCCAAAAG
GGATTATTTTCTCTGGTGGACCAAATAGTGTATACGGTGAAGGTGCATTACATTGTGATGAAAAAATCTTTGAACTAGGT
TTACCAATCTTCGGTATTTGTTACGGTATGCAGCTTATGACGCAACAATTCGGTGGTAAAGTAGAGCGTGCAAATCACCG
TGAGTACGGAAAAGCTGTTCTTAAAGTAGAGAACGAATCAAAATTATATGCGAACCTTCCAGAAGAGCAAGTTGTATGGA
TGAGCCATGGCGACTTAGTAACTGGTTTACCTGAAGGATTCGTAGTAGATGCAACAAGTGAGTCTTGCCCAATTGCTGGT
ATGAGCAATGAAGCGAAAAACTTATACGGTGTACAATTCCACCCAGAAGTACGTCACTCTGAGCACGGTAACGATTTAAT
TAAAAACTTCGTATTCGGTGTATGTGGTTGTTCTGAAGGATGGAACATGGAGAACTTTATTGAAGTAGAATTAGAAAAGA
TTCGTGAAACTGTTGGAGACAAAAAAGTACTATGCGCACTTAGTGGCGGTGTAGACTCTTCTGTTGTAGCAGTATTAATT
CATAAAGCAATTGGTGATCAATTAACATGTATTTTCGTTGACCACGGTTTACTTCGTAAAGGTGAAGCAGAAGGCGTTAT
GAAAACATTTAGCGAAGGCTTCCATATGAACGTTATTAAAGTGGATGCAAGAGACCGCTTCATGGACAAGTTAAAAGGTG
TAGAAGATCCAGAACAAAAACGTAAAATCATCGGTAACGAATTCATTTACGTATTTGATGATGAAGCGTCAAAATTACAA
GGTATGGACTTCTTAGCGCAAGGTACACTTTACACAGATATCGTTGAGAGTGGTACAGCAACTGCGCAAACAATTAAATC
TCACCATAACGTTGGTGGACTTCCAGAAGACATGCAGTTCAAATTAATTGAGCCTTTAAACACGTTATTTAAAGACGAAG
TACGTGTATTAGGATCTGAATTAGGAATTCCTGATGAAATCGTATGGCGTCAACCATTCCCAGGACCGGGTCTTGGTATT
CGTGTATTAGGTGAAATCACAGAAGAGAAATTAGAAATCGTTCGTGAATCTGATGCGATTTTACGTGAAGAAATTATTAA
AGCGGGCTTAGACCGTGAAATCTGGCAATACTTCACTGCGCTTCCTGGTATGCGTAGCGTAGGTGTTATGGGTGACGAGC
GTACTTACGATTACACAGTAGGTATCCGTGCGGTAACATCTATCGACGGTATGACAGCTGACTGGGCACGTATCCCTTGG
GACGTATTAGAGAAAATCTCTGTACGTATCGTAAACGAAGTAAAACACGTTAACCGTATCGTGTATGATGTAACGAGTAA
GCCACCAGCAACTATTGAGTGGGAATAG

Protein sequence :
MIILKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFELG
LPIFGICYGMQLMTQQFGGKVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAG
MSNEAKNLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLI
HKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKVDARDRFMDKLKGVEDPEQKRKIIGNEFIYVFDDEASKLQ
GMDFLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGI
RVLGEITEEKLEIVRESDAILREEIIKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPW
DVLEKISVRIVNEVKHVNRIVYDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-139 54