Gene Information

Name : BC2304 (BC2304)
Accession : NP_832067.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 2248764 - 2250380 bp
Length : 1617 bp
Strand : +
Note : -

DNA sequence : 
ATGCTAGTAGGTTATACAGAATGGCCAAAAGAATTTGCCGATCATTATCGAGAAGAAGGATGTTGGCTTGGTGAAACATT
TGGAGGAGTGTTAAGAGAGCGGGCTGAGAAATATGGAGATCGAATCGCGGTTGTAAGTGGTAAGAAGCATATGACATATA
GTGAACTTGATAAAAATGCCGATCGTTTAGCAGCAGGTTTACTGAATTTAGGAATAAAGAAAGGGGACAGAGTTGTAATC
CAGTTACCTAACATTATCGAGTTTTTCGAAATATGTTTTGCACTATTTCGAATTGGAGCGCTTCCTGTCTTTGCACTACC
TTCACATCGAAGCAGTGAAATTAGTTATTTTTGTGAGTTTGGTGAGGCGAGCGCTTACGTTATTTCAGATAAGGCTCTCG
GTTTTGATTATCGAAAACTAGCAAGAGAAGTGAAAGAGAAAGTGCCAACTTTACAACGTGTAATTGTAGTGGGGGAAGAA
GAAGAGTTTGTGAACATAAATGATCTGTATATGGATCCCGTCTCATTACCAGAAGTTCAGCCAAGTGATGTTGCATTTCT
CCAATTATCAGGAGGGACAACAGGTCTTTCTAAATTAATTCCTAGAACACATGATGACTATATTTATAGTTTACGTGTAA
GCGCTGAAATTTGTAATTTGAATGCAGAAAGCGTCTATATGGCAGTTCTTCCAGTAGCACACAATTACCCAATGAGTTCT
CCAGGGACATTTGGAACTTTCTATGCGGGTGGAAAAGTGGTATTGGCAACTGGTGGTAGTCCAGATGAGGCATTTGCTCT
TATTGAAAAAGAAAAAGTTACAATTACAGCGCTCGTTCCCCCATTAGCAATGATTTGGCTTGATGCTGCATCTTCTCGTA
ATACCGATTTATCGAGCCTAGAGGTTATTCAAGTAGGTGGTGCTAAGTTTAGCGCTGAGGTTGCAAGACGTATACGCCCT
ACATTTGGATGTACGTTACAGCAAGTATTCGGTATGGCGGAAGGATTAGTGAACTATACAAGATTAGACGATCCGGAAGA
AATTATTATTCATACACAAGGTAGACCAATGTCTGCACTCGATGAAGTACGAGTTGTTGATGAAAATGACAACGATGTAC
AACCTGGCGAAGTAGGTAGTTTATTAACAAGAGGTCCATATACAATTCGTGGTTACTATAAAGCTGAAGAGCATAATGCA
CGATCATTTACAAAGGATGGGTTTTATCGCACAGGTGATCTTGTAAAAGTAAATGAACAAGGATACATCATTGTAGAAGG
AAGAGATAAAGATCAAATTAACCGTGGTGGTGAGAAAGTTGCTGCGGAAGAAGTTGAAAATCATTTATTAGCACACGATG
CGGTTCATGACGTAGCAATTGTATCTATGCCTGACGATTATTTAGGTGAACGCACCTGTGCTTTTGTTATAGCTCGCGAA
CAAGTTCCGGCAGTAAGTGAATTAAAAATGTTTTTAAGAGAACGTGGTATCGCGGCTTATAAAATTCCAGATCGAATTGA
ATTTATTGAATCATTCCCGCAAACAGGAGTCGGAAAAGTCAGCAAAAAAGAACTACGTAAAGTCATTGCTGAAAAACTAA
TTATAGTAAAACAATAA

Protein sequence : 
MLVGYTEWPKEFADHYREEGCWLGETFGGVLRERAEKYGDRIAVVSGKKHMTYSELDKNADRLAAGLLNLGIKKGDRVVI
QLPNIIEFFEICFALFRIGALPVFALPSHRSSEISYFCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQRVIVVGEE
EEFVNINDLYMDPVSLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLNAESVYMAVLPVAHNYPMSS
PGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSRNTDLSSLEVIQVGGAKFSAEVARRIRP
TFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQGRPMSALDEVRVVDENDNDVQPGEVGSLLTRGPYTIRGYYKAEEHNA
RSFTKDGFYRTGDLVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTCAFVIARE
QVPAVSELKMFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKELRKVIAEKLIIVKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-120 51
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-120 51
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 4e-120 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-120 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-120 50
ybtE CAA21394.1 - Virulence HPI Protein 4e-120 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 3e-120 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 6e-120 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-120 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BC2304 NP_832067.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-137 53
BC2304 NP_832067.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 7e-114 48
BC2304 NP_832067.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 4e-111 45