Gene Information

Name : thyA (BC2191)
Accession : NP_831956.1
Strain : Bacillus cereus ATCC 14579
Genome accession: NC_004722
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2137845 - 2138801 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACATGCTGAAAATGAATACTTAAATTTATGCCGCCATGTAATGGAACATGGTACGAAGAAAGAAGACCGTACAGG
GACAGGCACTGTATCTGTATTTGGATATCAAATGCGTTTTGATCTAAGTAAAGGTTTTCCTTTATTAACAACAAAGAGAG
TACCGTTTCGCCTTGTAGCAAGTGAACTGCTTTGGTTTATGAAAGGTGATACAAATATTCGCTATTTATTGCAGCATAAT
AATAACATTTGGAATGAATGGGCTTTTAAGAGCTGGGTAGAAAGTGATGAGTATACTGGCCCTGACATGACTGATTTTGG
TCTTCGCTCACAACAAGATGAAGAATTTAAAGTACAGTACGACGAGCAAATGGAATTGTTTAAAAAGAACGTTTTAGAAG
ATGATGAGTTCTCAAATAAATATGGTTATTTAGGAGACGTTTACGGTAAACAGTGGCGTGCTTGGAAAACGACAGCTGGT
GAGACACTTGATCAATTAAAAGATGTAATTGAAATGATTAAAAAAACACCAGACTCACGTCGTTTAATCGTTTCTGCCTG
GAATCCAGAAGATGTACCAAGTATGGCCTTACCGCCTTGTCATACGCTATTCCAGTTTTATGTAGCAGATGGAAAGCTTT
CTTGTCAGTTATATCAAAGAAGTGGTGACATATTCCTTGGGATTCCATTTAACATTGCAAGTTACTCACTACTAACACAT
TTAATTGCACATGAATGCGGACTTGAAGTGGGAGAATTTGTTCATACAATTGGTGATGCACACATTTATACAAATCATTT
TGAACAAGTAGAAAAGCAATTGGCACGTGAACCACGTCCATTCCCGAAACTTACATTAAATCCAGATGTGAAATCTGTTT
TCGATTTTGAAATGGAAGATTTAACGATTGAAGGATACGATCCGCATCCAGCAATTAAAGCACCGGTTGCAGTATAA

Protein sequence :
MKHAENEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHN
NNIWNEWAFKSWVESDEYTGPDMTDFGLRSQQDEEFKVQYDEQMELFKKNVLEDDEFSNKYGYLGDVYGKQWRAWKTTAG
ETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTH
LIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 6e-106 65