Name : serS-1 (EF0100) Accession : NP_813903.1 Strain : Enterococcus faecalis V583 Genome accession: NC_004668 Putative virulence/resistance : Unknown Product : seryl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0172 EC number : 6.1.1.11 Position : 103833 - 105104 bp Length : 1272 bp Strand : + Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGCTGGATATGAAAAAAATTCGCCAAAATGTAGAAGTGGTACAGAAAAAGTTAAAAACACGTGGTGTGGACGAGGAAGT TTTATTACGCTTTTTGGCTTTAGATGAAGGACGGAGAGCGTTACTTGTTAAAGTTGAAGAACTGAAAAAACACCGTAATC AGGTGTCAGGAGAAATTGCACAATTAAAGCGTGCACAAAAAGATGCTTCACAACAATTGCTAAATATGCAAGAAGTTAGC GAGCAAATTAAAGTTTTAGATCAAGAAGTTGTTCATTTGCAAGAACAATGCACAGCCATTGCAGAACGTTTGCCTAACTT ACCTCATGAGAGCGTACCTGTTGGCGCAGACGAAGCCGCCAACGTAGAAGTTCGGCGGTGGAGTACGCCGAAAACTTTTT CATTTGAACCAAAACCACATTGGGAAATCGGTGAAGCCTTAGGAATTTTAGATTTTGAAAGAGGCGCGAAAGTATCTGGT AGCCGTTTTCTTTATTACAAAGGCTTAGGGGCTCGTTTAGAACGAGCGGTCTATAATTTTATGTTAGATCAACATGTTAA TGAACATGGTTATACCGAAGTGATTCCTCCTTATTTGGTCAATAGCAAAGCAATGTTTGGCACCGGTCAGTTTCCTAAGT TCAAAGAAGATGTTTTCCAAGTTGCAGAAAGTGATTTGACGCTGATCCCCACAGCGGAAGTCCCGTTAACTAACTACTAT AATAATGAAATTTTAGATGCGCAAGAGTTACCGATTTATTTTACTGCTTTAAGTCCTTCTTTTCGCTCGGAAGCGGGTAG TGCAGGTCGTGATACCCGAGGATTAATTCGTTTACACCAGTTTCATAAAGTAGAAATGGTTAAATTTAGTGATGCAGAAC ACTCCTATGAAGAATTAGAAAAAATGACCAACAATGCTGGAGACATTTTAGAAAAATTGGGCCTCCCTTATCGAGTGATT ACTCTTTCGACAGGTGACATGGGCTTCTCGGCAGCGAAAACCTATGATTTAGAAGTTTGGATTCCGGCACAGAAAACGTA TCGAGAAATTAGTTCTTGTTCAAACTGTGAAGACTTCCAAGCACGTCGGGCGTTGATTCGTTATCGTGATAAAACGGGTC ATGTTCAATATGCCCATACTCTTAATGGGTCAGGACTTGCTGTTGGTCGAACAGTGGCTGCCATTTTGGAAAATTATCAA AATGAAGATGGCACCGTAACGATTCCAGAAGTTCTACGTCCTTATATGGGCGGTTTAACGAAAATAGATTAA Protein sequence : MLDMKKIRQNVEVVQKKLKTRGVDEEVLLRFLALDEGRRALLVKVEELKKHRNQVSGEIAQLKRAQKDASQQLLNMQEVS EQIKVLDQEVVHLQEQCTAIAERLPNLPHESVPVGADEAANVEVRRWSTPKTFSFEPKPHWEIGEALGILDFERGAKVSG SRFLYYKGLGARLERAVYNFMLDQHVNEHGYTEVIPPYLVNSKAMFGTGQFPKFKEDVFQVAESDLTLIPTAEVPLTNYY NNEILDAQELPIYFTALSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFSDAEHSYEELEKMTNNAGDILEKLGLPYRVI TLSTGDMGFSAAKTYDLEVWIPAQKTYREISSCSNCEDFQARRALIRYRDKTGHVQYAHTLNGSGLAVGRTVAAILENYQ NEDGTVTIPEVLRPYMGGLTKID |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
serS | YP_003446791.1 | seryl-tRNA synthetase | Not tested | The aminoglycoside resistance gene cluster | Protein | 9e-149 | 70 |