Gene Information

Name : leuS (EF0801)
Accession : NP_814544.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 761593 - 764007 bp
Length : 2415 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCTACAATCACAAAGAGATTGAGAAAAAATGGCAAAAATATTGGGCTAAGAACAATTGTTTCAATACATTGGACGA
CCCAAATAAAGAAAAATTTTATGCACTAGATATGTTTCCCTATCCATCTGGACAAGGCTTACACGTAGGTCACCCGGAAG
GCTATACAGCAACCGATATTCTTTCACGTATGAAACGTGCGCAAGGCTATAATGTGTTGCATCCAATGGGCTGGGATGCG
TTTGGTTTGCCAGCAGAGCAATATGCGTTAGATACAGGAAATGACCCAGCTGAATTTACTAAGAAAAATATCGAAACATT
CCGTCGCCAAATTAATTCACTAGGATTCAGCTATGATTGGAATCGTGAAATTAATACCACTGATCCTGAATATTACAAAT
GGACACAATGGATATTTACAAAATTATATGAAAAAGGGTTAGCTTATGAAGCAGAAGTTGCGGTTAACTGGGTCCCTGAA
TTAGGAACTGTTATTTCAAATGAAGAAGTCATTGATGGAAAAAGTGAACGTGGCGGTTATGATGTGGTTCGCCGACCAAT
GCGTCAATGGATGCTGAAAATTACTGCTTATGCAGATCGCTTATTAGAAGATTTAGAGCTTGTTGATTGGCCAGAGAGTA
TTAAAGATATGCAACGAAATTGGATTGGACGTTCTGAAGGAGCCAATGTGACCTTTAAAGTCGCTGGCACAGAAGAAAGT
TTCACGGTGTTTACAACCCGTCCTGATACCTTGTTTGGTGCAACCTATACTGTTCTAGCTCCTGAACTAGAACTAGTGAA
AAAAATTACGACACCTGAACAAACAGCAGCTGTAGAAGCATATATTGAAGAAACCTCAAAAAAATCTGATTTAAATAGAA
CGGATTTAGCAAAAGAAAAAACAGGTGTTTTCACAGGTGCGTATGCTATAAATCCAGTCAATGGCCAAGAAATTCCAATT
TGGATTGGCGATTATGTTTTAGCAAGCTATGGCACAGGCGCAATCATGGCGGTCCCAGCACATGATGAACGGGATTACGA
ATTTGCGAAAACATTTGGCATTGATATCCTACCAGTAATCGCAGGTGGCGACATTACAACAGAAGCCTATACAGGGGATG
GACCGCATATCAATTCTGATTTCTTAAATGGATTAAACAAAGCAGAAGCCATCGCTAAAATGAATGAGTGGCTAGAAGAA
AATCACGTAGGGAAAAAAGAAGTATCTTATCGTTTACGTGACTGGTTATTCTCTCGTCAACGCTACTGGGGTGAACCAAT
TCCTGTGATCCATTGGGAAGATGGAACAACCACAACGGTTCCTGAATCTGAGTTACCTCTACGTTTACCAGTAACATCGG
ATATTCGCCCAAGTGGAACTGGGGAATCGCCATTAGCAAACATTGATGAATGGGTCAATGTCGTCGACCCTGAAACTGGC
ATGAAGGGAAAACGTGAAACGAATACTATGCCACAATGGGCTGGAAGCTCTTGGTATTACTTACGATTCATTGATCCTCA
TAATAAAAATGAAATTGCTGATTTTGAAAAATTAAAACGTTGGTTACCAGTTGATATCTATATTGGTGGTGCCGAACATG
CGGTGCTGCATTTACTTTATGCTCGTTTTTGGCATAAATTCTTATATGATATTGGTGTGGTTCCTACCAAAGAACCTTTC
CAAAAATTATACAACCAAGGTATGATTTTAGGAGAAAACAACGAAAAAATGTCTAAATCACGTGGCAATGTTGTAAATCC
CGATGATGTGGTGGCTAAATATGGTGCGGATACGTTACGTCTTTATGAAATGTTCATGGGCCCATTAGATGCTTCCATTG
CTTGGAATGAAAATGGATTAGAAGGAAGTCGTAAATTCTTAGATCGCGTTTGGCGTCTGATTGTTGATGAAGAAGGCAAA
ATGCGTGACCGAATTACCACAATTAATGATGGCCGTTTAACGAAAGTTTATCATCAAACGGTTAAAAAAGTGACAGAAGA
TATGGCAAACTTGCACTTTAATACAGCGATTTCTCAATTAATGGTTTTTGTGAATGAAGCCAATAAAGTGGATGCCTTAC
CTTATGAATATGTGGAAGGATTTGTCCAATTACTTGCGCCAATCGCGCCACATATTGGTGAAGAACTATGGCAAATTTTA
GGTAACGAGGAAAGTTTAACTTATGTCCCTTGGCCAACCTATGATGAAACGGCCTTAGTAGAAGATGAAGTGGAAGTAGT
TTTCCAAGTGAACGGAAAATTACGTGGCAAACAAAATGTCGCTCGTGGGTTAAGCAAAGAAGAATTAGAACAAATTGCAA
TGAACCATGAAGCTGTTAAAGAATTTATTGAAGGAAAAACAGTGCGCAAAGTGATTGCTGTTCCAGATAAATTAGTAAAT
ATTGTTGCAAATTAA

Protein sequence :
MSYNHKEIEKKWQKYWAKNNCFNTLDDPNKEKFYALDMFPYPSGQGLHVGHPEGYTATDILSRMKRAQGYNVLHPMGWDA
FGLPAEQYALDTGNDPAEFTKKNIETFRRQINSLGFSYDWNREINTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
LGTVISNEEVIDGKSERGGYDVVRRPMRQWMLKITAYADRLLEDLELVDWPESIKDMQRNWIGRSEGANVTFKVAGTEES
FTVFTTRPDTLFGATYTVLAPELELVKKITTPEQTAAVEAYIEETSKKSDLNRTDLAKEKTGVFTGAYAINPVNGQEIPI
WIGDYVLASYGTGAIMAVPAHDERDYEFAKTFGIDILPVIAGGDITTEAYTGDGPHINSDFLNGLNKAEAIAKMNEWLEE
NHVGKKEVSYRLRDWLFSRQRYWGEPIPVIHWEDGTTTTVPESELPLRLPVTSDIRPSGTGESPLANIDEWVNVVDPETG
MKGKRETNTMPQWAGSSWYYLRFIDPHNKNEIADFEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPF
QKLYNQGMILGENNEKMSKSRGNVVNPDDVVAKYGADTLRLYEMFMGPLDASIAWNENGLEGSRKFLDRVWRLIVDEEGK
MRDRITTINDGRLTKVYHQTVKKVTEDMANLHFNTAISQLMVFVNEANKVDALPYEYVEGFVQLLAPIAPHIGEELWQIL
GNEESLTYVPWPTYDETALVEDEVEVVFQVNGKLRGKQNVARGLSKEELEQIAMNHEAVKEFIEGKTVRKVIAVPDKLVN
IVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 71