Gene Information

Name : clpE (EF0706)
Accession : NP_814457.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding protein ClpE
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 659709 - 661961 bp
Length : 2253 bp
Strand : -
Note : similar to GP:4103470, and GP:4103470; identified by sequence similarity

DNA sequence :
GTGTTTCATTCAATGATTTGTCAAAATTGTCAACAAAATGAAGCAACAATTCATTTATATGCAAATGTGAATGGTCAAAG
AAAACAACTGGACTATTGCCAAAGCTGCTATCAAAAATTAAAAAATCAAGCAAATAATTCCCCTCAAAATATGGGACAAG
ACCCTTTTGGCTTTGGGAGTTTAGACGATTTATATCGTTCTCTTTCTCGCCAAATGCAACAAGGTAATCCTTATGAACAA
CAAACACCACCCACTCAATTTGGTGATGGTGGTAATGGAGGTCAACCCCCTCGCGGAGGCGCTGGCGCTGGTCAAGGTTT
ACTAGGCGAGTATGGGATTAACATCACCGAAGCGGCACGCCAAGGAGATATCGATCCTGTGGTAGGACGTGACCAAGAAA
TTAAGCGTGTCATTGAAATCTTAAATCGCCGTACAAAAAACAACCCCGTTTTAATCGGTGAACCAGGTGTTGGTAAAACA
GCCGTTGTCGAAGGTTTAGCCCAAAAAATTGTCGATGGCGATGTGCCCCAAAAATTATTGGACAAAGAAGTCATTCGTTT
AGATGTGGTTTCACTTGTTCAAGGAACTGGTATTCGCGGACAATTTGAAGAACGGATGCAAAAATTGATTGAAGAAATCA
CTGAAGCTGAAAATGTCATTTTATTTATTGATGAAGTCCATGAAATTGTGGGTGCTGGTGCTGCTGGTGATGGCAATATG
GATGCTGGCAATATTTTAAAACCAGCCTTAGCACGTGGTGAATTACAATTAGTCGGTGCCACAACTTTAAATGAGTACCG
TATTATTGAAAAAGATGCTGCCTTAGAACGTCGGATGCAACCAGTCCAAGTAGATGAGCCAACCGTTGCCGAAACCATAA
CGATTTTACATGGTTTGCAAAAACGTTATGAAGATTATCATCATGTTAAATATACAGATGAAGCGATTAACGCAGCAGCA
AACTTATCCAATCGTTACATTCAAGATCGCTTTTTACCAGATAAAGCGATTGACTTGTTAGATGAATCTGGTTCAAAAAT
GAATCTAACTATCCAACTCGTCGATCCAAAAACAATTGATAAAAAATTAGCAGAAGCGGAACAACAAAAACAACAAGCTT
CCGCAGAAGAAGATTTTGAAAAAGCGGCTTATTATCGTGATCAAATCAATAAATTACAAGCAATGAAAGAAAAACAAATC
AGCGATGAAGAAACACCAGTCATCACTGAAAAAGATATTGAAGCCATTGTGGAACAAAAAACTGGCATTCCTGTCGGTGA
CTTAAAAGAAAAAGAACAAACCCAATTGAAAAATTTAGCTGTTGACTTAAAAGCTCATGTTGTCGGACAAGATGATGCCG
TCGATAAAGTAGCTAAAGCGATTCGTCGCAATCGTGTAGGCCTAGGCAAACAAAACCGCCCAATTGGTTCCTTCTTATTT
GTTGGGCCAACAGGCGTTGGTAAAACAGAATTAGCAAAACAATTAGCTTTTGAGCTATTCGGTTCAGAAGATTCGATGGT
TCGTTTTGATATGAGTGAGTATATGGAAAAACACAGTGTTTCTAAACTGATTGGTTCTCCTCCAGGCTATGTTGGTTATG
ACGAAGCTGGACAACTCACAGAAAAAGTCCGTCGTAATCCTTATAGTTTAATTTTATTGGATGAAATTGAAAAAGCGCAT
CCTGATGTTTTACACATGTTTTTACAAATTCTCGACGATGGTCGTTTAACAGATGCACAAGGTCGTACAGTCAGCTTTAA
AGACACCATCATTATCATGACAAGTAATGCTGGAACAGGAGCTGTGGAAGCCAACGTTGGCTTCGGTGCTGCCCGTGAAG
GTGTGACTAAATCTGTTTTAGGTCAATTGAACAACTTCTTCACCCCCGAATTCCTTAACCGTTTCGATGGTATTATCGAA
TTCAAAGCATTAAGCAAAGAAAACCTGATGAACATTGTCAGCTTGATGTTAGAAGAAGTAAATGGCTTATTAGCTAAACA
AAAATTACACATTGAGGTTCCAACAGAAGTCAAAGAGAAACTCGTTGATTTAGGTTATGATCCTGCAATGGGCGCTCGTC
CTTTACGTCGAACAATTCAAGAACAAATTGAAGACGGCATTGCTGAATACTATCTAGATCATCCTGAAAATCATCAATTA
GTCGCAGCGTTAGATAACGAAGGTAAAATTATCGTAACTGGCGCACAAGAAGTGACTAAAACAGAAACTTCAACATCTGA
CCAAGCAGAATAA

Protein sequence :
MFHSMICQNCQQNEATIHLYANVNGQRKQLDYCQSCYQKLKNQANNSPQNMGQDPFGFGSLDDLYRSLSRQMQQGNPYEQ
QTPPTQFGDGGNGGQPPRGGAGAGQGLLGEYGINITEAARQGDIDPVVGRDQEIKRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLLDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEITEAENVILFIDEVHEIVGAGAAGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVQVDEPTVAETITILHGLQKRYEDYHHVKYTDEAINAAA
NLSNRYIQDRFLPDKAIDLLDESGSKMNLTIQLVDPKTIDKKLAEAEQQKQQASAEEDFEKAAYYRDQINKLQAMKEKQI
SDEETPVITEKDIEAIVEQKTGIPVGDLKEKEQTQLKNLAVDLKAHVVGQDDAVDKVAKAIRRNRVGLGKQNRPIGSFLF
VGPTGVGKTELAKQLAFELFGSEDSMVRFDMSEYMEKHSVSKLIGSPPGYVGYDEAGQLTEKVRRNPYSLILLDEIEKAH
PDVLHMFLQILDDGRLTDAQGRTVSFKDTIIIMTSNAGTGAVEANVGFGAAREGVTKSVLGQLNNFFTPEFLNRFDGIIE
FKALSKENLMNIVSLMLEEVNGLLAKQKLHIEVPTEVKEKLVDLGYDPAMGARPLRRTIQEQIEDGIAEYYLDHPENHQL
VAALDNEGKIIVTGAQEVTKTETSTSDQAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-144 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE NP_814457.1 ATP-dependent Clp protease, ATP-binding protein ClpE VFG0080 Protein 0.0 61
clpE NP_814457.1 ATP-dependent Clp protease, ATP-binding protein ClpE VFG0079 Protein 5e-149 53