Gene Information

Name : EF0517 (EF0517)
Accession : NP_814296.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 478430 - 479368 bp
Length : 939 bp
Strand : -
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATTGCAATTGCAGGGGCCGGCGCGATGGGTTCCCGGTTCGGACTGATGTTGAAACAAGGTGGTAACGATGTTTT
GCTAATCGACGGCTGGCAGGAGCATATCAATGCCATCAAAGAAAACGGATTGAAGGCTAATTATAATGGCGAAGAAATTA
CTGTTAAAGTCTCAATTGTTAATCAGAATGAGGTGCCCACTGGTGAGCAATTTGATTTGATTATCTTATTCACGAAGGCA
ATGCAGTTGGAAAAAATGCTGCAGGATGTTAAACCATTAATTGCTGATCACACAGAAGTTTTGTGTCTTTTAAACGGTAT
CGGTCATGAAGACGTAATCGAAAAATTCGTACCGATGGAAAAAATCTTTATCGGCAACACCATGTGGACTGCTGGTCTAG
AAGGTCCCGGCAAGGCTAAATTATTTGGCAGCGGGTCTGTTGAATTGCAAAATCTAGGTATTGGCCAAGAAGAATCAGCG
AAAAAATTGGCGGAAACTTTGTCCGCGTCTGGTTTAAATGCCAAATATTCCGACAACATTCATTATTCAATTTATCGTAA
AGCTTGTGTCAATGGTACGATGAATGGCTTATGCACGATTTTAGACGTCAATATGGCGGGGCTTGGTGCAACCAAACCTG
CTCATGACATGGTAGTGACTATTGTTAACGAATTTGCAGCTGTTGCTGCCAAAGAAAACGTCAACTTAGACATTCCCGAA
GTAATCGAACATGTAGAAACTTGTTTTGACCCGACTACGATTGGTATGCATTTCCCATCGATGCACCAAGACTTGATAAA
AAATAACCGTTTGACCGAGATTGACTACATCAACGGAGCCATTTCTCGTAAAGGTAAAAAATATGGAGTAGTAACTCCTT
ACTGTGATTTCTTAACGCAACTGGTTCATAGTAAAGAAGAAATTCTAGGAGCGAAATAG

Protein sequence :
MKIAIAGAGAMGSRFGLMLKQGGNDVLLIDGWQEHINAIKENGLKANYNGEEITVKVSIVNQNEVPTGEQFDLIILFTKA
MQLEKMLQDVKPLIADHTEVLCLLNGIGHEDVIEKFVPMEKIFIGNTMWTAGLEGPGKAKLFGSGSVELQNLGIGQEESA
KKLAETLSASGLNAKYSDNIHYSIYRKACVNGTMNGLCTILDVNMAGLGATKPAHDMVVTIVNEFAAVAAKENVNLDIPE
VIEHVETCFDPTTIGMHFPSMHQDLIKNNRLTEIDYINGAISRKGKKYGVVTPYCDFLTQLVHSKEEILGAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 7e-142 100
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 5e-142 100