Gene Information

Name : EF0485 (EF0485)
Accession : NP_814266.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Virulence
Product : aggregation substance
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 450206 - 454123 bp
Length : 3918 bp
Strand : +
Note : similar to GB:J03600, GB:J03571, SP:P09917, PID:187167, PID:187169, PID:187193, and PID:388525; identified by sequence similarity

DNA sequence :
TTGAAGCAACAAATGAAAGCAAAAAAACAATATAAGACATATAAAGCTAAGAATCACTGGGTAACTGTCCCTATTCTTTT
TCTAAGTGTGTTAGGAGCCGTAGGATTAGCTACTGATAATGTACAAGCCGCGGAATTAGATACGCAACCAGAAACAACGA
CGGTTCAACCCAATAACCCCGACCTGCAGTCAGAAAAGGAAACACCTAAAACGGCAGTATCTGAAGAAGCAACAGTACAA
AAAGACACTACTTCTCAACCGACCAAAGTAGAAGAAGTAGCGCCAGAAAATAAAGGTACTGAACAAAGTTCAGCTACCCC
AAATGATACCACAAACGCGCAACAACCAACAGTAGGAGCTGAAAAATCAGCACAAGAACAACCAGTAGTAAGCCCTGAAA
CAACCAATGAACCTCTAGGGCAGCCAACAGAAGTTGCACCAGCTGAAAATGAAGTGAATAAATCAACGTCCATTCCTAAA
GAATTTGAAACACCAGACGTTGATAAAGCAGTTGATGAAGTAAAAAAAGATCCAAACATTACCGTTGTTGAAAAACCAGC
AGAAGACTTAGGCAACGTTTCTTCTAAAGATTTAGCTGCAAAAGAAAAAGAAGTAGACCAACTACAAAAAGAACAAGCGA
AAAAGATTGCCCAACAAGCAGCTGAATTAAAAGCCAAAAATGAAAAAATTGCCAAAGAAAATGCAGAAATTGCGGCAAAA
AACAAAGCAGAAAAAGAGCGTTATGAAAAAGAAGTCGCTGAATACAACAAGCATAAGAACGAAAACAGCTATGTCAATGA
AGCGATTAGTAAAAACCTAGTGTTCGATCAATCTGTCGTGACGAAAGACACTAAAATTTCGTCGATTAAAGGCGGAAAAT
TTATCAAAGCAACTGATTTTAATAAAGTAAATGCAGGGGATTCAAAAGATATCTTTACAAAATTACGGAAAGATATGGGC
GGGAAAGTTACTGGCAACTTCCAGAATTCCTTTGTAAAAGAGGCAAATCTTGGGTCTAATGGTGGGTATGCGGTTCTTTT
AGAAAAAAATAAACCAGTGACAGTGACCTATACAGGACTAAACGCTAGTTATTTAGGACGTAAAATTACAAAAGCAGAAT
TTGTTTATGAACTACAATCCTCACCAAGCCAAAGTGGAACGTTAAATGCAGTATTTTCAAACGATCCGATTATCACGGCT
TTTATTGGTACAAACAGAGTCAATGGTAAGGATGTTAAAACACGCTTAACGATTAAGTTCTTTGATGCGTCAGGTAAAGA
AGTACTACCAGATAAAGATAGTCCATTTGCGTATGCGCTGTCTTCTTTAAATTCAAGTTTAACGAATAAAGGTGGCCATG
CGGAATTTGTTTCTGATTTTGGGGCGAACAATGCGTTCAAATACATTAATGGTTCGTATGTGAAAAAACAAGCGGATGGA
AAATTTTACTCACCGGAAGATATTGACTATGGCACAGGACCTTCTGGATTGAAAAATAGTGATTGGGACGCTGTAGGTCA
CAAGAATGCCTACTTTGGTTCAGGTGTAGGTCTAGCCAATGGGCGTATTTCCTTTTCTTTTGGTATGACAACAAAAGGAA
AAAGTAATGTGCCTGTATCTAGTGCGCAATGGTTTGCCTTTAGTACTAACTTAAATGCGCAATCAGTGAAGCCTATTTTC
AATTATGGGAATCCAAAAGAACCAGAAAAAGCAACGATTGAATTCAATCGATACAAAGCCAATGTCGTTCCTGTACTTGT
GCCAAATAAAGAAGTCACTGATGGCCAGAAAAATGTCAATGATTTAAATGTGAAGCGTGGCGATTCTTTACAATACATTG
TGACAGGGGATACGACAGAACTTGCCAAAGTAGATCCAAAAACAGTAACCAAACAAGGGATTCGAGATACCTTTGATGCA
GAAAAAGTGACGATTGATTTATCCAAAGTGAAAGTTTATCAAGCAGACGCAAGTCTAAACGAGAAAGACTCAAAAGCTGT
TGCTGCAGCAATTAATTCAGGAAGAGCTAAAGACGTGACTGCTTCTTATGATCTTCATTTAGATCAAAACACCGTCACAG
CAATGATGAAAACCAACGCAGACGGTTCCATTGTTTTAGCAATGGGGTATAAATATTTACTTGTCTTGCCGTTTGTAGTG
AAAAATGTGGAAGGCGATTTTGAAAATACAGCTGTTCAGCTGACAAACGATGGTGAAACGGTAACAAATACAGTGATTAA
CCATGTGCCAGGTAGTAATCCTTCCAAAGATGTAAAAGCAGATAAAAACGGTACAGTTGGCAGTGTTTCGCTACATGACA
AAGATATTCCGTTACAGACAAAAATTTATTATGAAGTGAAATCTTCCGAACGTCCAGCTAACTATGGCGGAATTACCAAA
GAATGGGGCATGAATGATGTCTTGGACACGACCCATGATCGTTTCACAGGGAAATGGCACGCTATTACGAATTATGACCT
TAAAGTAGGGGATAAAACGTTAAAAGCAGGAACAGATATTTCTGCCTACATTCTTTTAGAAAACAAAGACAATAAAGACT
TAACGTTTACGATGAATCAAGCACTATTGGCCGCCTTAAATGAAGGAAGCAATAAAGTAGGCAAACAAGCTTGGTCTGTG
TATCTGGAAGTCGAACGGATTAAAACAGGTGACGTAGAAAACACGCAAACAGAAAACTACAACAAAGAGCTGATGCGTTC
TAATACCGTGGTGACGCATACGCCTGATGATCCAAAACCAACCAAAGCCGTTCATAACAAGAAAGGGGAAGATATTAACC
ATGGAAAAGTTGCTCGTGGTGATGTTCTTTCTTATGAAATGACCTGGGACTTAAAAGGGTACGATAAAGACTTTGCCTTT
GATACAGTCGATCTTGCGACAGGCGTTTCTTTCTTCGATGATTACGATGAAACGAAGGTGACACCAATCAAAGACTTACT
TCGTGTCAAAGATTCTAAAGGGGTAGACATTACGAACCAGTTCACGATCTCATGGGACGATGCCAAAGGCACGGTGACAA
TCTCTGCCAAAGACCCACAAGCCTTTATTCTAGCGCATGGTGGGCAAGAATTGCGTGTAACGCTCCCTACAAAAGTCAAA
GCCGATGTTTCTGGGGATATTTATAATTCAGCGGAACAAAATACATTTGGCCAACGAATTAAAACCAATACCGTTGTCAA
CCATATTCCAAAAGTGAACCCTAAAAAAGACGTGGTTATTAAAGTCGGTGACAAACAAAGCCAAAATGGCGCCACAATCA
AATTAGGGGAGAAATTCTTCTATGAATTCACAAGTAGTGACATTCCTGCAGAATACGCTGGTGTTGTGGAAGAATGGTCG
ATTAGCGATAAACTAGACGTCAAACATGACAAATTTAGTGGCCAATGGTCTGTGTTTGCCAATTCTAATTTTGTTTTAGC
AGACGGAACCAAAGTGAATAAAGGGGACGACATTTCGAAACTATTCACGATGACCTTTGAACAAGGGGTAGTGAAAATCA
CGGCCAGTCAAGCCTTTTTGGATGCGATGAATCTAAAAGAAAACAAAAACGTTGCGCACTCATGGAAAGCGTTCATTGGT
GTAGAACGAATTGCGGCAGGAGACGTTTACAACACGATTGAAGAATCTTTCAATAATGAAACGATCAAGACTAATACGGT
AGTGACGCATACGCCAGAAAAACCACAAACACCACCAGAAAAAACAGTGATCGTGCCACCAACACCAAAAACACCACAAG
CACCAGTAGAGCCATTAGTGGTAGAAAAGGCAAGTGTAGAGCCAGAATTGCCACAAACAGGCGAAAAACAAAATGTCTTA
TTAACGGTAGCTGGAAGTTTAGCTGCAATGCTTGGCTTAGCAGGCTTAGGCTTTAAACGTAGAAAAGAAACAAAATAA

Protein sequence :
MKQQMKAKKQYKTYKAKNHWVTVPILFLSVLGAVGLATDNVQAAELDTQPETTTVQPNNPDLQSEKETPKTAVSEEATVQ
KDTTSQPTKVEEVAPENKGTEQSSATPNDTTNAQQPTVGAEKSAQEQPVVSPETTNEPLGQPTEVAPAENEVNKSTSIPK
EFETPDVDKAVDEVKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAK
NKAEKERYEKEVAEYNKHKNENSYVNEAISKNLVFDQSVVTKDTKISSIKGGKFIKATDFNKVNAGDSKDIFTKLRKDMG
GKVTGNFQNSFVKEANLGSNGGYAVLLEKNKPVTVTYTGLNASYLGRKITKAEFVYELQSSPSQSGTLNAVFSNDPIITA
FIGTNRVNGKDVKTRLTIKFFDASGKEVLPDKDSPFAYALSSLNSSLTNKGGHAEFVSDFGANNAFKYINGSYVKKQADG
KFYSPEDIDYGTGPSGLKNSDWDAVGHKNAYFGSGVGLANGRISFSFGMTTKGKSNVPVSSAQWFAFSTNLNAQSVKPIF
NYGNPKEPEKATIEFNRYKANVVPVLVPNKEVTDGQKNVNDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQGIRDTFDA
EKVTIDLSKVKVYQADASLNEKDSKAVAAAINSGRAKDVTASYDLHLDQNTVTAMMKTNADGSIVLAMGYKYLLVLPFVV
KNVEGDFENTAVQLTNDGETVTNTVINHVPGSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERPANYGGITK
EWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNKVGKQAWSV
YLEVERIKTGDVENTQTENYNKELMRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLKGYDKDFAF
DTVDLATGVSFFDDYDETKVTPIKDLLRVKDSKGVDITNQFTISWDDAKGTVTISAKDPQAFILAHGGQELRVTLPTKVK
ADVSGDIYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEYAGVVEEWS
ISDKLDVKHDKFSGQWSVFANSNFVLADGTKVNKGDDISKLFTMTFEQGVVKITASQAFLDAMNLKENKNVAHSWKAFIG
VERIAAGDVYNTIEESFNNETIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVEPELPQTGEKQNVL
LTVAGSLAAMLGLAGLGFKRRKETK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0005 AAM75211.1 EF0005 Not tested Not named Protein 0.0 100
EF0485 NP_814266.1 aggregation substance Virulence Not named Protein 0.0 100

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EF0485 NP_814266.1 aggregation substance VFG2172 Protein 0.0 100
EF0485 NP_814266.1 aggregation substance VFG2164 Protein 0.0 97
EF0485 NP_814266.1 aggregation substance VFG2171 Protein 0.0 91
EF0485 NP_814266.1 aggregation substance VFG2173 Protein 0.0 82