Gene Information

Name : nrdE (EF0471)
Accession : NP_814255.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 438984 - 441143 bp
Length : 2160 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGAGTCTAAAAGAAATTAAAGATGTCAGCTATTTCAAACTGAATAACGAGATTAACCGTCCTGTTGATGGTCAAATCCC
TTTAAATAAAGATAAAGAAGCACTCGCAGCCTTCTTTAAAGAAAATGTAGAACCGAATACACGTAAATTCAGCTCTGCTG
AAGAAAAAATCAACTTTTTAATGAAAGAAGATTTTATTGAAACTGAATTCATCGAAAAATATTCAATGGACTTTATTGAA
AAATTATATGCTTTCTTAGATGAACAACATTTCCAATTCAAGTCTTTCATGGCGGCTTATAAATTTTATTCTCAATACGC
TTTAAAGAACAACGCCGGAACAGAGTATTTAGAAACATATGAAGATCGGGTTGCCTTTAATGCCTTGTATTTTGCGGATG
GCGATGAAGAGTTGGCTTTAACATTGGCGGATGAAATGATCCATCAACGGTATCAACCAGCCACACCTTCTTTCTTAAAC
GCTGGGCGTAAACGTCGAGGTGAATTGGTTTCTTGTTTCTTAGTTCAAGTAACAGATGATATGAACAGCATTGGGCGTTC
AATTAATTCTGCCCTTCAATTATCACGAATCGGCGGCGGCGTAGGAATTACTCTTTCCAACTTACGTGAAGCGGGCGCAC
CAATCAAAGGTTATGATGGCGCAGCAAGTGGTGTTGTCCCTGTTATGAAATTATTTGAAGATAGCTTTAGCTACTCTAAC
CAACTAGGTCAACGTCAAGGTGCTGGTGTGGTTTATCTAAATGTCTTCCATCCAGATATTGAAATGTTCTTATCTGCTAA
AAAAGAAAACGCTGATGAAAAAATCCGTGTAAAAACGTTGTCTCTTGGTGTTATTGTTCCAGATAAATTTTACGAATTAA
CACGTAACAACGAAGATATGTATTTATTTAGTCCTTATAGTGTGGAACGTGAATATGGTGTGCCTTATTCCTATGTAGAT
ATTACCAAAGAATATGATAACCTAGTGGCCAATCCAAACATACGTAAACGTAAAATTAAAGCCCGTGACTTAGAAAATGA
AATTTCTAAATTACAACAAGAATCTGGCTATCCTTATATCATCAATATTGATACAGCTAACAAAAACAATCCGATTGATG
GCAAGATTATCATGAGTAACTTATGTTCTGAAATTCTTCAAGTTCAAACGCCTTCTGTTATTAATGGGAAACAAGAATAT
GAAGTTTTAGGAACAGATATTAGTTGTAACTTAGGTTCAACTAACATTGTTAATTTAATGGAAAGTCCTGACTTTGGAAA
ATCTGTCCGCGCTATGACGCGTGCGTTAACTTTTGTAACAGATGCTTCTGAAATTGATGTCGTGCCAACTATCCAAAATG
GAAATCGTTTAAGCCATACAATCGGACTAGGCGCAATGGGCTTACACACCTTCTTCGCTAAAAATCATATGGAATACGGC
TCTGAAGAATCATTAGACTTTACAGACATTTATTTCATGTTATTAAATTACTGGACTTTAATGGAAAGTAACCAAATTGC
GAAAGAACGTAACCAAGTCTTCCATAATTTTGAAAAATCAGATTATGCTTCTGGTGCTTACTTCGATAAATATATTGAAG
GCAACTTTACACCAAAATTTGATAAAGTGAAAGAAATTTTCAAAGACATTCAGATTCCAACGGCTGAAGATTGGGCTGCG
TTACGCGATGCTGTGAAAAAAGATGGTCTTTATCATCAAAATCGTTTAGCCGTAGCGCCAAATGGTTCAATTTCATATAT
TAATGATACTAGTGCCAGCATTCATCCAATTACTCGTATGATTGAAGAACGTCAAGAGAAGAAAATTGGTAAGATTTACT
ATCCAGCGCCTTATTTAGCTAATGATACAATCCCTTACTATACTTCTGCTTACGACATGGATATGCGCAAAGTGATTGAT
GTCTACGCAACAGCGCAACAACACGTTGATCAAGGAATGAGTTTAACCTTGTTTATGCGTTCAGAAATCCCTGAAGGCTT
GTATGAATGGAAAGAAACACCAAAACAAACAACCCGTGACTTGAACATTTTACGTCATTATGCGTTCAACAAAGGGATTA
AATCAATTTACTATATTCGTACATTTACAGATGATGCTGAAGAAATTGGCAGCAATCAATGTGAGTCTTGCGTGATTTAA

Protein sequence :
MSLKEIKDVSYFKLNNEINRPVDGQIPLNKDKEALAAFFKENVEPNTRKFSSAEEKINFLMKEDFIETEFIEKYSMDFIE
KLYAFLDEQHFQFKSFMAAYKFYSQYALKNNAGTEYLETYEDRVAFNALYFADGDEELALTLADEMIHQRYQPATPSFLN
AGRKRRGELVSCFLVQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYDGAASGVVPVMKLFEDSFSYSN
QLGQRQGAGVVYLNVFHPDIEMFLSAKKENADEKIRVKTLSLGVIVPDKFYELTRNNEDMYLFSPYSVEREYGVPYSYVD
ITKEYDNLVANPNIRKRKIKARDLENEISKLQQESGYPYIINIDTANKNNPIDGKIIMSNLCSEILQVQTPSVINGKQEY
EVLGTDISCNLGSTNIVNLMESPDFGKSVRAMTRALTFVTDASEIDVVPTIQNGNRLSHTIGLGAMGLHTFFAKNHMEYG
SEESLDFTDIYFMLLNYWTLMESNQIAKERNQVFHNFEKSDYASGAYFDKYIEGNFTPKFDKVKEIFKDIQIPTAEDWAA
LRDAVKKDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLANDTIPYYTSAYDMDMRKVID
VYATAQQHVDQGMSLTLFMRSEIPEGLYEWKETPKQTTRDLNILRHYAFNKGIKSIYYIRTFTDDAEEIGSNQCESCVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 52