Gene Information

Name : nrdF (EF0470)
Accession : NP_814254.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 437818 - 438783 bp
Length : 966 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGCAACGTATTATGAAGCAATTAACTGGAACGCCATTGAAGACGTCATTGATAAATCCACTTGGGAAAAATTAACCGA
ACAATTTTGGTTAGATACACGGATTCCGTTATCCAATGACTTAGATGATTGGCGGACTCTTTCCGATTTAGAAAAAACTA
CTGTCGGCTACGTTTTCGGCGGTTTAACTTTATTAGATACTGTTCAATCAGAAAGCGGCATGGATCAACTGAGAAATGAT
GTGCGGACGCCTCATGAAGAAGCCGTCTTAAATAACATCCAATTCATGGAATCTGTCCATGCCAAAAGTTATTCTTCTAT
CTTCAGTACATTAAATACAAAAAAAGAGATTGATGATATTTTTGAGTGGACAAATACCAACAAACACCTGCAATATAAAG
CAGAACGGATTAACGAAATTTATAAAAACGGTACTCCGTTAGAGAAAAAAATTGCTAGTGTATTTTTAGAAACGTTTTTA
TTCTATTCTGGGTTTTACACTCCTCTTTACTATTTAGGAAACAATAAACTAGCGAACGTCGCTGAAATTATTAAATTGAT
TATCCGTGATGAATCAGTGCACGGCACGTATATTGGCTATAAATTCCAATTAGGATTTAATGAATTACCAGAAGATGAGC
AAGATAAACTAAAAGACTGGATGTATAATTTACTTTACGAATTGTACGAAAACGAAGAACGTTATACAGAAGAATTATAT
GATGACTTAGGTTGGACCGAAGAAGTAAAAACCTTTTTACGTTACAACGCCAACAAAGCTTTAATGAACTTAGGTATGGA
TCCCTTATTTGCGGATACAGCCAATGATGTGAACCCGATTGTAATGAATGGTATTTCGACAGGAACTAGCAACCATGACT
TCTTCTCCCAAGTAGGAAATGGCTATTTACTAGGAACAGTTGAAGCCATGAAAGATGATGACTATCTTTACGGTTTAGAT
AAATAG

Protein sequence :
MATYYEAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRTLSDLEKTTVGYVFGGLTLLDTVQSESGMDQLRND
VRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIDDIFEWTNTNKHLQYKAERINEIYKNGTPLEKKIASVFLETFL
FYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQDKLKDWMYNLLYELYENEERYTEELY
DDLGWTEEVKTFLRYNANKALMNLGMDPLFADTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMKDDDYLYGLD
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-67 52