Gene Information

Name : serS-2 (EF3292)
Accession : NP_816887.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 3172906 - 3174177 bp
Length : 1272 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATGTAAAAATGATGCGTCAAAATTTTGACGAAGTAAAAGCAAAGCTACAAACCCGTGGCGTGAAAGAAGAAAT
CTTAGTGGAATTTCTGCGTTTAGATGAAAGTCGCCGTGATTTATTAGTCAAAGTCGAAGAAATGAAAAAATACCGGAATG
ATGTGTCTGCTGAAATTGCTCAATTAAAACGAAACAAAGAAGATGCAACGGCCAAAATCGCGGAAATGAAAGAAGTCGGC
GGCAATATTAAAGCATTAGATGCAGAAATTAACGCTATTGACGAAGAGCTACGTGGGATCACAACTACTTTACCGAATTT
GCCAGATGATTCTGTGCCTGTTGGTGCTGGTGAAGAAGAAAATGTAGAAGTACGTCGTTGGAGTGAACCAAGAACTTTTG
CTTTTGAACCAAAACCACACTGGGAAGTCGCTGAAAACTTAGGCATTCTAGATTTTGAACGTGGTGCCAAAGTAGCTGGT
AGCCGTTTTGTTTATTACAAAGGCTTAGGTGCACGCTTAGAACGTGCGTTATACAACTTCATGTTAGATTTACATGTTTA
TGAACATGGCTATACAGAAATGATTACGCCTTATATCGTTAATGACACCGCCATGTTCGGGACTGGCCAATTTCCTAAAT
TTAAAGAAGATGTCTTCCAATTACAAGATACGGATTTAACGTTAATTCCAACTGCGGAAGTCCCTTTAACCAATTACTAC
AACAATGAAATTTTAGATGGCAAGGATTTACCGATTTACTTTACGGCCTTGAGCCCTTCTTTCCGTTCTGAAGCTGGTAG
CGCTGGTCGTGACACACGAGGATTAATTCGTTTACACCAATTTAATAAAGTCGAAATGGTTAAATTTAGTGATGCAGAGC
ATTCTTATGAGGAATTAGAAAAAATGACGAATAATGCCGAAGAAATTCTGCAAAAACTGGGATTACCTTACCGTGTCATG
GCTCTTTCAACAGGTGACATGGGCTTCTCAGCTGCGAAAACTTATGACTTGGAAGTTTGGATTCCTGCTCAAGAGACGTA
CCGTGAAATCAGTTCATGCTCAAACTGTGAAGATTTCCAAGCGCGCCGTGCGATGATTCGTTACCGTGATGAAAATGATA
AAGTCCAATATGCGCATACACTCAATGGTTCTGGTTTAGCCGTAGGACGGACAGTCGCTGCTATTTTAGAAAACTACCAA
AACGAAGATGGCTCTGTAACTGTACCAGAAGTCCTAGTTCCTTACATGGGTAACCTAACAGTTATTAAATAA

Protein sequence :
MLDVKMMRQNFDEVKAKLQTRGVKEEILVEFLRLDESRRDLLVKVEEMKKYRNDVSAEIAQLKRNKEDATAKIAEMKEVG
GNIKALDAEINAIDEELRGITTTLPNLPDDSVPVGAGEEENVEVRRWSEPRTFAFEPKPHWEVAENLGILDFERGAKVAG
SRFVYYKGLGARLERALYNFMLDLHVYEHGYTEMITPYIVNDTAMFGTGQFPKFKEDVFQLQDTDLTLIPTAEVPLTNYY
NNEILDGKDLPIYFTALSPSFRSEAGSAGRDTRGLIRLHQFNKVEMVKFSDAEHSYEELEKMTNNAEEILQKLGLPYRVM
ALSTGDMGFSAAKTYDLEVWIPAQETYREISSCSNCEDFQARRAMIRYRDENDKVQYAHTLNGSGLAVGRTVAAILENYQ
NEDGSVTVPEVLVPYMGNLTVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-152 74