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Name : metC (EF0290) Accession : NP_814082.1 Strain : Enterococcus faecalis V583 Genome accession: NC_004668 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 274324 - 275460 bp Length : 1137 bp Strand : + Note : catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine DNA sequence : ATGAAATTCAATACCAAATTAATTCATGGCGGCATTAGTAAAGACACAACAACAGGTGCAGTGAGTGTTCCTATTTATCA AACGTCAACCTTTGAACAAAATGGCGTGGGCCAGCCAAAAGAATATGAATATTCTCGTTCAGGTAATCCCACACGTCACG CGTTAGAAACCTTAATCGCTGAGTTAGAAGGTGGGAGCCATGGCTTTGCGTTTAGCTCAGGCTTAGCTGGTATCCATGCA ATCATTTCTATGTTTGGACCCGAAGATCATATTTTATTAGGTGACGATGTCTATGGGGGGAGTTTCCGTTTATTGGATAA AGTATTTGTAGCAAATGGGTTAAGCTACACGATTGTAAACGCCAGCGACTTATCAACAATTGAAGCCGCAATTCAGCCAA ATACAAAAGCCTTGTTTTTGGAAACACCAAGTAATCCACTGTTAAAAATTACAGATATTGAAGCGGCAGCTAAGCTTGCT AAAAAACATCAGTTGTTAACTATTGTCGATAATACATTTGCGACACCTTATTTTCAACGGCCGTTAGCGTTAGGTGCTGA TATTGTGGTTCACAGCGGGACAAAATATTTAGGGGGCCATAGTGATGTAGTCTCTGGTTTAGTCGTAACGAATCATCCAG AAAGCGCAGAAAAGATTGCCTTTTTACAAAATGCGATTGGTGCTGTTTTAGGACCACATGATAGTTGGCTGGTCCAACGT AGTTTAAAAACATTAGGCGTCCGGATGGCAGCGCATGCCCAAAATGCTCAAAAAATCGCAGAATTTTTAGAAGCGCATCC AGCGGTAGCAACGGTGTATTATCCAGGACTAGCGAGTCATCCTGGTCACGAAATTGCGCAAAAACAGATGTCGGGATTTA GTGGCATGATTTCTTTTGAATTAGCCAAGGATGAGCAAGTCGTTCCTTTCGTAGAAGCGTTGGAAATTTTTACTTTAGCG GAAAGTTTAGGTGGCGTAGAAAGTTTAATTGAAGTACCTGCCATTATGACTCACGCATCTATCCCCAAAGAAAATCGTGA AGCCGTGGGAATTAAAGATGGACTCATTCGTTTATCTGTAGGAATTGAAGCAGTCGAAGATTTATTGGCTGATTTAGAAA AGGGATTACAAGCATAA Protein sequence : MKFNTKLIHGGISKDTTTGAVSVPIYQTSTFEQNGVGQPKEYEYSRSGNPTRHALETLIAELEGGSHGFAFSSGLAGIHA IISMFGPEDHILLGDDVYGGSFRLLDKVFVANGLSYTIVNASDLSTIEAAIQPNTKALFLETPSNPLLKITDIEAAAKLA KKHQLLTIVDNTFATPYFQRPLALGADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKIAFLQNAIGAVLGPHDSWLVQR SLKTLGVRMAAHAQNAQKIAEFLEAHPAVATVYYPGLASHPGHEIAQKQMSGFSGMISFELAKDEQVVPFVEALEIFTLA ESLGGVESLIEVPAIMTHASIPKENREAVGIKDGLIRLSVGIEAVEDLLADLEKGLQA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-93 | 53 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 1e-94 | 53 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 4e-72 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| metC | NP_814082.1 | cystathionine gamma-synthase | BAC0207 | Protein | 9e-69 | 44 |
