Gene Information

Name : smpB (EF2616)
Accession : NP_816255.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 2530861 - 2531325 bp
Length : 465 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGCCAAAAGGGGAAGGAAAATTAATCGCACAAAACCGCAAAGCTAGACATGATTATTCAATTATCGATACGGTTGAAGC
TGGGCTTGTTTTACAAGGAACAGAAATCAAATCTATTCGAAATGGTCGTATCAATTTAAAAGATGGTTTTGCACGAATTC
GAAACGGAGAAGCCTTTTTGTATAATGTTCATATTAGTCCATATGAACAAGGCAATATTTTTAATCATGACCCATTACGT
ACCAGAAAATTATTATTACACAAAAAACAAATTAATAAGTTAATCGGCGAAACCAAAAATACAGGTATCACATTAGTACC
TTTGAAGGTCTATATTAAAGACGGCTATGCCAAAGTTTTGATTGGTTTAGCTAAAGGGAAAAAGCAGTACGACAAGCGTG
AAGACTTGAAACGTAAGGAAGTTGACCGACAAATCAGCCGAACATTAAAAAATAACCGACGTTAA

Protein sequence :
MPKGEGKLIAQNRKARHDYSIIDTVEAGLVLQGTEIKSIRNGRINLKDGFARIRNGEAFLYNVHISPYEQGNIFNHDPLR
TRKLLLHKKQINKLIGETKNTGITLVPLKVYIKDGYAKVLIGLAKGKKQYDKREDLKRKEVDRQISRTLKNNRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 6e-43 63
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 5e-33 50
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 9e-26 44