Gene Information

Name : EF2445 (EF2445)
Accession : NP_816093.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 2362785 - 2363726 bp
Length : 942 bp
Strand : +
Note : catalyzes the formation of 2-dehydropantoate from (R)-pantoate

DNA sequence :
ATGAAAATTGCAATTGCTGGTGCCGGCGCTATGGGCAGCCGTTTAGGAATTATGTTGCATCAAGGCGGAAATGATGTAAC
TTTAATCGATCAATGGCCCGCGCACATTGAAGCTATTCGTAAAAATGGTTTAATCGCTGATTTTAACGGAGAAGAAGTTG
TCGCGAACCTACCAATCTTCTCACCAGAAGAAATTGACCATCAAAATGAACAAGTAGATTTAATTATCGCTTTAACCAAA
GCACAACAATTAGATGCAATGTTTAAAGCGATTCAACCAATGATTACTGAAAAAACGTATGTACTATGTTTATTAAATGG
CTTAGGTCATGAAGATGTACTAGAAAAATATGTACCAAAAGAAAACATCTTGGTTGGCATTACCATGTGGACAGCTGGTT
TAGAAGGACCGGGACGTGTTAAACTTTTAGGTGATGGCGAAATTGAATTAGAAAATATTGATCCTTCTGGTAAAAAATTT
GCTTTAGAAGTCGTTGATGTCTTCCAAAAAGCTGGTTTAAATCCAAGCTATAGTAGCAATGTTCGCTACTCTATTTGGCG
GAAAGCCTGTGTCAATGGCACGCTAAACGGTTTGTGTACAATCCTTGATTGTAATATTGCCGAATTTGGCGCACTACCTG
TTAGTGAATCCCTTGTTAAAACATTAATCAGTGAATTTGCAGCAGTCGCAGAAAAAGAAGCCATTTATTTAGATCAAGCA
GAAGTCTATACACATATTGTTCAAACTTATGATCCAAATGGCATTGGCTTGCACTATCCGTCTATGTATCAAGATTTAAT
TAAAAATCATCGTCTCACAGAAATTGATTACATTAATGGTGCCGTTTGGCGCAAAGGACAAAAATACAACGTAGCAACAC
CTTTCTGTGCCATGTTGACACAGCTTGTTCACGGAAAAGAAGAACTATTAGGAGCTAAATAA

Protein sequence :
MKIAIAGAGAMGSRLGIMLHQGGNDVTLIDQWPAHIEAIRKNGLIADFNGEEVVANLPIFSPEEIDHQNEQVDLIIALTK
AQQLDAMFKAIQPMITEKTYVLCLLNGLGHEDVLEKYVPKENILVGITMWTAGLEGPGRVKLLGDGEIELENIDPSGKKF
ALEVVDVFQKAGLNPSYSSNVRYSIWRKACVNGTLNGLCTILDCNIAEFGALPVSESLVKTLISEFAAVAEKEAIYLDQA
EVYTHIVQTYDPNGIGLHYPSMYQDLIKNHRLTEIDYINGAVWRKGQKYNVATPFCAMLTQLVHGKEELLGAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 6e-86 60
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 4e-86 60