Gene Information

Name : EF0253 (EF0253)
Accession : NP_814048.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 229558 - 231048 bp
Length : 1491 bp
Strand : +
Note : identified by match to TIGR protein family HMM TIGR01804

DNA sequence :
ATGAGTAAAAAAGAAATAAATCAAGTAGTTGCCAGTAGCTATCAATTGTATATTAATGGAGAGTGGACAACAGGTAGTGG
TAACAAAATGATTGCTAGTTACAATCCTAGTAATGGCGAAAAATTAGCAGAATTTGTAGATGCCACAAATGCAGATGTGG
ATCGAGCTGTAGAAGCAGCCCAAGAAGCGTTTCAGACATGGAAAGATGTTGACGTTGTAACAAGAAGCAATCTTTTGTTG
AAAATTGCTGATTTGATTGAAGAAAATCAAGAACATTTGGCTATGGTGGAGACTTTAGATAATGGAAAACCGCTTCGGGA
AACGCAATCGATTGATGTCCCTGCCAGTGCAGACCATTTTCGGTATTTTGCTAGTGTGATTCGTGGAGAAGAAGGATCTG
TCAAAGAATTTGATAAGGATACGTTATCCATTGTTGTGAAAGAACCCATCGGTGTTGTGGGTCAAATTATTCCGTGGAAT
TTCCCCTTATTAATGGGTGCTTGGAAATTAGCACCAGCGTTGGCAGCAGGTAACACGGTTGTGATTCATCCGTCCTCGAG
CACATCATTAAGTCTGTTGGAATTGTTTAAAATTTTTGATCAAGTCTTGCCGAAAGGAGTAGTGAATTTAATCACCGGTC
GTGGTTCTGATTCAGGAAATTATATGTTGGCACATCCAGGGTTTGATAAGCTAGCTTTTACAGGCTCAACAGAGGTGGGG
TACACTGTCGCTAAAGCGGCGGCCGACCGCCTAATTCCAGCCACTTTAGAACTTGGCGGAAAATCAGCCAACATTATTTT
TGAAGATGCCAATTGGGAACGTGCATTAGAAGGCGTGCAGTTAGGGATTTTATTCAATCAAGGGCAAGTTTGTTGTGCTG
GGTCTCGTGTGTTCGTTCAGTCAGGTATTTATGATCAATTTGTAGAAGCTTTAAAGGAAAAGTTTGAACAAGTGAACGTT
GGTTTCCCGTGGGAAAAAGATGTTGAAATGGGCGCTCAGATCAATGAGCATCAATTGGAAGAAATTTTAAAATATGTCGA
AATTGGTGTGAAGGAAGGAGCTACGCTGATTACTGGTGGGCAACGTTTAACAGAAAATGGGCTAGACAAGGGGGCGTTTT
TAGCACCTACGTTATTAGCGAATGGTACGAATGCAATGTGTGTGGCCCAAGAAGAAATCTTTGGTCCTGTTGCAACAGTG
ATTAAATTTGAAACGGAAGAAGAAGTCATTCGTTTAGCTAATGATTCTGAATATGGTCTAGGTGGTGCCGTCTTTTCTCA
AGATATCAATGTGGCATTACGGGTTGCTCGTGGTGTACGGACAGGTCGAATGTGGGTCAACACATACAATCAATTGCCTG
CGGGCGCGCCATTTGGCGGTTATAAAAAATCAGGAATTGGTCGAGAAACGCATAAATCAATGCTAGATGCTTATACGCAA
ATGAAAAATATTTACATTGTGACAAAAGAAGAAGCAGATGGACTGTATTAA

Protein sequence :
MSKKEINQVVASSYQLYINGEWTTGSGNKMIASYNPSNGEKLAEFVDATNADVDRAVEAAQEAFQTWKDVDVVTRSNLLL
KIADLIEENQEHLAMVETLDNGKPLRETQSIDVPASADHFRYFASVIRGEEGSVKEFDKDTLSIVVKEPIGVVGQIIPWN
FPLLMGAWKLAPALAAGNTVVIHPSSSTSLSLLELFKIFDQVLPKGVVNLITGRGSDSGNYMLAHPGFDKLAFTGSTEVG
YTVAKAAADRLIPATLELGGKSANIIFEDANWERALEGVQLGILFNQGQVCCAGSRVFVQSGIYDQFVEALKEKFEQVNV
GFPWEKDVEMGAQINEHQLEEILKYVEIGVKEGATLITGGQRLTENGLDKGAFLAPTLLANGTNAMCVAQEEIFGPVATV
IKFETEEEVIRLANDSEYGLGGAVFSQDINVALRVARGVRTGRMWVNTYNQLPAGAPFGGYKKSGIGRETHKSMLDAYTQ
MKNIYIVTKEEADGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-99 49
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-102 48
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-102 48
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-102 48
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-102 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EF0253 NP_814048.1 aldehyde dehydrogenase VFG0082 Protein 2e-99 49