Gene Information

Name : topB-2 (EF2312)
Accession : NP_815968.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 2234375 - 2236492 bp
Length : 2118 bp
Strand : -
Note : similar to GP:8100667, and GP:10176010; identified by sequence similarity

DNA sequence :
ATGCAGTTAGTGATCGCGGAAAAACCGTCGGTCGGAATGGCGCTGTCTAAGGTATTAGGCGCGAAAAGCCGTGGCGATGG
TTACATGGAGGGCGGCGGCTGGCTGGTAAGCTGGTGCATCGGGCATCTGGTGGAACTTGCCCCCGCCGATGCCTATGACC
CCCGCTATTCCAAATGGAACTATGCCGACCTGCCGATTTTACCAAAACCTTGGCAGTTCCAGGTGCTGCCGGACACCAAA
AAACAGTTTGAAGTCTTAAAAACCCTGATACACCGGGCCGATGTCACCGCCTTAATCTGTGCAACAGACGCAGGACGCGA
GGGGGAACTCATTTTCCGCCTGACTTACCATCTGTGCGGCTGCACCAAACCCGTCAAGCGGCTGTGGATTTCCTCAATGG
AGGAAGCCGCAATCCAGAAAGGCTTCGACAACCTGCTGGACGGGAAGAACTACGACAATCTCTACGCCGCCGCTCTCTGC
CGCGCCAAGGCGGACTGGCTGATCGGCATCAACGGTACGCGCCTGTTTACCACACTGTACCAGGGCAAGTCCCTGAACGT
GGGCCGGGTGCAGACCCCGACGCTGGCACTGCTGGCAGAACGGGAAGCCGCTATTTCCGGCTTTCAGAAAGAGAAATTTT
ACACGGTGGAGTTGGAACTGGAGGGCTTTCGCGCCGCCAGTGAACGCTTTGCATCCAAAACGGACGCAGGCAGGCTGCGT
ACCGGCTGTGTGGGCAAGCCTGCAACGGTACAGACGGTTTCCCAAAAGGAGAAAACCGAGCGCCCGCCCAAGCTGTACGA
TTTGACTACCCTCCAACGGGAGGCCAACCGGCTGTTTGACTACACCGCCCAGCAGACGCTTGATTATCTGCAAGCCCTCT
ATGAAAAGCGGCTGGCGACCTACCCCCGCACGGACAGCCGGTACTTGACCGAGGATATGGCGGCGGGGCTTCCCGCGCTG
TGCCAGTCCGTCGCTGCGGCGCTGCCCTTTGCGGCAGATTTGTCCTTGCCGGTAAATGCCGCGCAGGTAATCGACAACAG
CAAAGTCACCGACCATCATGCCATCCTGCCCACGACAGAAGCGGCAAAAACCGACCTGTCCGCGCTGCCCTCCGGGGAGA
AAAACATCCTCTTTCTGGTTGCCGCCCGTCTGCTGTGCGCGGTAGGCGAACCCCATACCTATGCGGAAACCGCTGTCACA
CTGGAATGTGGCGGCGCTGTCTTTTCCGCAAAAGGCAAAACGGAAACCGCCGCAGGCTGGACGGCTATGGAGCAGGCTTT
CCATGCCACACTGAAAAAGAAACCGAAGCAGCCCGAACCCTCCCCGCCACTTCCTGCACTCACCAAGGGCCAGAAGCTGA
CCGCCGGGGGTGCATCCATCAAAGAGGGCGCGACCTCCCCACCGGCCCATTTTACCGAGGACACGCTTCTCTCCGCAATG
GAACACGCCAGTGCAAAGGAGTTTGCGAAACTGGAAGATGTGGAACACAAAGGACTTGGCACTCCGGCCACCCGTGCCGG
CGTGATTGAAAAGCTGGTGCGCTCCGGCTTTGTGGAACGGAAGAAAAAGCAGCTTTTCCCCACGGAAAAAGGCACGGAAC
TTATCAAGGTAATGCCTGATACGCTGAAATCCGTCAAGCTGACCGCTGAATGGGAGGAACGGCTGGGCGCGGTGGAGCGC
GGGGAACTCTCCCCGGAGGACTTTATGGCGGGCATTACCGCCATGCTCACCGAACTGGTAAAAAGCTATCAGGGCGTGAC
CGTGGCATCTGCCGCCCTGTCTGCATCCGGGCGCACGGTAATTGGTATCTGCCCCCGCTGCGGCAAAAACGTGGTGGAGG
GCAAAAAGAGCTTTTTCTGCGAGGGCTGGAACGCTGCGCCCGCCTGCGACTTTGCCCTGTGGAAGAACGACCGCTTTTTT
ACCAGCAAGCACAAGGAACTGACCCGCAAGGCTGCCGCCGCCCTGCTGAAAAAAGGGCGCGTTGCCATGACCGGCCTGTT
TTCCGAGAAAAAAGGCGTGCTCTATGATGCAATTGTTGTGATGGAGGACACCGGAGAGAAATTTGTTCGCTTTAAGCTGG
AATTTGACAATAACACACCTAAAAAGAAAGGAAACTGA

Protein sequence :
MQLVIAEKPSVGMALSKVLGAKSRGDGYMEGGGWLVSWCIGHLVELAPADAYDPRYSKWNYADLPILPKPWQFQVLPDTK
KQFEVLKTLIHRADVTALICATDAGREGELIFRLTYHLCGCTKPVKRLWISSMEEAAIQKGFDNLLDGKNYDNLYAAALC
RAKADWLIGINGTRLFTTLYQGKSLNVGRVQTPTLALLAEREAAISGFQKEKFYTVELELEGFRAASERFASKTDAGRLR
TGCVGKPATVQTVSQKEKTERPPKLYDLTTLQREANRLFDYTAQQTLDYLQALYEKRLATYPRTDSRYLTEDMAAGLPAL
CQSVAAALPFAADLSLPVNAAQVIDNSKVTDHHAILPTTEAAKTDLSALPSGEKNILFLVAARLLCAVGEPHTYAETAVT
LECGGAVFSAKGKTETAAGWTAMEQAFHATLKKKPKQPEPSPPLPALTKGQKLTAGGASIKEGATSPPAHFTEDTLLSAM
EHASAKEFAKLEDVEHKGLGTPATRAGVIEKLVRSGFVERKKKQLFPTEKGTELIKVMPDTLKSVKLTAEWEERLGAVER
GELSPEDFMAGITAMLTELVKSYQGVTVASAALSASGRTVIGICPRCGKNVVEGKKSFFCEGWNAAPACDFALWKNDRFF
TSKHKELTRKAAAALLKKGRVAMTGLFSEKKGVLYDAIVVMEDTGEKFVRFKLEFDNNTPKKKGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB-2 NP_815968.1 DNA topoisomerase III Not tested Not named Protein 0.0 100
EFAU085_00720 YP_008394244.1 DNA topoisomerase III Not tested Not named Protein 0.0 52