Gene Information

Name : vanW (EF2296)
Accession : NP_815953.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Resistance
Product : vancomycin B-type resistance protein VanW
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2720
EC number : -
Position : 2214956 - 2215783 bp
Length : 828 bp
Strand : -
Note : similar to GB:M94362, GB:M94363, SP:Q03252, PID:1054874, GB:M94362, GB:M94363, SP:Q03252, and PID:1054874; identified by sequence similarity

DNA sequence :
ATGAACAGAAAAAGATTGACACAGCGCTTCCCGTTCCTGCTTCCAATGAGACAAGCGCAGAGAAAAATATGCTTTTATGC
GGGAATGAGATTTGACGGCTGTTGCTATGCACAGACGATAGGAGAAAAAACGCTTCCCTATTTGCTCTTTGAAACGGATT
GTGCGTTATACAACCACAATACCGGATTTGACATGATATACCAAGAAAACAAGGTGTTCAACTTAAAGCTGGCGGCAAAG
ACCTTAAACGGCCTATTGATAAAACCGGGGGAAACCTTTTCTTTCTGGCGGCTGGTACGCCATGCGGACAAAGATACCCC
CTATAAAGACGGCCTTACGGTGGCCAATGGTAAGCTCACCACCATGTCGGGCGGCGGTATGTGCCAGATGAGCAATTTAC
TATTTTGGGTGTTCCTGCATACGCCATTGACAATTATCCAGCGCAGCGGTCACGTAGTAAAGGAGTTTCCAGAGCCAAAC
AGTGACGAGATCAAAGGGGTGGATGCAACCATCTCAGAGGGCTGGATTGATTTAAAAGTGCGAAACGATACCGACTGCAC
CTACCAAATATGGGTGACCCTAGATGATGAGAAAATCATCGGTCAGGTGTTCGCCGACAAACAGCCTCAAGCATTATACA
AAATTGCAAACGGCAGTATTCAGTATGTCCGTGAAAGTGGCGGGATTTATGAATATGCCAAGGTTGAACGGATGCAAGTT
GCCTTAGGTACCGGGGAAATAATAGATTGCAAGCTGCTTTATACAAACAAATGCAAAATCTGCTATCCCCTCCCGGAAAG
TGTGGATATTCAGGAGGCGAACCAATGA

Protein sequence :
MNRKRLTQRFPFLLPMRQAQRKICFYAGMRFDGCCYAQTIGEKTLPYLLFETDCALYNHNTGFDMIYQENKVFNLKLAAK
TLNGLLIKPGETFSFWRLVRHADKDTPYKDGLTVANGKLTTMSGGGMCQMSNLLFWVFLHTPLTIIQRSGHVVKEFPEPN
SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVFADKQPQALYKIANGSIQYVRESGGIYEYAKVERMQV
ALGTGEIIDCKLLYTNKCKICYPLPESVDIQEANQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanW NP_815953.1 vancomycin B-type resistance protein VanW Not tested Not named Protein 3e-129 100
vanWB YP_008394257.1 vancomycin B-type resistance protein VanW Not tested Not named Protein 9e-122 93

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vanW NP_815953.1 vancomycin B-type resistance protein VanW U35369.1.gene4.p01 Protein 1e-129 100
vanW NP_815953.1 vancomycin B-type resistance protein VanW AE016830.1.gene2252. Protein 1e-129 100
vanW NP_815953.1 vancomycin B-type resistance protein VanW AF310956.2.orf3.gene Protein 3e-122 94
vanW NP_815953.1 vancomycin B-type resistance protein VanW DQ212986.1.gene7.p01 Protein 4e-62 52
vanW NP_815953.1 vancomycin B-type resistance protein VanW AF253562.2.orf3.gene Protein 9e-45 46