Gene Information

Name : EF2295 (EF2295)
Accession : NP_815952.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Resistance
Product : D-specific alpha-keto acid dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 2213988 - 2214959 bp
Length : 972 bp
Strand : -
Note : similar to SP:Q47748, GB:X14831, GB:J03858, GB:S71326, GB:M76741, GB:M76742, GB:M76743, GB:M76744, GB:D12502, GB:M72238, GB:D90311, GB:D90313, SP:P13688, PID:179435, PID:179437, PID:219499, and PID:219501; identified by sequence similarity

DNA sequence :
ATGAGAAAAAGTATGGGCATTACTGTTTTTGGATGCGAGCAGGATGAGGCAAATGCTTTCCGCACCTTATCACCAGATTT
TCATATTATCCCTACGCTGATCAGTGATGCGATATCGGCAGACAACGCAAAATTGGCCGCTGGCAATCAATGCATTAGCG
TAGGCCATAAGTCCGAGGTTTCCGAGGCGACAATTCTTGCGCTGAGAAAGGTCGGGGTAAAATACATTTCTACCCGCAGC
ATCGGCTGCAATCACATTGATACGACTGCCGCCGAGAGAATGGGGATCTCGGTTGGCACAGTTGCGTATTCGCCGGACAG
CGTTGCGGATTATGCTTTGATGCTGATGCTGATGGCCATACGGGGTGCAAAGTCCACCATACACGCCGTGGCGCAACAAA
ATTTCAGACTGGATTGTGTCCGGGGGAAAGAGCTGCGGGATATGACTGTGGGAGTTATTGGAACCGGCCATATAGGGCAA
GCGGTCGTCAAAAGGCTGCGGGGATTTGGATGCCGTGTGCTAGCCTATGATAACAGCCGAAAAATTGAGGCAGATTATGT
CCAGCTTGATGAGCTTCTAAAAAACAGCGATATTGTTACGCTCCATGTGCCGCTTTGTGCGGATACCCGCCATCTGATCG
GCCAGAGGCAAATCGGAGAGATGAAGCAAGGCGCATTTTTAATCAACACTGGGCGCGGGGCGCTTGTCGATACCGGGTCG
CTGGTGGAGGCACTGGGAAGCGGAAAGCTGGGCGGTGCGGCACTGGATGTGTTGGAGGGCGAGGATCAGTTTGTTTATAC
CGACTGCTCGCAGAAAGTGCTTGACCATCCCTTTTTGTCGCAGCTCCTAAGGATGCCAAATGTGATCATCACACCCCATA
CGGCGTACTACACCGAGCGTGTGCTGCGAGATACCACAGAAAAAACAATCAGGAATTGTCTTAACTTTGAAAGGAGTTTA
CAGCATGAATAA

Protein sequence :
MRKSMGITVFGCEQDEANAFRTLSPDFHIIPTLISDAISADNAKLAAGNQCISVGHKSEVSEATILALRKVGVKYISTRS
IGCNHIDTTAAERMGISVGTVAYSPDSVADYALMLMLMAIRGAKSTIHAVAQQNFRLDCVRGKELRDMTVGVIGTGHIGQ
AVVKRLRGFGCRVLAYDNSRKIEADYVQLDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGS
LVEALGSGKLGGAALDVLEGEDQFVYTDCSQKVLDHPFLSQLLRMPNVIITPHTAYYTERVLRDTTEKTIRNCLNFERSL
QHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 6e-145 100
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 1e-139 95

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase U35369.1.gene5.p01 Protein 1e-144 99
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase AF310956.2.orf4.gene Protein 3e-140 95
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase NC_014475.1.orf2.gen Protein 2e-105 69
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase NC_005054.2598279.p0 Protein 2e-105 69
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase AF155139.2.orf4.gene Protein 8e-100 68
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase AF130997.1.orf3.gene Protein 4e-90 63
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase FJ349556.1.orf3.gene Protein 1e-95 62