Gene Information

Name : vanX (EF2293)
Accession : NP_815950.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Resistance
Product : D-alanyl-D-alanine dipeptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2173
EC number : -
Position : 2212353 - 2212961 bp
Length : 609 bp
Strand : -
Note : similar to GB:X14831, GB:J03858, GB:S71326, GB:M76741, GB:M76742, GB:M76743, GB:M76744, GB:D12502, GB:M72238, GB:D90311, GB:D90313, SP:P13688, PID:179435, PID:179437, PID:219499, PID:219501, GB:X55885, SP:P24390, and PID:34031; identified by sequence simi

DNA sequence :
ATGGAAAATGGTTTTTTGTTTTTAGATGAAATGTTGCATGGTGTTCGTTGGGATGCCAAGTACGCTACATGGGATAACTT
CACGGGAAAACCAGTGGATGGGTATGAGGTGAATCGCATCATCGGCACAAAGGCCGTGGCGCTTGCTCTGCGCGAAGCAC
AAATCCATGCGGCAGCCCTTGGCTACGGCTTGCTTTTATGGGATGGATATCGGCCAAAATCTGCGGTGGACTGTTTCCTG
CGTTGGGCGGCGCAGCCGGAGGACAACCTCACAAAAGAAAAATATTACCCCAATATTGAGCGAGCCGAGTTGATTACAAA
GGGCTATGTGGCCTCACAATCCAGCCATAGCCGTGGAAGCACAATTGATCTTACGCTCTACCACTTGGATACAGGGGAAC
TTGTTTCAATGGGAAGCAACTTCGATTTTATGGACGAACGGTCGCACCATACAGCAAAAGGGATAGGGAATGCAGAGGCA
CAAAATCGAAGATGCTTGCGTAAAATCATGGAAAGCAGCGGATTTCAGTCCTATCGCTTTGAATGGTGGCACTATAAGTT
GATTGATGAGCCATACCCCGATACCTATTTTAATTTTGCTGTTTCATAA

Protein sequence :
MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTKAVALALREAQIHAAALGYGLLLWDGYRPKSAVDCFL
RWAAQPEDNLTKEKYYPNIERAELITKGYVASQSSHSRGSTIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGNAEA
QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 1e-91 100
vanXB YP_008394260.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 2e-90 98

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase AE016830.1.gene2249. Protein 3e-92 100
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase U35369.1.gene7.p01 Protein 1e-91 99
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase AF310956.2.orf6.gene Protein 5e-91 98
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase NC_005054.2598281.p0 Protein 6e-73 75
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase M97297.gene.p01 Protein 6e-73 75
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase NC_014475.1.orf4.gen Protein 6e-73 75
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase FJ349556.1.orf5.gene Protein 1e-70 74
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase AF155139.2.orf6.gene Protein 1e-72 74
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase AF130997.1.orf5.gene Protein 1e-74 71
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase U82965.2.orf32.gene. Protein 2e-66 66