Gene Information

Name : secA (EF1763)
Accession : NP_815465.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1709114 - 1711651 bp
Length : 2538 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCAAATTTTTTGAAAAAAATGATCGAAAACGATAAAAAAGAATTAAGACGATTAGAAAAAATCGCCGATAAAATTGA
TGCACATGCAAGTGCAATGGAACAACTAAGCGATGAACAATTACGTGAAAAAACAGATGAATTTAAAGCCCGTTATCAAA
AAGGGGAAACCTTAGACGAACTATTACCAGAAGCGTTTGCGGTTGTCCGTGAAGCTGCTAAACGAGTACTAGGTTTATTC
CCGTACCGTGTCCAATTAATGGGTGGGATTGTGCTTCATGACGGGAACATTCCTGAAATGAGAACAGGTGAAGGGAAAAC
CTTGACTGCCACAATGCCTGTATACTTGAATGCACTATCTGGCGAAGGAGTACACGTTGTTACAGTTAATGAATACTTAG
CAACCCGTGACTCTAACGAAATGGGAGAATTATATAATTTCTTAGGCTTAAGCGTTGGCTTAAACATTAACTCTAAATCT
TCTGATGAAAAACGTGAAGCGTATAACTGTGATATCACTTATAGTACAAATAACGAATTAGGATTTGACTATTTGCGTGA
TAACATGGTTGTTTATCGCAGCCAAATGGTTCAACGTCCATTAAACTATGCAATTGTCGATGAAGTGGATTCAATCTTAA
TTGATGAAGCAAGAACCCCATTAATTATTTCTGGACAAGCTGAAAAATCGACAGCACTTTATACGCGTGCCGATAATTTT
GTCAAACGCTTAAAAGAAGATGAAGATTACAAAATTGATATTCAGTCTAAAACAATTGGTTTAACAGAAGCAGGTATTGA
AAAAGCTGAACAAACTTTTGGATTGGATAACCTTTACGATATTGAAAATACAGCATTAACGCACCATTTAGATCAAGCGT
TACGGGCAAACTATATCATGTTACTAGACATTGATTACGTGGTTCAAGACAATAAAGTCTTAATTGTTGACCAATTTACT
GGTCGTATCATGGATGGTCGTCGTTATTCTGATGGCTTGCATCAAGCGATTGAAGCAAAAGAAGGCGTCGAAATTGAAGA
TGAAACAAAGACAATGGCGACGATTACGTTCCAAAACTACTTCCGGATGTACAAAAAACTAGCCGGGATGACTGGTACTG
CTAAAACAGAAGAAGAAGAATTCCGTGAAATTTACAATATTCAAGTCATTCAAATCCCAACCAATCGTCCAATTATCCGT
GACGATCGTCCAGATTTACTTTATCCAACCTTAGAAAGTAAATTTAATGCAGTGGTGGAAGATATTAAAGAACGTTACCA
CAAAGGGCAACCAGTGTTGGTGGGGACTGTTGCGGTAGAAACGTCAGAATTACTTTCTGATAAATTAAACGCAGCTAAAA
TTCCTCATGAAGTATTAAATGCGAAAAATCACTTTAAAGAAGCCGAAATCATTATGAATGCCGGTCAAAAAGGCGCAGTT
ACAATTGCAACAAATATGGCTGGTCGTGGAACGGATATTAAACTTGGTTTAGGTGTACTTGAACTAGGTGGTCTAGCAGT
TATCGGGACAGAACGTCATGAGTCACGTCGTATTGATAATCAGTTGCGTGGACGTGCAGGACGTCAAGGGGATCCAGGGG
TTTCACAATTTTATTTATCTTTAGAAGATGACTTAATGAAACGCTTTGGTTCAGAACGAATTAAAACATTCTTAGAACGA
ATGAATGTGCAAGAAGAAGATGCAGTTATTCAAAGTAAAATGTTTACTCGCCAAGTAGAGTCTGCTCAAAAACGTGTGGA
AGGAAATAACTATGACACACGTAAAAATGTCTTACAATACGATGACGTGATGCGCGAGCAACGTGAAGTTATTTATGCGC
AACGACAAGAAGTAATTATGGAAGAAAATGACTTGTCTGATGTATTGATGGGCATGGTAAAACGGACGATTGGCCGAGTG
GTGGATAGCCATACACAATTAGAAAAAGAAGAATGGAATTTAGATGGGATTGTCGATTTTGCAGCCTCAACACTTGTCCA
TGAAGATACGATTTCTAAAAAAGATTTAGAAAATAAATCAGCTGAAGAAATCAAAGACTACTTAGTGGCACGTGCGCAAG
AAGTATTTGAAGAAAAATCTCAACAATTGAATGGCCAAGAACAATTGCTAGAATTTGAAAAAGTAGTCATCTTGCGTGTT
GTCGATACTAAATGGACAGATCACATTGATGCAATGGATCAATTACGCCAATCTGTCGGGTTACGTGCGTACGGTCAAAA
CAACCCATTAGTAGAATATCAAACAGAAGGTTATTCTATGTATAACAATATGGTGGGTTCAATCGAATATGAAGTAACAC
GTTTATTCATGAAATCGGAAATTCGCCAAAATGTCCAACGTGAGCAAGTAGCTCAAGGACAAGCGGAACATCCAGAAACA
GAACAAGATGCAGCTGCACAAAGCAACACAAGTGCGAAGCGTCAACCTGTGCGTGTAGATAAAAAAGTGGGCCGTAATGA
TTTATGCCCATGCGGAAGTGGCAAAAAATTCAAAAATTGTCATGGAAGAAACGCTTAA

Protein sequence :
MANFLKKMIENDKKELRRLEKIADKIDAHASAMEQLSDEQLREKTDEFKARYQKGETLDELLPEAFAVVREAAKRVLGLF
PYRVQLMGGIVLHDGNIPEMRTGEGKTLTATMPVYLNALSGEGVHVVTVNEYLATRDSNEMGELYNFLGLSVGLNINSKS
SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRSQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKSTALYTRADNF
VKRLKEDEDYKIDIQSKTIGLTEAGIEKAEQTFGLDNLYDIENTALTHHLDQALRANYIMLLDIDYVVQDNKVLIVDQFT
GRIMDGRRYSDGLHQAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVIQIPTNRPIIR
DDRPDLLYPTLESKFNAVVEDIKERYHKGQPVLVGTVAVETSELLSDKLNAAKIPHEVLNAKNHFKEAEIIMNAGQKGAV
TIATNMAGRGTDIKLGLGVLELGGLAVIGTERHESRRIDNQLRGRAGRQGDPGVSQFYLSLEDDLMKRFGSERIKTFLER
MNVQEEDAVIQSKMFTRQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYAQRQEVIMEENDLSDVLMGMVKRTIGRV
VDSHTQLEKEEWNLDGIVDFAASTLVHEDTISKKDLENKSAEEIKDYLVARAQEVFEEKSQQLNGQEQLLEFEKVVILRV
VDTKWTDHIDAMDQLRQSVGLRAYGQNNPLVEYQTEGYSMYNNMVGSIEYEVTRLFMKSEIRQNVQREQVAQGQAEHPET
EQDAAAQSNTSAKRQPVRVDKKVGRNDLCPCGSGKKFKNCHGRNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-143 44