Name : thyA (EF1576) Accession : NP_815293.1 Strain : Enterococcus faecalis V583 Genome accession: NC_004668 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 1529048 - 1529995 bp Length : 948 bp Strand : + Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGGAAGAAGCATACTTAGCGCTAGGAAAAAAGATTTTAGAAGAAGGTCATTTTAAAGAAGACCGTACAGGAACTGGGAC GTATAGTTTATTTGGCTATCAAATGCGTTTTGATTTGGCCAAAGGATTTCCCTTACTAACAACCAAACGAGTACCGTTTG GCTTGATTAAAAGTGAGTTATTGTGGTTTTTAAAAGGCGACACGAATATTCGCTATTTGTTAGAGCGAAATAATCATATT TGGGATGAATGGGCGTTCGAACGTTACGTAAAAAGCGCAGATTATCAAGGACCAGACATGACGGATTTTGGGCATCGTGT CTTACAAGATCCAGCGTTTGCAGAACAATACAAAGAAGAACATCAAAAATTCTGTGATGCCATTTTAAATGATGCAGAGT TTGCAGAAAAATATGGTGAATTAGGGAATATTTATGGTGCACAATGGCGTCACTGGGAAACCAAAGATGGTAGCTTTATC GATCAATTAGCTAATGTGATTGAAATGATTAAAACCAATCCTGATTCTCGCCGTTTAATTGTTTCCGCTTGGAATCCAGA AGATGTGCCTTCAATGGCGTTGCCGCCTTGTCACACTATGTTTCAATTTTATGTAAATGAAGGAAAATTAAGCTGTCAAC TTTATCAGCGCAGTGCCGATGTTTTTTTAGGTGTTCCTTTTAACATTGCAAGCTATGCTTTATTGACACATCTGATTGCG CATGAAACAGGTTTAGAAGTGGGGGAGTTTGTACACACGCTAGGAGATGCCCACTTATATCAAAATCATGTGGAACAAAT GCAAGAACAATTATCACGAGAAGTTCGTTCTTTCCCAACGCTCGTTTTGAATCCAGACAAGGCTTCTGTTTTTGATTTTG ATATGGAAGATATTAAAGTAGAAGGCTATGACCCACATCCAACGATTAAAGCGCCGATTGCCGTATAA Protein sequence : MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKRVPFGLIKSELLWFLKGDTNIRYLLERNNHI WDEWAFERYVKSADYQGPDMTDFGHRVLQDPAFAEQYKEEHQKFCDAILNDAEFAEKYGELGNIYGAQWRHWETKDGSFI DQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIA HETGLEVGEFVHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKVEGYDPHPTIKAPIAV |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
thyA | YP_189147.1 | thymidylate synthase | Not tested | ¥ÕSP¥â | Protein | 7e-103 | 68 |