Gene Information

Name : EF0149 (EF0149)
Accession : NP_813951.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Virulence
Product : aggregation substance
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 146450 - 150367 bp
Length : 3918 bp
Strand : +
Note : identified by match to PFAM protein family HMM PF02706

DNA sequence :
ATGAATCAACAGACTGAAGTAAAAAAACGTTTTAAAATGTATAAGGCAAAGAAACACTGGATTGTAGCCCCTATTCTTTT
TTTAGGTGTATTAGGAGCTGTAGGATTAGCTACAGATAATGTACAAGCCGCGGAATTAGATACGCAACCAGGAACAACGA
CGGTGCAACCCGATAATCCCAACCCGCAGTCACGAAATGAAACACTTAAAACGGCAGTATCTGAAGAAGCAGCATTACAA
AAAGACACTACTTCTCAACCAACCACAGCAGAAGAAGTAGTGCCGAAAGGAATTGCTGCTGAACAAAGTTCAGCTACCTC
AAATGATACCACAAACGTCCAACAACCAACAGCAGAAGCAGAAAAATCAGCACAAGAACAACCAGTAGTCAGCCCTGAAA
CAACCATTGAACCTCTAGGGCAGCCAACAGAAGTTGCACCAGCAGAAAATGACGCTAATAAATCAACGTCAATTCCTAAA
GAATTTGAAACACCAGACGTTGACAAAGCAGTTGATGAAGCGAAAAAAGATCCAAACATTACCGTCGTGGAAAAACCAAC
TGAAGACTTAGGAAATGTTTCTTCTAAAGATTTAGCTGCAAAAGAAAAAGAAGTAGACCAACTACAAAAAGAACAAGCCC
AAAAGATTGCCCAACAAGCAGCTGAATTAAAAGCCAAAAATGAAAAAATTGCCAAAGAAAATGCAGAAATTGCGGCAAAA
AATAAAGCGGAAAAAGAGCGCTACGAAAAAGAAGTGGCGGAATACAACAAACACAAAAATGACAAAGGCTATGTGAATGA
AGCAATCAGCAAAGACTTAGTTTTTGATTCAAGCATTGTGACTAAGGATACTAAAATAGACAAGATTACAGGTGGCAAGT
TTATTAAAGCTTCCGATTTTAACAAAGTAAACCAAGGACAATCCAAAGATATTTTTACAAAATTAAGTAAGGATATGAAT
GGAAAAGCAACAGGCAACTTCCAAAGCTCAAAAGTGGCTGCTGTTGAATTTGGCCCTAAAGGAGGATACGCGGTTCTTTT
AGAAAAAAACAAACCGGTCAATGTCACGTATACAGGATTAAATGCTAGTTATTTAGACCGAAAAATCACAAAAGCAGAGT
TCATTTATGAACTTCAATCTGCACCAAGTCAAAGCGGCACCTTAAATGCAGTATTTTCGAATGATCCTATTATTACAGCA
TTTGTTGGTACTAAAAATGCCAATGGGAAGGACGTAAAAGTTCGCTTAACCATTAAATTATATGATGCTAATGGCAAAGA
AGTTTTACCAGATAAAGACCATGCCTTTGCCTATGCGTTATCGTCATTAAACTCTAGTCTAGGAACAAATTATAGTGTAG
AACATGCGGAATTTGTTTCAGACTTTGGCTCAAAAAATGAGTTCAAGTATATTAATGGTTCCTACGTAAAGAAACAAGCG
GATGGGAAATTCTACTCAACCGAAGACCTTGATTATGGGACAGGTCCTTCAGGACTAAAAAATAGTGATTGGGACGCTGT
AGGTCATAAAAATGCGTACTATGGTTCTGGTGTAGGTCTAGCTAGAGAGGGTGGACGTATTTCTTTCTCTTTTGGTATGA
CAACCAAAGGAAAAGTCAACCTATCTGGTGCGCAATGGTTTGCCTTTAGTACCAATTTAAATGCGAAATCAATTAGACCA
TACCAAAAGAAAGGGAATCCAAAAGAACCAGAAAAAGCAACAATTGAATTCAATCGATACAAAGCCAATGTCGTTCCTGT
TCTTGTGCCGAATAAAGAAGTCACTGATGGTCAGAAAAATATCAATGATTTAAATGTGAAACGAGGCGATTCTTTACAAT
ACATTGTGACAGGGGATACGACAGAACTTGCCAAAGTAGATCCGAAAACAGTGACAAAACAAGGGATTCGGGATACCTTT
GATGCAGAAAAAGTGACGATTGATTTATCCAAAGTGAAGGTTTATCAAGCAGATGCAAGTCTAAACGAGAAAGACTTAAA
AGCTGTTGCTGCAGCGATTAATTCAGGAAAAGCTATAGACGTGACTGCTTCTTATGTTCTTAATTTAGATCAAAACACCG
TCACAGCAATGATGAAAACCAACGCAGACGGTTCCGTTGTTTTAGCAATGGGGTATAAATATTTACTTGTCTTGCCGTTT
GTAGTGAAAAATGTAGAAGGCGATTTTGAAAATACAGCTGTTCAGCTGACAAATGATGGCGAAACGGTAACAAATACAGT
GATTAACCATGTGCCGGTTAGTAATCCTTCCAAAGATGTAAAAGCAGATAAAAACGGTACAGTTGGCAGTGTTTCTCTAC
ATGATAAAGATATTCCGTTACAAACAAAAATTTATTATGAAGTGAAATCTTCCGAACGTCCAGCTAACTATGGCGGAATT
ACCGAAGAATGGGGCATGAATGATGTCTTGGACACGACCCATGATCGTTTCACAGGTAAATGGCACGCTATTACAAACTA
TGACCTTAAAGTAGGGGACAAAACGTTAAAAGCAGGAACAGATATTTCTGCCTACATTCTTTTAGAAAACAAAGACAATA
AAGACTTGACGTTTACAATGAATCAAGCATTATTAGCAGCGTTAAATGAAGGAAGCAATAAAGTAGGCAAACAAGCTTGG
TCTGTATATCTGGAAGTCGAACGGATCAAAACAGGTGACGTAGAAAATACGCAAACAGAAAACTACAACAAAGAACTTGT
TCGTTCTAATACGGTGGTGACGCATACACCTGATGATCCAAAACCAACCAAAGCCGTTCACAACAAGAAAGGGGAAGATA
TTAACCATGGAAAAGTTGCTCGTGGTGATGTTCTTTCTTATGAAATGACGTGGGACTTAAAAGGGTACGATAAAGACTTT
GCTTTTGACACAGTCGATCTTGCGACAGGAGTTTCTTTCTTCGATGATTACGACGAAACGAAAGTGACACCAATCAAAGA
CTTACTTCGTGTCAAAGATTCTAAAGGGGCAGACATTACGAACCAGTTCACGATCTCTTGGGACGATGCCAAAGGCACGG
TGACAATCTCTGCCAAAGACCCACAAGCCTTTATTCTAGCGTATGGTGGGCAAGAATTGCGTGTAACGCTCCCTACAAAA
GTCAAAGCCAATGTTTCTGGTGATGTTTATAATTCAGCGGAACAAAATACATTTGGTCAACGAATTAAAACAAATACCGT
TGTCAACCATATTCCAAAAGTGAACCCTAAAAAAGACGTGGTTATTAAAGTTGGTGACAAACAAAGTCAAAATGGCGCCA
CAATCAAATTAGGGGAGAAATTCTTCTATGAATTTACAAGTAGTGACATTCCTGCAGAATACGCTGGTGTTGTGGAAGAA
TGGTCGATTAGCGATAAACTAGACGTAAAACATGACAAATTTAGTGGCCAATGGTCTGTGTTTGCCAATTCTAATTTTGT
TTTAGCAGACGGAACCAAAGTGAATAAAGGGGACGACATTTCGAAACTATTCACGATGACCTTTGAACAAGGGGTAGTTA
AAATCACGGCCAGTCAAGCGTTTTTGGATGCGATGAATCTAAAAGAAAACAAACACGTTGCGCACTCATGGAAAGCGTTC
ATTGGTGTAGAACGAATTGCGGCAGGAGACGTTTACAACACAATCGAAGAATCTTTCAACAATGAGAAGATTAAAACTAA
TACGGTAGTGACACATACGCCAGAAAAACCACAAACACCACCAGAAAAAACAGTGATTGTACCACCAACACCAAAAACAC
CACAAGCACCAGTAGAGCCATTAGTGGTAGAAAAAGCAAGTGTGGCACCCGAACTACCTCATACAGGTGAAAAAGAAAAC
ACCCTATTATCTGTACTAGGTGCCGGAATGCTAGTTGGTCTGGCTTGGTTTGGTTTGAAAAAACGTGAAGTGAAATAA

Protein sequence :
MNQQTEVKKRFKMYKAKKHWIVAPILFLGVLGAVGLATDNVQAAELDTQPGTTTVQPDNPNPQSRNETLKTAVSEEAALQ
KDTTSQPTTAEEVVPKGIAAEQSSATSNDTTNVQQPTAEAEKSAQEQPVVSPETTIEPLGQPTEVAPAENDANKSTSIPK
EFETPDVDKAVDEAKKDPNITVVEKPTEDLGNVSSKDLAAKEKEVDQLQKEQAQKIAQQAAELKAKNEKIAKENAEIAAK
NKAEKERYEKEVAEYNKHKNDKGYVNEAISKDLVFDSSIVTKDTKIDKITGGKFIKASDFNKVNQGQSKDIFTKLSKDMN
GKATGNFQSSKVAAVEFGPKGGYAVLLEKNKPVNVTYTGLNASYLDRKITKAEFIYELQSAPSQSGTLNAVFSNDPIITA
FVGTKNANGKDVKVRLTIKLYDANGKEVLPDKDHAFAYALSSLNSSLGTNYSVEHAEFVSDFGSKNEFKYINGSYVKKQA
DGKFYSTEDLDYGTGPSGLKNSDWDAVGHKNAYYGSGVGLAREGGRISFSFGMTTKGKVNLSGAQWFAFSTNLNAKSIRP
YQKKGNPKEPEKATIEFNRYKANVVPVLVPNKEVTDGQKNINDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQGIRDTF
DAEKVTIDLSKVKVYQADASLNEKDLKAVAAAINSGKAIDVTASYVLNLDQNTVTAMMKTNADGSVVLAMGYKYLLVLPF
VVKNVEGDFENTAVQLTNDGETVTNTVINHVPVSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERPANYGGI
TEEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNKVGKQAW
SVYLEVERIKTGDVENTQTENYNKELVRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLKGYDKDF
AFDTVDLATGVSFFDDYDETKVTPIKDLLRVKDSKGADITNQFTISWDDAKGTVTISAKDPQAFILAYGGQELRVTLPTK
VKANVSGDVYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEYAGVVEE
WSISDKLDVKHDKFSGQWSVFANSNFVLADGTKVNKGDDISKLFTMTFEQGVVKITASQAFLDAMNLKENKHVAHSWKAF
IGVERIAAGDVYNTIEESFNNEKIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVAPELPHTGEKEN
TLLSVLGAGMLVGLAWFGLKKREVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0485 NP_814266.1 aggregation substance Virulence Not named Protein 0.0 90
ef0005 AAM75211.1 EF0005 Not tested Not named Protein 0.0 90

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EF0149 NP_813951.1 aggregation substance VFG2171 Protein 0.0 100
EF0149 NP_813951.1 aggregation substance VFG2164 Protein 0.0 92
EF0149 NP_813951.1 aggregation substance VFG2172 Protein 0.0 90
EF0149 NP_813951.1 aggregation substance VFG2173 Protein 0.0 80