Gene Information

Name : lpdA (EF1356)
Accession : NP_815077.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 1330757 - 1332163 bp
Length : 1407 bp
Strand : +
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGGTAGTAGGAGATTTCGCCATTGAACTAGATACAGTCGTAATCGGAGCTGGTCCTGGAGGATACGTTGCCGCAATTCG
TGCCGCAGAAATGGGTCAAAAAGTTGCGATTATCGAACGTGAATACATCGGAGGCGTTTGTTTAAACGTTGGATGTATTC
CTTCAAAAGCTTTAATTGCTGCTGGACATCATTACCAAGAAGCACAAGATTCTTCAACTTTTGGTGTAACAGCTAAAGGA
GTCGAATTAGACTTTGCAAAAACACAAGACTGGAAAGATAACACAGTTGTAAAATCATTAACAGGCGGCGTTGGCATGTT
ATTGAAAAAACACAAAGTAGAAATTATTGAAGGCGAAGCATTCTTCGTTGACGAAAATACATTGCGTGTTATTCACCCAG
ACTCAGCACAAACTTACTCATTCAATAATGCTATTGTAGCAACAGGTTCTCGTCCAATTGAAATCCCAGGATTCAAATTT
GGCGGACGCGTGTTAGATTCTACAGGCGGTTTAAACTTAAAAGAAGTTCCTAAAAAATTCGTTATTATCGGTGGCGGTGT
CATCGGTGCTGAATTAGGTGGCGCTTATGCTAACTTAGGTTCAGAAGTAACAATTTTAGAAGGTAGCCCATCAATTTTAC
CAACTTATGAAAAAGATATGGTTAAAGTTGTCACAGACCACTTCAAGAAGAAAAACGTAACAATCGTGACTTCTGCAATG
GCTAAAGAAGCTGTTGACAATGGCGATAGCGTCACTGTTAAATATGAAGTTAACGGAAAAGAAGAAAGTGTTGAAGCAGA
TTACGTAATGGTCACTGTTGGACGTCGTCCAAACACAGACGACTTAGGCTTAGAACAAGCGGGCGTTGAAATTGGCGAAC
GTGGTTTAATCCCAGTTGACAACCAAGGACGTACTAACGTGAAAAACATCTTCGCAATCGGCGACATCGTACCAGGTGCT
GCGTTAGCGCATAAAGCAAGCTACGAAGCAAAAATTGCTGCTGAAGCAATTTCTGGTAAGAAAGTTGCAGTTGATTACAA
AGCAATGCCAGCTGTTGCCTTTACTGATCCAGAATTGGCAAGCGTTGGTATGACTGTTGCAGAAGCAAAAGAAGCGGGAA
TCGAAGCAAAAGGCTACAAATTCCCATTTGCTGGTAACGGCCGTGCAATCTCTTTAGATAAAACTGAAGGATTCATGCGT
TTAGTTACAACTGTAGAAGACAATGTCATCATCGGTGCACAAATTGCCGGTGTCGGTGCAAGTGACATGATTTCTGAATT
AGCTTTAGCTATTGAATCTGGCATGAATGCAGAAGACATTGCTTTAACAATCCACCCACACCCATCATTGGGCGAAATTA
CTATGGATACAGCTGAATTGGCTTTAGGTTTACCAATTCATATTTAA

Protein sequence :
MVVGDFAIELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIGGVCLNVGCIPSKALIAAGHHYQEAQDSSTFGVTAKG
VELDFAKTQDWKDNTVVKSLTGGVGMLLKKHKVEIIEGEAFFVDENTLRVIHPDSAQTYSFNNAIVATGSRPIEIPGFKF
GGRVLDSTGGLNLKEVPKKFVIIGGGVIGAELGGAYANLGSEVTILEGSPSILPTYEKDMVKVVTDHFKKKNVTIVTSAM
AKEAVDNGDSVTVKYEVNGKEESVEADYVMVTVGRRPNTDDLGLEQAGVEIGERGLIPVDNQGRTNVKNIFAIGDIVPGA
ALAHKASYEAKIAAEAISGKKVAVDYKAMPAVAFTDPELASVGMTVAEAKEAGIEAKGYKFPFAGNGRAISLDKTEGFMR
LVTTVEDNVIIGAQIAGVGASDMISELALAIESGMNAEDIALTIHPHPSLGEITMDTAELALGLPIHI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 4e-88 45