Gene Information

Name : pyk (EF1046)
Accession : NP_814779.1
Strain : Enterococcus faecalis V583
Genome accession: NC_004668
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1010610 - 1012367 bp
Length : 1758 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAAAAAACGAAAATCGTATGTACGATTGGACCAGCTAGTGAATCCGTTGATATGCTAGTAAACTTAATTAATGCAGG
TATGAATGTTTGCCGTTTGAACTTTTCACATGGTGACTACGAAGAGCATGGTGCTCGTATTAAAAACATTCGTGAAGCTG
TAAAAATTACAGGGAAACGCGTAGCGATCTTACTAGATACAAAAGGTCCTGAAATCCGCACAAATGACATGGAAAATGGC
GCAATCACAATGAAAATTGGTGACTCAGTACGTATTTCTATGACAGAAGTTTTAGGAACAAATGAAAAATTCTCAATCAC
TTATCCAGAATTAATCAATGATGTAAACGTAGGTTCACACATTCTTTTAGATGATGGTTTAATCGATTTAGAAGTAACTG
ATATCGACCGTGATGCAAACGAAATCGTAACAGTTGTTAAAAACGAAGGCGTCTTGAAAAACAAAAAAGGCGTTAACGTA
CCAGGCGTTTCTGTAAACTTACCAGGGATCACTGAAAAAGATGCTAACGATATCCGTTTCGGAATTGGTCAAGGAATTGA
CTTTATCGCAGCTAGCTTCGTTCGTCGTGCTTCTGACGTTTTAGAAATCACTAAAATTTTAGAAGAAGAAAACGCAACAC
ACATCCAAATCATTCCTAAAATCGAAAACCAAGAAGGTATCGATAATATCGATGAAATCTTAAAAGTTTCTGATGGTTTA
ATGGTTGCTCGTGGTGACATGGGTGTTGAAATTCCAACAGAAGATGTTCCAGTTGTCCAAAAAGCTTTAATTAAAAAATG
TAATGCTTTAGGTAAACCAGTTATCACTGCAACACAAATGTTAGATTCAATGCAACGTAACCCACGTCCAACACGTGCGG
AAGCAAATGACGTAGCAAACGCAATCTACGATGGAACAGATGCAGTAATGTTATCAGGCGAAACTGCAGCAGGGGATTAC
CCATTAGAAGCTGTTCAAACAATGGCTCGTATTGCAGTTCGTACAGAAGAAACATTAGTTAACCAAGATTCATTCGCATT
GAAATTATATAGCAAAACAGATATGACTGAAGCAATCGGACAATCTGTTGGCCATACAGCACGTAACTTGGGTATCCAAA
CAATCGTTGCGGCAACAGAATCAGGCCATACAGCACGTATGATCTCTAAATACCGTCCAAAAGCACATATCGTTGCAATT
ACGTTCTCAGAACAAAAAGCACGTAGCTTGTCATTATCATGGGGTGTTTACGCAACAGTTGCTGACAAACCATCAAGCAC
AGATGAAATGTTTAATTTAGCTTCAAAAGTATCACAAGAAGAAGGTTATGCTTCAGAAGGTGATTTAATCATTATCACTG
CTGGTGTTCCAGTTGGCGAAAAAGGGACAACAAACTTAATGAAAATTCAAATGATCGGTTCTAAATTAGTTCAAGGTCAA
GGTGTCGGCGAAGAAGCAATTATTGCAAAAGCCGTTGTGGCAGCAACTGCTGAAGAAGCAGTTGCTAAAGCGACTGAAGG
AGCTATTTTAGTTACAAAAACAACAGATAAAGAATACATGCCAGCAATTGAAAAAGCATCAGCATTAGTTGTTGAAGAAG
GTGGTTTAACTTCTCATGCAGCTGTTGTAGCGATTGCGCAAAATATTCCAGTTATCGTAGGTGCTGCAGATGCAACATCA
TTAATTAATAATGACGAAGTGATTACTGTTGATCCTCGTCGTGGTATTGTTTACCGCGGAGCAACAACAGCTATCTAA

Protein sequence :
MKKTKIVCTIGPASESVDMLVNLINAGMNVCRLNFSHGDYEEHGARIKNIREAVKITGKRVAILLDTKGPEIRTNDMENG
AITMKIGDSVRISMTEVLGTNEKFSITYPELINDVNVGSHILLDDGLIDLEVTDIDRDANEIVTVVKNEGVLKNKKGVNV
PGVSVNLPGITEKDANDIRFGIGQGIDFIAASFVRRASDVLEITKILEEENATHIQIIPKIENQEGIDNIDEILKVSDGL
MVARGDMGVEIPTEDVPVVQKALIKKCNALGKPVITATQMLDSMQRNPRPTRAEANDVANAIYDGTDAVMLSGETAAGDY
PLEAVQTMARIAVRTEETLVNQDSFALKLYSKTDMTEAIGQSVGHTARNLGIQTIVAATESGHTARMISKYRPKAHIVAI
TFSEQKARSLSLSWGVYATVADKPSSTDEMFNLASKVSQEEGYASEGDLIIITAGVPVGEKGTTNLMKIQMIGSKLVQGQ
GVGEEAIIAKAVVAATAEEAVAKATEGAILVTKTTDKEYMPAIEKASALVVEEGGLTSHAAVVAIAQNIPVIVGAADATS
LINNDEVITVDPRRGIVYRGATTAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-104 52
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-104 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-104 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-104 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk NP_814779.1 pyruvate kinase VFG0479 Protein 5e-105 52