Gene Information

Name : BT_0745 (BT_0745)
Accession : NP_809658.1
Strain : Bacteroides thetaiotaomicron VPI-5482
Genome accession: NC_004663
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 923309 - 924061 bp
Length : 753 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAAATTTCTGGGAATAATACCTGCCCGCTACGCATCCACCCGTTTCCCTGCGAAACCATTGGCTATGCTGGGGGGGAA
GACGGTGATACAGCGTGTATACGAACAAGTAGCGGGCATCTTGGATGATGCTTATGTGGCTACCGATGACGAACGTATTG
AAGCTGCCGTAAAAGCATTCGGAGGAAAAGTTGTCATGACTTCCATTGATCATAAAAGTGGTACCGACCGCTGCTATGAG
GCGTGCACAAAGATCGGGGGCGACTTTGATGTGGTAGTCAATATACAGGGGGACGAACCTTTCATCCAGCCTTCCCAGCT
GAATGCTGTAAAGGCTTGTTTCGAAGACCCTACCACGCAGATTGCTACGTTGGTGAAGCCTTTCACAGCCGATGAACCGT
TTGCCGTACTGGAGAATGTCAACTCCCCGAAAGTGGTGCTCAACAAGAATTGGAACGCACTTTATTTCAGCCGTTCCATC
ATACCTTTTCAGCGCAATGCCGATAAGGAAGACTGGCTGAAGGGACATACCTATTACAAACATATCGGTCTGTACGCTTA
TCGCACGGAAGTATTGAAGGAGATCACCGCTCTACCGCAATCCTCTCTGGAGTTGGCAGAATCACTCGAACAGTTGCGCT
GGCTGGAGAATGGATATAAAATAAAGGTAGGCATCAGTGACGTGGAAACGATCGGTATCGACACACCGCAGGATCTGAAA
CATGCAGAAGAATTTTTGAAGAACAGAAGCTGA

Protein sequence : 
MKFLGIIPARYASTRFPAKPLAMLGGKTVIQRVYEQVAGILDDAYVATDDERIEAAVKAFGGKVVMTSIDHKSGTDRCYE
ACTKIGGDFDVVVNIQGDEPFIQPSQLNAVKACFEDPTTQIATLVKPFTADEPFAVLENVNSPKVVLNKNWNALYFSRSI
IPFQRNADKEDWLKGHTYYKHIGLYAYRTEVLKEITALPQSSLELAESLEQLRWLENGYKIKVGISDVETIGIDTPQDLK
HAEEFLKNRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-32 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-33 46
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 7e-33 46