Gene Information

Name : BT_0650 (BT_0650)
Accession : NP_809563.1
Strain : Bacteroides thetaiotaomicron VPI-5482
Genome accession: NC_004663
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 800221 - 801918 bp
Length : 1698 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGGAACAAAAAATAAAATTCCCCCGTTCTCAGAAAGTGTATCTGCCGGGTAAACTCTATCCGAACATCCGTGTAGCCAT
GCGGAAAGTTGAACAAGTGCCCAGTGTCAGCTTCGAAGGAGAAGAAAAGATAGCTACTCCGAATCCGGAAGTATATGTAT
ATGACACCAGCGGTCCGTTCAGTGACCCGTCAATGAGCATTGATCTTAAGAAAGGACTTCCCCGCTTACGTGAAGAATGG
ATTGTGGGACGCGGTGACGTAGAGCAACTCCCCGAAATCACTTCGGAATACGGACAAATGAGACGTGATGACAAAAGTCT
GGATCATCTCCGCTTTGAACACATTGCCCTTCCCTATCGTGCCAAAAAGGGAGAAGCCATCACTCAGATGGCATACGCCA
AACGAGGAATCATCACTCCGGAAATGGAATATGTGGCGATCCGCGAAAATATGAACTGTGAGGAACTGGGAATCGAGACT
CACATTACTCCCGAATTTGTCCGTAAAGAAATAGCAGAAGGACATGCAGTGCTGCCTGCCAACATCAATCATCCGGAAGC
CGAACCGATGATTATCGGCCGTAACTTCCTAGTGAAAATCAATACGAATATCGGAAACTCTGCCACCACTTCCAGCATTG
ACGAGGAAGTGGAAAAAGCTTTATGGAGCTGCAAATGGGGAGGTGATACGCTGATGGACCTTTCAACAGGAGAAAATATT
CATGAGACACGTGAATGGATCATCCGCAACTGCCCTGTACCGGTAGGCACTGTGCCTATCTATCAGGCACTTGAGAAAGT
GAATGGCGTAGTGGAAGACCTTAACTGGGAAATCTATCGGGACACACTGATCGAACAATGCGAACAGGGAGTAGATTATT
TTACGATTCATGCAGGTATCCGCCGTCATAATGTTCATCTTGCCGATAAACGTCTGTGCGGCATTGTCAGCCGTGGAGGA
AGCATCATGAGTAAATGGTGTCTGGTGCACGATCAGGAAAGTTTCCTGTATGAACACTTTGACGATATCTGTGATATTCT
GGCTCAATACGACGTTGCCGTATCATTGGGAGACGGACTGCGTCCGGGCTCTATCCATGATGCCAACGACGAAGCACAGT
TTGCAGAACTGGACACGATGGGAGAACTGGTACTTCGTGCATGGGAAAAGAACGTGCAGGCATTTATCGAAGGTCCGGGA
CACGTACCGATGCATAAAATCAAGGAGAACATGGAACGTCAGATCGAGAAATGCCATGATGCGCCATTTTATACACTCGG
CCCTTTAGTGACGGATATCGCTCCTGGCTACGATCACATTACCTCTGCCATCGGAGCTGCTCAAATCGGCTGGTTAGGTA
CAGCTATGCTTTGTTATGTCACTCCGAAAGAGCATCTTGCCCTGCCGGATAAAGAAGACGTACGTGTAGGGGTTATCACT
TATAAGATTGCCGCTCATGCTGCCGACCTTGCCAAAGGGCATCCGGGAGCACAGGTACGCGACAATGCCTTGAGCAAAGC
CCGTTACGAGTTCCGCTGGAAAGATCAGTTCGACTTGTCTCTCGATCCGGAACGGGCACAGGGATATTTCCGCGCGGGAC
ATCACATTGACGGAGAATACTGCACGATGTGCGGACCAAATTTCTGCGCCATGAGATTATCCCGTGATCTGAAGAAAAAT
GCCAAGAGTGATAAATAA

Protein sequence :
MEQKIKFPRSQKVYLPGKLYPNIRVAMRKVEQVPSVSFEGEEKIATPNPEVYVYDTSGPFSDPSMSIDLKKGLPRLREEW
IVGRGDVEQLPEITSEYGQMRRDDKSLDHLRFEHIALPYRAKKGEAITQMAYAKRGIITPEMEYVAIRENMNCEELGIET
HITPEFVRKEIAEGHAVLPANINHPEAEPMIIGRNFLVKINTNIGNSATTSSIDEEVEKALWSCKWGGDTLMDLSTGENI
HETREWIIRNCPVPVGTVPIYQALEKVNGVVEDLNWEIYRDTLIEQCEQGVDYFTIHAGIRRHNVHLADKRLCGIVSRGG
SIMSKWCLVHDQESFLYEHFDDICDILAQYDVAVSLGDGLRPGSIHDANDEAQFAELDTMGELVLRAWEKNVQAFIEGPG
HVPMHKIKENMERQIEKCHDAPFYTLGPLVTDIAPGYDHITSAIGAAQIGWLGTAMLCYVTPKEHLALPDKEDVRVGVIT
YKIAAHAADLAKGHPGAQVRDNALSKARYEFRWKDQFDLSLDPERAQGYFRAGHHIDGEYCTMCGPNFCAMRLSRDLKKN
AKSDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 6e-180 64
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 6e-180 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 6e-179 62