Gene Information

Name : BT_4312 (BT_4312)
Accession : NP_813223.1
Strain : Bacteroides thetaiotaomicron VPI-5482
Genome accession: NC_004663
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 5682813 - 5684087 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTACCATTAAACAAATTACAGAAAATACAGAAGCGGTACTCCGCGGACTGGAAAAAAAGCATTTCAAGAATGCAAA
AGAGACGATTGACGAAGTCATCGCCCTCAACGACAAGAGACGTACTACGCAAAACCTATTAGATAAGAACCTGGCAGAGG
TTAATTCACTTTCCCGCACGATCGGTCAGCTGATGAAAGAAGGAAAGAAAGAAGAAGCCGAAGCTGCACGTGCACGTGTT
GCCGAACTGAAAGAAAGCAACAAAGCGCTGGACGCTACCATGACACAGGCTGCTACAGACATGCAGAATGTACTTTATAC
GATCCCCAACATTCCTTATGACAGCGTACCCGAAGGCGTAGGTGCCGAAGACAATGTCGTAGAAAAGATGGGAGGCATGG
AAACAGAACTTCCCAAAGATGCACTGCCTCACTGGGAACTGGCTAAAAAATACGATTTAATCGATTTCGACCTAGGTGTA
AAGATTACAGGTGCAGGCTTCCCCGTATACAAAGGAAAAGGTGCCCAACTGCAACGTGCCCTGATCAACTTCTTCCTGGA
CGAAGCACGCAAATCCGGATATACTGAAATCATGCCGCCGACAGTAGTCAATGCCGCTTCAGGTTATGGTACAGGCCAGC
TTCCCGACAAAGAAGGACAGATGTATCATTGCGAAGTAGATGATCTCTATCTGATCCCGACAGCCGAAGTACCTGTCACT
AACATCTACCGTGATGTTATCCTGGAAGAAAAACAGTTGCCGATTATGAACTGTGCATACACACAATGTTTCCGTCGCGA
AGCCGGTTCTTACGGTAAAGACGTACGCGGGCTGAACCGTCTGCACGAATTCTCCAAAGTAGAATTAGTGCGTATCGACA
AGCCGGAACATTCTAAAGAATCCCACCAGCAAATGCTTGACCACGTAGAAGGCCTGTTGCAGAAACTGGAACTTCCATAC
CGTATACTCCGCCTTTGTGGTGGTGATATGAGCTTTACTGCTGCGCTTTGTTTCGACTTCGAAGTATACTCCGAAGCACA
GAAACGCTGGCTGGAAGTAAGTTCCGTATCTAACTTCGACACTTACCAGGCCAACCGGCTGAAATGCCGCTACCGTAGTG
CAGAAAAGAAAACAGAACTCTGCCATACGTTAAATGGATCAGCACTGGCACTACCACGTATCGTCGCCGCTTTATTGGAA
AACAATCAAACCCCCGAAGGAATTAGAATTCCTAAAGCATTGGTTCCATACTGCGGTTTCGACATGATAGACTAA

Protein sequence :
MLTIKQITENTEAVLRGLEKKHFKNAKETIDEVIALNDKRRTTQNLLDKNLAEVNSLSRTIGQLMKEGKKEEAEAARARV
AELKESNKALDATMTQAATDMQNVLYTIPNIPYDSVPEGVGAEDNVVEKMGGMETELPKDALPHWELAKKYDLIDFDLGV
KITGAGFPVYKGKGAQLQRALINFFLDEARKSGYTEIMPPTVVNAASGYGTGQLPDKEGQMYHCEVDDLYLIPTAEVPVT
NIYRDVILEEKQLPIMNCAYTQCFRREAGSYGKDVRGLNRLHEFSKVELVRIDKPEHSKESHQQMLDHVEGLLQKLELPY
RILRLCGGDMSFTAALCFDFEVYSEAQKRWLEVSSVSNFDTYQANRLKCRYRSAEKKTELCHTLNGSALALPRIVAALLE
NNQTPEGIRIPKALVPYCGFDMID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-64 44