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Name : leuS (BT_3126) Accession : NP_812038.1 Strain : Bacteroides thetaiotaomicron VPI-5482 Genome accession: NC_004663 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 3983916 - 3986750 bp Length : 2835 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGAGTACAATTTCAGGGAGATTGAAAAGAAGTGGCAGCAAAGGTGGGTGGAAGAGAAAACCTACCAGGTTACGGAAGA CGAATCGAAGCAGAAATTCTATGTATTGAATATGTTCCCTTACCCGTCAGGGGCCGGACTGCATGTAGGGCATCCGCTGG GATACATCGCTTCGGATATTTACGCCCGTTACAAACGACTGCGTGGCTTCAATGTACTCAATCCGATGGGATATGACGCA TATGGTTTGCCAGCGGAACAATACGCTATTCAGACCGGACAGCATCCCGCAATCACTACTAAAGCTAATATCGACCGCTA TCGCGAGCAACTCGACAAAATAGGCTTCTCTTTCGACTGGAGCCGCGAAATCCGTACGTGCGAACCCGAATATTATCACT GGACCCAATGGGCTTTCCAAAAGATGTTCAACAGCTACTACTGCAACGACGAACAGCAGGCACGCCCTATCCAGGAACTG ATCGATGCATTCGCAATCTACGGAAACGAAGGACTCAACGCTGCCTGCAGCGAAGAACTCAGCTTTACCGCCAAAGAATG GAAAGCCAAAAGCGAAAAGGAACAGCAGGAAATCCTGATGAACTACCGCATCGCCTACCTCGGCGAAACGATGGTGAACT GGTGCCAGGCACTGGGAACCGTATTGGCAAATGACGAAGTCATAGACGGCGTCAGCGAACGCGGCGGCTTCCCCGTAGTC CAGAAGAAGATGCGCCAGTGGTGTCTGCGTGTATCCGCTTATGCTCAGCGTCTGCTCGACGGACTGGATACCATCGACTG GACCGAATCACTGAAAGAAACTCAAAAGAACTGGATCGGACGCTCCGAAGGTGCCGAAGTACAGTTCAAGGTAAAAGACA GCGATCTCGAATTTACCATCTTTACTACCCGTGCAGATACCATGTTCGGTGTGACCTTCATGGTTCTGGCTCCGGAAAGT GATCTGGTAGCCCAGCTGACCACTCCCGCCCAGAAAGCAGAAGTAGACGCCTACCTTGACCGCACCAAGAAACGTACGGA ACGCGAACGCATCGCCGACCGCAGCGTGACCGGTGTATTCAGCGGTTCGTATGCTATCAATCCGTTTACAGGTGAAGCAG TGCCCATCTGGATCAGCGATTACGTATTGGCAGGATACGGAACAGGAGCCATCATGGCCGTACCCGCCCACGATAGCCGC GACTATGCTTTCGCCAAGCATTTCGGACTCGAAATCCGCCCGTTGGTAGAAGGTTGTGACGTAAGCGAAGAAAGCTTCGA TGCCAAGGAAGGTATCGTCTGCAACTCTCCGCGTCCGGATGTAACTCCGTACTGTGATCTGTCTCTGAACGGACTGACCA TCAAGGAAGCCATTGAAAAGACCAAGCAATATGTGAAAGAACATAATCTGGGACGTGTGAAAGTGAACTACCGTCTTCGC GACGCCATTTTCTCACGCCAGCGCTACTGGGGGGAACCGTTCCCTGTGTACTACAAAGACGGAATGCCGTACATGATCGA CGAAGACTGTCTGCCGCTGGAACTTCCGGAAGTAGACAAGTTCCTCCCCACCGAAACAGGCGAACCTCCATTGGGACACG CCAAGGAATGGGCGTGGGACACGGTAAACAAGTGCACGGTAGAAAACGAAAAGATCGACAACGTTACCATCTTCCCGCTG GAACTGAACACCATGCCGGGATTCGCCGGTTCTTCCGCATACTATCTGCGCTACATGGACCCGCACAACAACAAAGCATT GGTGGACCCGAAAGTGGACGAATACTGGAAAAACGTAGACCTTTATGTAGGAGGAACGGAACACGCTACCGGACACTTGA TCTACTCCCGTTTCTGGAATAAGTTCCTGCACGATGTAGGTGCATCGGTAGTAGAAGAACCGTTCCAGAAGTTAGTAAAC CAAGGCATGATTCAAGGCCGCAGCAACTTTGTATATCGCATCAAAGATACTCACACCTTCGTTTCACTGAACCTGAAAGA CCAATACGAAGTGACTCCACTTCATGTGGATGTAAACATCGTATCCAATGATATCCTCGACCTGGAAGCATTCAAGGCAT GGCGTCCCGAATATGCGGAAGCAGAGTTTATCCTCGAAGACGGAAAATACATCTGCGGATGGGCGGTTGAGAAGATGAGT AAATCAATGTTCAACGTAGTCAATCCGGATATGATTGTGGACAAATACGGTGCAGACACCCTTCGTATGTACGAAATGTT CCTCGGTCCGGTTGAGCAGTCCAAGCCTTGGGATACGAACGGTATTGACGGTGTACACCGCTTTATCCGTAAGTTCTGGT CATTGTTTTACAGCCGTACCGACGAATATCTGGTGAAAGACGAGCCTGCAACGAAGGAAGAGTTGAAGAGCCTGCACAAA CTGATCAAGAAAGTAACGGGAGATATCGAACAGTTCTCTTACAATACGTCTGTCAGCGCATTCATGATCTGTGTCAACGA ACTTTCCAACTTGAAATGCAACAAGAAAGAGATACTGGAACAGCTCGTTATCACCCTCGCTCCTTTCGCTCCGCACGTTT GCGAAGAACTGTGGGATACACTGGGACACGAAACTTCCGTATGTGACGCCGCATGGCCCGCATACAACGAAGAATATCTG AAAGAAGATACGATCAACTATACCATCTCCTTCAACGGAAAAGCACGCTTCAACATGGAGTTTGACGCTGATGCCGCTTC GGATGCCATCCAGGCTGCCGTATTAGCCGACGAACGTTCGCAGAAGTGGATCGAAGGCAAAACACCGAAGAAGATCATCG TGGTGCCGAAGAAGATTGTAAATGTGGTAGTTTAA Protein sequence : MEYNFREIEKKWQQRWVEEKTYQVTEDESKQKFYVLNMFPYPSGAGLHVGHPLGYIASDIYARYKRLRGFNVLNPMGYDA YGLPAEQYAIQTGQHPAITTKANIDRYREQLDKIGFSFDWSREIRTCEPEYYHWTQWAFQKMFNSYYCNDEQQARPIQEL IDAFAIYGNEGLNAACSEELSFTAKEWKAKSEKEQQEILMNYRIAYLGETMVNWCQALGTVLANDEVIDGVSERGGFPVV QKKMRQWCLRVSAYAQRLLDGLDTIDWTESLKETQKNWIGRSEGAEVQFKVKDSDLEFTIFTTRADTMFGVTFMVLAPES DLVAQLTTPAQKAEVDAYLDRTKKRTERERIADRSVTGVFSGSYAINPFTGEAVPIWISDYVLAGYGTGAIMAVPAHDSR DYAFAKHFGLEIRPLVEGCDVSEESFDAKEGIVCNSPRPDVTPYCDLSLNGLTIKEAIEKTKQYVKEHNLGRVKVNYRLR DAIFSRQRYWGEPFPVYYKDGMPYMIDEDCLPLELPEVDKFLPTETGEPPLGHAKEWAWDTVNKCTVENEKIDNVTIFPL ELNTMPGFAGSSAYYLRYMDPHNNKALVDPKVDEYWKNVDLYVGGTEHATGHLIYSRFWNKFLHDVGASVVEEPFQKLVN QGMIQGRSNFVYRIKDTHTFVSLNLKDQYEVTPLHVDVNIVSNDILDLEAFKAWRPEYAEAEFILEDGKYICGWAVEKMS KSMFNVVNPDMIVDKYGADTLRMYEMFLGPVEQSKPWDTNGIDGVHRFIRKFWSLFYSRTDEYLVKDEPATKEELKSLHK LIKKVTGDIEQFSYNTSVSAFMICVNELSNLKCNKKEILEQLVITLAPFAPHVCEELWDTLGHETSVCDAAWPAYNEEYL KEDTINYTISFNGKARFNMEFDADAASDAIQAAVLADERSQKWIEGKTPKKIIVVPKKIVNVVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-123 | 42 |
