Gene Information

Name : BT_2841 (BT_2841)
Accession : NP_811753.1
Strain : Bacteroides thetaiotaomicron VPI-5482
Genome accession: NC_004663
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3543132 - 3544589 bp
Length : 1458 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGTTACTGAAACAGACAAAAATCGTCGCATCCATTTCGGACAGACGTTGCGATGTGGACTTTATAAAACAGCTGTTTGA
AGCTGGGATGAATGTGGTACGTATGAATACGGCTCACGCTAGCCGTGAAGGTTTTGAAGCGTTGATTGCCAATGTACGTT
CCGTATCCAACCGGATTGCAATCCTCATGGATACCAAAGGACCGGAAGTACGTACAACTGCCAATGCGGAACCGATTCCA
TATCAGATAGGTGATAAAGTAAAGATTGTCGGCAATCCTGATCAGGAGACGACTCGTGAATGTATCGCTGTTTCGTATCC
TAACTTTGTGAACGATTTGAATATCGGAGGTCTGGTTCTGATTGACGATGGTGATCTTGAACTGGAAGTAATCGATAAGA
CAGCCGATTATCTGCTTTGCGAAGTGAAAAACGATGCAACGTTGGGAAGCCGCAAGAGCGTGAACGTCCCGGGTGTTCGT
ATCAATCTTCCTTCATTGACAGAGAAAGACCGTAACAATATACTTTACGCGATTGAAAAGGATATCGATTTCATCGCTCA
CTCTTTCGTGCGCAACCGTCAGGACGTACTTGATATCCGTGAAATTCTGGATGCTCACAATAGTGATATCCGGATTATTG
CCAAGATTGAGAATCAGGAAGGGGTGGACAACATCGACGAGATTCTTGAAGTGGCGGACGGCGTGATGGTAGCCCGTGGT
GACCTGGGTATCGAAGTGCCGCAGGAACGTATTCCGGGTATCCAGCGTGTGCTGATCCGCAAATGTATCCTGGCAAAGAA
ACCGGTGATCGTTGCGACTCAGATGCTTCATACCATGATCAACAATCCTCGTCCGACCCGCGCGGAAGTGACCGATATCG
CGAATGCAATCTACTATCGTACGGATGCTCTGATGTTGAGCGGTGAGACTGCTTATGGCAAATATCCGGTAGATGCAGTC
AAGACAATGACCAAGATCGCGGCCCAGGCTGAAAAAGATAAACTGGAAGAGAATGATATCCGTATCCCGTTGAACGAAAA
CAGTAACGATGTAACGGCCTTCCTTGCTAAACAGGCAGTGAAAGCTACATCGAAACTGAAGATACGTGCCATCATCACAG
ACAGCTATAGCGGACGGACCGCCCGTAATCTGGCAGCTTTCCGTGGTAAGTTCCCGGTATTGGCTATCTGCTATAAAGAA
AAGACCATGCGTCATCTGGCACTTTCTTATGGAGTGGAAGCAATCTATATGCCGGAGCTGGCCAACGGACAGGAATATTA
TTTTGCCGCTTTGCGCCGCCTGTTGAAGGAAGGACGTTTGCAGCCGACTGATATGGTAGGATATCTGAGTAGCGGTAAGG
CAGGTACACAAACTTCATTCCTCGAAATCAATGTCGTGGAAGATGCGTTGAAACATGCGGGAGAAACTGTATTGCCTAAC
AACAATCGTTATCTCTAA

Protein sequence :
MLLKQTKIVASISDRRCDVDFIKQLFEAGMNVVRMNTAHASREGFEALIANVRSVSNRIAILMDTKGPEVRTTANAEPIP
YQIGDKVKIVGNPDQETTRECIAVSYPNFVNDLNIGGLVLIDDGDLELEVIDKTADYLLCEVKNDATLGSRKSVNVPGVR
INLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIRIIAKIENQEGVDNIDEILEVADGVMVARG
DLGIEVPQERIPGIQRVLIRKCILAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVDAV
KTMTKIAAQAEKDKLEENDIRIPLNENSNDVTAFLAKQAVKATSKLKIRAIITDSYSGRTARNLAAFRGKFPVLAICYKE
KTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPTDMVGYLSSGKAGTQTSFLEINVVEDALKHAGETVLPN
NNRYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-76 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-76 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-77 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-75 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BT_2841 NP_811753.1 pyruvate kinase VFG0479 Protein 8e-77 41