Name : thyA (BT_2047) Accession : NP_810960.1 Strain : Bacteroides thetaiotaomicron VPI-5482 Genome accession: NC_004663 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 2568918 - 2569712 bp Length : 795 bp Strand : + Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGAAACAATATTTAGATTTACTCAATCGCGTATTAACTGAAGGAACTGAGAAAAGTGACCGTACAGGAACCGGAACGAT CAGTGTGTTCGGACATCAGATGCGTTTCAACCTCGACGAGGGTTTCCCGTGTCTGACCACCAAAAAACTGCATCTGAAAT CAATCATCTACGAGTTACTCTGGTTTCTGCAAGGTGATACGAACGCGAAATATCTGCAAGAACACGGTGTACGCATCTGG AACGAATGGGCGGACGAGAACGGTGATTTAGGGCATATCTATGGCTATCAGTGGCGTTCGTGGCCCGACTACGACGGCGG ATTCATCGACCAGATCAGCGAAGCGGTAGAGACGATCAAGCACAATCCCGACTCCCGCCGTATCATTGTCAGCGCCTGGA ATGTAGCCGATTTAAAGAATATGAACCTGCCTCCCTGTCATGCCTTCTTCCAGTTTTACGTGGCAGACGGTCGGCTGAGC CTGCAACTTTACCAGCGCAGCGCGGATATATTTCTCGGAGTCCCGTTCAATATCGCATCATATGCACTGCTGCTACAAAT GATGGCGCAGGTGACAGGACTGAAAGCGGGTGAATTTATCCATACACTTGGCGATGCCCATATCTATCTGAACCACTTGG ATCAGGTCAAATTGCAGCTTAGCCGCGAACCACGCGCATTGCCTCAAATGAAAATTAATCCGGATGTGAAGAGTATCTAT GACTTCCAGTTCGAAGACTTCGAACTGGTGAACTACGACCCGCATCCACATATTGCCGGAATAGTAGCGGTATAA Protein sequence : MKQYLDLLNRVLTEGTEKSDRTGTGTISVFGHQMRFNLDEGFPCLTTKKLHLKSIIYELLWFLQGDTNAKYLQEHGVRIW NEWADENGDLGHIYGYQWRSWPDYDGGFIDQISEAVETIKHNPDSRRIIVSAWNVADLKNMNLPPCHAFFQFYVADGRLS LQLYQRSADIFLGVPFNIASYALLLQMMAQVTGLKAGEFIHTLGDAHIYLNHLDQVKLQLSREPRALPQMKINPDVKSIY DFQFEDFELVNYDPHPHIAGIVAV |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 1e-80 | 65 |