Gene Information

Name : umuC (t0881)
Accession : NP_804711.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : 2.7.7.7
Position : 981739 - 983007 bp
Length : 1269 bp
Strand : +
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTCGCGCTCTGCGATGTTAATAGCTTTTACGCCTCCTGCGAAACGGTCTTTCGTCCTGATTTATGTGGCCGACCGGT
GGTGGTGTTATCAAACAATGATGGCTGCGTTATCGCGTGTAGCGCCGAGGCGAAACAACTCGGTATCGCAGCAGGTGAGC
CATACTTCAAACAGAAAGAACGCTTCCGGCGATCCGGTGTTGTTTGCTTCAGCAGTAATTACGAGCTTTACGCTGATATG
TCGAACCAGGTAATGACCACACTAGAGGAGATGGTGCCGCGGGTAGAAATTTACAGCATTGATGAGGCTTTTTGTGATCT
GACGGGGGTACGAAACTGCCGGGATCTGACAGATTTCGGGCACGAGATAAGAGCGACGGTCCTGAAGCGCACGCACCTGA
CTGTCGGTGTAGGCATTGCCCAGACGAAAACCCTTGCCAAGCTGGCTAACCATGCTGCGAAAAAGTGGCAGCGCCAGACC
GACGGGGTGGTTGACCTGTCGAACATCGATCGCCAGCGTCGGCTGCTGGCCCTGATACCCGTAGAGGATGTCTGGGGTGT
CGGCAGACGCATCAGTAAGAAGCTCAATGCCCTGGGCATCAAGACTGCTCTCGATCTCTCTGAACAAAGTACCTGGATCA
TCAGGAAACACTTCAATGTCGTGCTGGAGCGTACCGTGAGAGAGCTTCGCGGAGAGCCATGTCTGGAGCTTGAAGAGTTT
GCGCCGGCAAAGCAGGAAATCGTTTGTAGCCGCTCTTTCGGCGAGCGGGTCACAGACTATGAGGAAATGCGCCAGGCTGT
TTACAGCTACGCTGCGCGCGCGGCAGAAAAACTCCGCGGCGAGCACCAGTACTGCTGTTTCATTTCAACATTCGTCAAAA
CATCACCCTTTGCCCTGAACGAGCCCTACTACGGTAACAGCGCCGCGGTGACGCTTCTCACCCCCACGCAGGATTCACGT
GACATTATCAATGCGGCTGTGAAATGTCTGGATAAAATCTGGCGCGACGGCCATCGCTACCAGAAAGCGGGGGTGATGCT
GGGTGGCTTCTTCAGCCAGGGCGTAGCGCAACTCAACCTTTTCGACGATAACGCGCCGCGCGCCGGTAGTGCGAAGTTGA
TGGAAGTACTGGACCATCTTAACGCAAAAGACGGGAAGGGGACGCTGTACTTCGCCGGGCAGGGGATGTCGCAACAGTGG
GCTATGAAGCGAGAAATGCTTTCGCCTCGGTACACCACAAGATACTCTGATCTACTGCGTGTTAAGTAA

Protein sequence :
MFALCDVNSFYASCETVFRPDLCGRPVVVLSNNDGCVIACSAEAKQLGIAAGEPYFKQKERFRRSGVVCFSSNYELYADM
SNQVMTTLEEMVPRVEIYSIDEAFCDLTGVRNCRDLTDFGHEIRATVLKRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
DGVVDLSNIDRQRRLLALIPVEDVWGVGRRISKKLNALGIKTALDLSEQSTWIIRKHFNVVLERTVRELRGEPCLELEEF
APAKQEIVCSRSFGERVTDYEEMRQAVYSYAARAAEKLRGEHQYCCFISTFVKTSPFALNEPYYGNSAAVTLLTPTQDSR
DIINAAVKCLDKIWRDGHRYQKAGVMLGGFFSQGVAQLNLFDDNAPRAGSAKLMEVLDHLNAKDGKGTLYFAGQGMSQQW
AMKREMLSPRYTTRYSDLLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 7e-121 62
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 7e-121 62
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 6e-89 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 2e-76 49