Gene Information

Name : umuC (t4291)
Accession : NP_807889.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : 2.7.7.7
Position : 4456072 - 4457346 bp
Length : 1275 bp
Strand : -
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTCGCCCTGGCTGACGTCAACAGCTTCTACGCGAGCTGTGAAAAAGTATTTCGTCCCGATTTACGTAATACACCTGT
TGTGGTGCTCAGTAACAACGATGGATGTGTTATCGCGCGTTCAAAAGAAGCGAAGCAACTGGGCATTAAAATGGGGGTTC
CGTGGTTTCAACTGAAAACAACCGAATTTCCTGTACCTGTCGTTGCGTTCTCGAGTAACTACGAACTCTACGCGTCGATG
TCGAACCGTGTTATGGCGCATCTCGAAGAACTGGCACCTCGCGTTGAGCAGTATTCTATCGACGAAATGTTTCTTGATGT
GCGCAATATTGACAGTTGTATCGATTTTGAAGACTTCGGCCGGCAGTTGCGCGAGCATGTACATTCAGGAACCGGACTGA
CCATCGGAGTTGGGATGGGACCGACCAAGACACTGGCAAAAAGCGCACAATGGGCGTCTAAGGAATGGCGGCAGTTTGAG
GGCGTGCTTGCTCTGACTTCAGGCAATCCAAAGCGAACGGAGAAACTATTGTCACTGCAGCCAGTAGACGAAATCTGGGG
GGTTGGTCGCCGGATCTCGAAGAAACTGCACACAATGGGGATAACAACTGCACTGCAGCTGGCGCGCGCGAACCCAACAT
TTATCAGGAAAAATTTCAGTGTTGTTCTCGAGAGAACTGTCCGTGAACTGAACGGGGAAAGCTGTATTTCACTGGAGGAG
GCTCCGCCACCCAAGCAGCAGATTGTCTGCAGCCGATCCTTTGGGGAGCGCGTCACAACATATGAAGCCATGCGCCAGGC
AGTCTGTCAGTATGCTGAGCGTGCAGCTGAAAAGCTGCGCGGCGAGCGGCAATTCTGCAGACATGTTGCTGTATTTGTGA
AGACGTCACCGTTCGCTGTGAACGAACCGTATTACGGGAATGTGGCCAGTGAGAAACTGACGACTCCCACGCAGGATACC
AGGGACATCATAGCCGCAGCGGTGAAAGCACTGGATCGGATCTGGGTGAAAGGGCATAGATATGCAAAAGCGGGTTGCAT
GCTCAATGATTTCACACCAACCGGGATTTCTCAGTTAAATCTTTTTGATGAAGTGCAGCCGCACGAACGAAGTGAGCAGT
TGATGAAAGTTCTCGACAGTATCAACCATTCAGGTATGGGAAAAGTGTGGTTTGCCGGAAGAGGGATAGCCCCTGAGTGG
CAGATGAAAAGAGAGCTACTCTCTCCAGCTTATACCACTCGCTGGGCTGAATTACCTGTTGCACGATTGCGCTGA

Protein sequence :
MFALADVNSFYASCEKVFRPDLRNTPVVVLSNNDGCVIARSKEAKQLGIKMGVPWFQLKTTEFPVPVVAFSSNYELYASM
SNRVMAHLEELAPRVEQYSIDEMFLDVRNIDSCIDFEDFGRQLREHVHSGTGLTIGVGMGPTKTLAKSAQWASKEWRQFE
GVLALTSGNPKRTEKLLSLQPVDEIWGVGRRISKKLHTMGITTALQLARANPTFIRKNFSVVLERTVRELNGESCISLEE
APPPKQQIVCSRSFGERVTTYEAMRQAVCQYAERAAEKLRGERQFCRHVAVFVKTSPFAVNEPYYGNVASEKLTTPTQDT
RDIIAAAVKALDRIWVKGHRYAKAGCMLNDFTPTGISQLNLFDEVQPHERSEQLMKVLDSINHSGMGKVWFAGRGIAPEW
QMKRELLSPAYTTRWAELPVARLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 0.0 100
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 0.0 100
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 1e-81 46
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 2e-65 44